Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Edgar Perez-Mata"'
Autor:
Raul Sanchez-Muñoz, Edgar Perez-Mata, Lorena Almagro, Rosa M. Cusido, Mercedes Bonfill, Javier Palazon, Elisabeth Moyano
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Engineered plant cell lines have the potential to achieve enhanced metabolite production rates, providing a high-yielding source of compounds of interest. Improving the production of taxanes, pharmacologically valuable secondary metabolites of Taxus
Externí odkaz:
https://doaj.org/article/66e86be3ae0d4c358df2d92dea3e4c51
Autor:
Rosa M. Cusidó, Mercedes Bonfill, Raul Sanchez-Muñoz, Elisabeth Moyano, Javier Palazon, Lorena Almagro, Edgar Perez-Mata
Publikováno v:
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
Dipòsit Digital de la UB
Universidad de Barcelona
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Frontiers in Bioengineering and Biotechnology
Dipòsit Digital de la UB
Universidad de Barcelona
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Frontiers in Bioengineering and Biotechnology
Engineered plant cell lines have the potential to achieve enhanced metabolite production rates, providing a high-yielding source of compounds of interest. Improving the production of taxanes, pharmacologically valuable secondary metabolites of Taxus
Autor:
Edgar Perez-Matas, Diego Hidalgo-Martinez, Ainoa Escrich, Miguel Angel Alcalde, Elisabeth Moyano, Mercedes Bonfill, Javier Palazon
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
Paclitaxel (PTX) and its derivatives are diterpene alkaloids widely used as chemotherapeutic agents in the treatment of various types of cancer. Due to the scarcity of PTX in nature, its production in cell cultures and plant organs is a major challen
Externí odkaz:
https://doaj.org/article/17808a83f7f0455089140f2d217ef975
Autor:
Edgar Perez-Matas, Pascual Garcia-Perez, Begoña Miras-Moreno, Luigi Lucini, Mercedes Bonfill, Javier Palazon, Diego Hidalgo-Martinez
Publikováno v:
Plants, Vol 12, Iss 14, p 2696 (2023)
Taxus cell cultures are a reliable biotechnological source of the anticancer drug paclitaxel. However, the interplay between taxane production and other metabolic pathways during elicitation remains poorly understood. In this study, we combined untar
Externí odkaz:
https://doaj.org/article/550dc5229b14462b940aca5edc3e7dac
Autor:
Edgar Perez-Matas, Abdulsamie Hanano, Elisabeth Moyano, Mercedes Bonfill, Rosa M. Cusido, Javier Palazon
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
More knowledge is needed about the molecular/cellular control of paclitaxel (PTX) production in Taxus spp. cell cultures. In this study, the yield of this anticancer agent in Taxus baccata cell suspensions was improved 11-fold after elicitation with
Externí odkaz:
https://doaj.org/article/2907f2452635478ab2d2272ed0ec5f15
Autor:
Edgar Perez-Matas, Pascual Garcia-Perez, Mercedes Bonfill, Luigi Lucini, Diego Hidalgo-Martinez, Javier Palazon
Publikováno v:
Antioxidants, Vol 12, Iss 4, p 887 (2023)
Elicited cell cultures of Taxus spp. are successfully used as sustainable biotechnological production systems of the anticancer drug paclitaxel, but the effect of the induced metabolomic changes on the synthesis of other bioactive compounds by elicit
Externí odkaz:
https://doaj.org/article/f0ac2eb5170a41a19821ae16504179a6
Autor:
Lourdes Pérez, María Teresa García, Aurora Pinazo, Edgar Pérez-Matas, Zakaria Hafidi, Elena Bautista
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2602 (2022)
Cationic surfactants have great potential as drug vehicles and for use in gene therapy (cationic vesicles made from cationic surfactants can encapsulate RNA or DNA for cellular transfer). They can also be used as antimicrobial and antifungal agents t
Externí odkaz:
https://doaj.org/article/473bfdc803264c7b92a773e09f095b82
Autor:
Miguel Angel Alcalde, Edgar Perez-Matas, Ainoa Escrich, Rosa M. Cusido, Javier Palazon, Mercedes Bonfill
Publikováno v:
Molecules, Vol 27, Iss 16, p 5253 (2022)
One of the aims of plant in vitro culture is to produce secondary plant metabolites using plant cells and organ cultures, such as cell suspensions, adventitious, and hairy roots (among others). In cases where the biosynthesis of a compound in the pla
Externí odkaz:
https://doaj.org/article/6e54744b062c441b961beb64c8094ae7