Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Edgar J. Wakayama"'
Autor:
Edgar J. Wakayama, Edson X. Albuquerque, Yasco Aracava, G. William Basinger, Edna F. R. Pereira, Louis J. DeTolla, E. Jeffrey Beecham
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 350:313-321
The translational capacity of data generated in preclinical toxicological studies is contingent upon several factors, including the appropriateness of the animal model. The primary objectives of this article are: 1) to analyze the natural history of
Autor:
Patrick J. Sabourin, Edgar J. Wakayama, Seth Gibbs, Kristen M. Patton, Carol L. K. Sabourin, Peter Hong, Claire M. Matthews, Christina L. Kobs
Publikováno v:
International journal of toxicology. 35(5)
Potassium cyanide (KCN) is an inhibitor of cytochrome C oxidase causing rapid death due to hypoxia. A well-characterized model of oral KCN intoxication is needed to test new therapeutics under the Food and Drug Administration Animal Rule. Clinical si
Autor:
T. G. Jenkins, L. J. Coleman, Edgar J. Wakayama, Gary J. Blomquist, Curtiss M. Bailey, Jeffrey M. Eichhorn
Publikováno v:
Journal of Animal Science. 63:781-794
Fatty acid composition and cholesterol content of muscle and adipose tissue from mature cows (N = 101) representing 15 breeds and crosses were determined. An initial group of cows was slaughtered after being fed slightly above the maintenance level f
Autor:
Gary J. Blomquist, Mertxe de Renobales, J. George Pomonis, Edgar J. Wakayama, Ronald C. Reitz, Premjit P. Halarnkar
Publikováno v:
Archives of Insect Biochemistry and Physiology. 3:75-86
The elongation of [9,10-3H]oleoyl-CoA with malonyl-CoA to form 20, 22, and 24 carbon monounsaturated fatty acids was demonstrated in housefly microsomes by radio-GLC. These elongation reactions, which have been postulated to be involved in hydrocarbo
Publikováno v:
Insect Biochemistry. 15:367-374
Gas-liquid chromatography (GLC) on polar, non-polar and capillary columns and chemical ionization-gas chromatography-mass spectrometry (CI-GC-MS) were used to verify the presence of arachidonic acid (20:4) and eicosatrienoic acid (20:3, n-6) at low l
Publikováno v:
Insect Biochemistry. 14:175-179
Vitamin B 12 concentrations were determined by radioassay in the housefly, five species of termites, and 17 other phylogenetically diverse insect species. Vitamin B 12 was not detected in the housefly Musca domestica , which apparently cannot interco
Publikováno v:
Insect Biochemistry. 16:903-909
The in vitro formation of prostaglandins (PG) was examined in the housefly Musca domestica . PG synthetase activity was detected in homogenates of whole insects and in head and thorax, abdomen, ovary and male reproductive tissues. Studies to determin
Publikováno v:
Insect Biochemistry. 16:895-902
Prostaglandins (PGs) of the E and F series were quantified in the housefly by radioimmunoassay (RIA). Whole insects and reproductive tissues from both sexes contained PGE (1+2) and PDG 2α which increased in amount with age. PGF 2α levels were highe
Publikováno v:
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry. 88:869-873
1. 1. Vitamin B 12 levels were determined in centipede, millipede, spider, isopod, leech, earthworm, tubifex worm, snail, clam and shrimp. All contained appreciable amounts of vitamin B 12 , which ranged from 19 to 4013 pg/mg dry wt. 2. 2. The metabo
Publikováno v:
Phytochemistry. 27:997-999
No detectable levels of vitamin B 14 were present in the leaves and stems of the lima bean, Phaseolus limensis . [2- 14 C]Propionate was metabolized to 3-hydroxypropionate, acetate and other organic acids in a time dependent manner. At no time period