Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Edgar K. Hudson"'
Autor:
Daniel B. Gazda, Leslie J. Loh, William T. Wallace, Tyler J. Marlar, Sarah L. Wallace, C. K. Mike Kuo, Edgar K. Hudson
Publikováno v:
Acta Astronautica. 141:30-35
Maintaining a safe supply of potable water is of utmost importance when preparing for long-duration spaceflight missions, with the minimization of microbial growth being one major aspect. While biocides, such as ionic silver, historically have been u
Autor:
Linda Shackelford, Sara R. Zwart, Martina Heer, Scott M. Smith, Jean D. Sibonga, J. M. Spatz, Edgar K. Hudson, Robert Pietrzyk
Publikováno v:
Bone. 81:712-720
Bone loss and renal stone risk are longstanding concerns for astronauts. Bone resorption brought on by spaceflight elevates urinary calcium and the risk of renal stone formation. Loss of bone calcium leads to concerns about fracture risk and increase
Autor:
Scott M. Smith, Sara R. Zwart, Martina Heer, Edgar K. Hudson, Jennifer L. L. Morgan, Linda Shackelford
Publikováno v:
Journal of Bone and Mineral Research. 29:1639-1645
Bone loss, a key concern for long-duration space travelers, is typically considered a female issue. The number of women who have flown long-duration space missions is now great enough to allow a quantitative comparison of changes in bone and renal st
Autor:
Martina Heer, Alan R. Hargens, Jennifer L. L. Morgan, Scott M. Smith, Linda Shackelford, Edgar K. Hudson, Brandon R. Macias, Sara R. Zwart
Publikováno v:
Physiological Reports
The purpose of this study was to directly assess sex differences in bone loss, bone biochemistry, and renal stone risk in bed rest. Bed rest simulates some spaceflight effects on human physiology and can be used to address the potential existence of
Autor:
Edgar K. Hudson, Jennifer R. Morgan, Scott A. Smith, Sara R. Zwart, Martina Heer, Linda Shackelford
Publikováno v:
The FASEB Journal. 28
Bone loss on Earth is more prevalent in women than men, leading to the assumption that women may be at greater risk from bone loss during flight. Until recently, the number of women having flown long-duration missions was too small to allow any type
Autor:
Edgar K. Hudson, Brandon R. Macias, Sara R. Zwart, Allen Hargens, Scott A. Smith, Linda Shackelford, Martina Heer, Jennifer R. Morgan
Publikováno v:
The FASEB Journal. 28
Autor:
Colette M. J. Ap Rhys, Edgar K. Hudson, Richard G. Hansford, Vilhelm A. Bohr, Grigory L. Dianov, Deborah L. Croteau
Publikováno v:
Journal of Biological Chemistry. 272:27338-27344
Reactive oxygen species have been shown to generate mutagenic lesions in DNA. One of the most abundant lesions in both nuclear and mitochondrial DNA is 7,8-dihydro-8-oxoguanine (8-oxoG). We report here the partial purification and characterization of
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 271:H422-H427
The mitochondrial carnitine palmitoyltransferase (CPT) system is composed of two proteins, CPT-I and -II, which, together with carnitine acylcarnitine translocase, are involved in the transport of fatty acids into the mitochondrial matrix for beta-ox
Autor:
Peggy A. Whitson, Edgar K. Hudson, Clarence Sams, Mayra Nelman-Gonzalez, Robert A. Pietrzyk, Jeffrey A. Jones
Publikováno v:
The Journal of urology. 182(5)
Exposure to microgravity affects human physiology and results in changes in urinary chemical composition during and after spaceflight, favoring an increased risk of renal stones. We assessed the efficacy of potassium citrate to decrease the stone ris
Publikováno v:
Europe PubMed Central
The oxidatively induced DNA lesion 8-oxo-dG in mitochondrial DNA (mtDNA) is commonly used as a marker for oxidative damage to mitochondria, which in turn is thought to be a fundamental cause of aging. For years, mitochondrial levels of 8-oxo-dG were