Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Edgar Lederer"'
Publikováno v:
Infection and Immunity. 32:273-276
The antitumor activity of a mixture of synthetic N-acetylmuramyl-L-alanyl-D-isoglutamine (MDP) and trehalose-6,6'-dimycolate (TDM) (MDP+TDM) in emulsified form was studied in guinea pigs, each with a syngeneic dermal tumor and microscopically detecta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c58b6264c8b223c4067e3ac8c974e8ee
https://doi.org/10.1128/iai.32.1.273-276.1981
https://doi.org/10.1128/iai.32.1.273-276.1981
Autor:
Victor R. Villanueva, Edgar Lederer
Publikováno v:
Phytochemistry. 13:2157-2160
By using two different isotopically labelled precursors and ion exchange aminoacid analysis, it is shown that the methyl group of methionine is incorporated into e-N-mono-, di- and trimethylated derivatives of lysine found in the free state in the ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd53fdeef8432fe62d433cb8ebf2a840
https://doi.org/10.1016/0031-9422(74)85019-3
https://doi.org/10.1016/0031-9422(74)85019-3
Publikováno v:
International Journal of Cancer. 22:564-569
Injection of emulsified 6,6'-di-O-2-tetradecyl-3-hydroxyoctadecanoyl-a, a trehalose designated C76, a synthetic analogue of the mycobacterial glycolipid trehalose-6,6'-dimycolate (TDM), into transplants of an established, syngeneic murine fibrosarcom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b601b52022a6e3d49b30f79e182d1a
https://doi.org/10.1002/ijc.2910220510
https://doi.org/10.1002/ijc.2910220510
Autor:
Jean Choay, Edgar Lederer, Manfred L. Karnovsky, James M. Walter, Louis Chedid, James M. Krueger, Pierre Lefrancier
Publikováno v:
The Journal of Experimental Medicine
Sleep-promoting activities of muramyl dipeptide (MDP) (NAc-Mur-L-ala-D-isogln) and the naturally occurring muramyl peptide(s), factor S, have recently been demonstrated. We now have amplified our understanding of structural requirements for somnogeni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21c83a265384ad25a3670eeb8853f627
https://doi.org/10.1084/jem.159.1.68
https://doi.org/10.1084/jem.159.1.68
Publikováno v:
Proceedings of the National Academy of Sciences. 74:2089-2093
N-Acetylmuramyl-L-alanyl-D-isoglutamine and four other synthetic adjuvants that are structural analogs of part of the mycobacterial peptidoglycan monomer are shown to enhance the nonspecific immunity of mice infected by Klebsiella pneumoniae. These c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589f127993a5469ba992811a55f4e379
https://doi.org/10.1073/pnas.74.5.2089
https://doi.org/10.1073/pnas.74.5.2089
Publikováno v:
Infection and Immunity. 26:462-466
Intratumoral injection of ultrasonically prepared emulsions of the synthetic glycolipid methly 6-O-(2-tetradecyl-3-hydroxyoctadecanoyl)-alpha-D-glucopyranoside (designated C39) induced complete regression of transplants of a syngeneic murine fibrosar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96fd339b67ea547a6bda7298b05801b5
https://doi.org/10.1128/iai.26.2.462-466.1979
https://doi.org/10.1128/iai.26.2.462-466.1979
Autor:
Victor R. Villanueva, Edgar Lederer
Publikováno v:
FEBS Letters. 52:308-311
A new ϵ- N -trimethyllysine metabolite has been isolated from the mycelium of Neurospora crassa . The labelled compound produced from incubations in vivo and in vitro from ϵ- N -trimethyl ([ 14 C]H 3 )L-lysine has been identified as 2-keto-ϵ- N -t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8017f8f84cd49132fc0f6ebbad501f8
https://doi.org/10.1016/0014-5793(75)80832-5
https://doi.org/10.1016/0014-5793(75)80832-5
Autor:
Edgar Lederer
Publikováno v:
Journal of Medicinal Chemistry. 23:819-825
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d1e774acb3acfae67827e489915a2f1
https://doi.org/10.1021/jm00182a001
https://doi.org/10.1021/jm00182a001
Publikováno v:
European Journal of Immunology. 10:647-653
Immunomodulators of bacterial origin, such as muramyl-dipeptide (MDP) and trehalose dimycolate, are able to stimulate some important biological functions of macrophages, such as their capacity to secrete a monokine, the thymocyte mitogenic protein (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856a1deb4460c33911c7153b22c351f6
https://doi.org/10.1002/eji.1830100813
https://doi.org/10.1002/eji.1830100813