Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Edgar Creus-Bachiller"'
1
Akademický článek
Expanding a precision medicine platform for malignant peripheral nerve sheath tumors: New patient‐derived orthotopic xenografts, cell lines and tumor entities
Autor: Edgar Creus‐Bachiller, Juana Fernández‐Rodríguez, Miriam Magallón‐Lorenz, Sara Ortega‐Bertran, Susana Navas‐Rutete, Cleofe Romagosa, Tulio M. Silva, Maria Pané, Anna Estival, Diana Perez Sidelnikova, Mireia Morell, Helena Mazuelas, Meritxell Carrió, Tereza Lausová, David Reuss, Bernat Gel, Alberto Villanueva, Eduard Serra, Conxi Lázaro
Publikováno v: Molecular Oncology, Vol 18, Iss 4, Pp 895-917 (2024)
Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft‐tissue sarcomas with a poor survival rate, presenting either sporadically or in the context of neurofibromatosis type 1 (NF1). The histological diagnosis of MPNSTs can be challen
Externí odkaz: https://doaj.org/article/7781165f8bd2471e855029a3e508c066
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3
Akademický článek
Use of patient derived orthotopic xenograft models for real-time therapy guidance in a pediatric sporadic malignant peripheral nerve sheath tumor
Autor: Juana Fernández-Rodríguez, Andrés Morales La Madrid, Bernat Gel, Alicia Castañeda Heredia, Héctor Salvador, María Martínez-Iniesta, Catia Moutinho, Jordi Morata, Holger Heyn, Ignacio Blanco, Edgar Creus-Bachiller, Gabriel Capella, Lourdes Farré, August Vidal, Francisco Soldado, Lucas Krauel, Mariona Suñol, Eduard Serra, Alberto Villanueva, Conxi Lázaro
Publikováno v: Therapeutic Advances in Medical Oncology, Vol 12 (2020)
Background: The aim of this study was to test the feasibility and utility of developing patient-derived orthotopic xenograft (PDOX) models for patients with malignant peripheral nerve sheath tumors (MPNSTs) to aid therapeutic interventions in real ti
Externí odkaz: https://doaj.org/article/02b45471cb414606bd6321400e909f5f
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7
A high-throughput screening platform identifies novel combination treatments for Malignant Peripheral Nerve Sheath Tumors
Autor: Juana Fernández-Rodríguez, Edgar Creus-Bachiller, Xiaohu Zhang, Maria Martínez-Iniesta, Sara Ortega-Bertran, Rajarshi Guha, Craig J. Thomas, Margaret R. Wallace, Cleofe Romagosa, Lourdes Salazar-Huayna, Karlyne M. Reilly, Jaishri O. Blakely, Jordi Serra-Musach, Miguel Angel Pujana, Eduard Serra, Alberto Villanueva, Marc Ferrer, Conxi Lázaro
Publikováno v: Mol Cancer Ther
Molecular Cancer Therapeutics
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Malignant peripheral nerve sheath tumors (MPNST) are soft-tissue sarcomas that are the leading cause of mortality in patients with Neurofibromatosis type 1 (NF1). Single chemotherapeutic agents have shown response rates ranging from 18% to 44% in cli
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4a0bf5d46410009b07abaca8c6936a3
https://europepmc.org/articles/PMC9256801/
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8
Use of patient derived orthotopic xenograft models for real-time therapy guidance in a pediatric sporadic malignant peripheral nerve sheath tumor
Autor: Ignacio Blanco, Mariona Suñol, Andres Morales La Madrid, Catia Moutinho, Gabriel Capellá, Holger Heyn, Conxi Lázaro, Jordi Morata, Juana Fernández-Rodríguez, María Martínez-Iniesta, Alicia Castañeda Heredia, August Vidal, Edgar Creus-Bachiller, Francisco Soldado, Alberto Villanueva, Hector Salvador, Lourdes Farre, Lucas Krauel, Eduard Serra, Bernat Gel
Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
Therapeutic Advances in Medical Oncology
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Therapeutic Advances in Medical Oncology, Vol 12 (2020)
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
Background: The aim of this study was to test the feasibility and utility of developing patient-derived orthotopic xenograft (PDOX) models for patients with malignant peripheral nerve sheath tumors (MPNSTs) to aid therapeutic interventions in real ti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c911a7b6f51978a624b26b4fd3f4f3
https://doi.org/10.1177/1758835920929579
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9
Generation of two compound heterozygous HGSNAT-mutated lines from healthy induced pluripotent stem cells using CRISPR/Cas9 to model Sanfilippo C syndrome
Autor: Daniel Grinberg, María García-Morant, Edgar Creus-Bachiller, Isaac Canals, Noelia Benetó, Mónica Cozar, Lluïsa Vilageliu
Publikováno v: Stem Cell Research. 41:101616
Sanfilippo C syndrome (Mucopolysaccharidosis IIIC) is a rare lysosomal storage disorder caused by mutations in the HGSNAT gene. It is characterized by a progressive and severe neurodegeneration, for which there is no treatment available. Here, we rep
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a799264443e37b82554b6f028fc36e1
https://doi.org/10.1016/j.scr.2019.101616
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