Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Edgar A. Jaimes"'
Autor:
Shinobu Yamaguchi, Randee Sedaka, Chintan Kapadia, Jifeng Huang, Jung-Shan Hsu, Taylor F. Berryhill, Landon Wilson, Stephen Barnes, Caleb Lovelady, Yasin Oduk, Ryan M. Williams, Edgar A. Jaimes, Daniel A. Heller, Takamitsu Saigusa
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Rapamycin slows cystogenesis in murine models of polycystic kidney disease (PKD) but failed in clinical trials, potentially due to insufficient drug dosing. To improve drug efficiency without increasing dose, kidney-specific drug delivery ma
Externí odkaz:
https://doaj.org/article/280c5588929545ad941f6861d8fa44d3
Autor:
Bruna Visniauskas, Danielle Y. Arita, Carla B. Rosales, Mohammed A. Feroz, Christina Luffman, Michael J. Accavitti, Gabrielle Dawkins, Jennifer Hong, Andrew C. Curnow, Tina K. Thethi, John J. Lefante, Edgar A. Jaimes, Franck Mauvais-Jarvis, Vivian A. Fonseca, Minolfa C. Prieto
Publikováno v:
Biology of Sex Differences, Vol 12, Iss 1, Pp 1-12 (2021)
Abstract Background The soluble prorenin receptor (sPRR), a member of the renin-angiotensin system (RAS), is elevated in plasma of patients with preeclampsia, hypertension, chronic kidney disease (CKD), and type 2 diabetes. Our goal was to examine th
Externí odkaz:
https://doaj.org/article/15b60cad9206474fba6afd8158c096b0
Autor:
Ryan M. Williams, Janki Shah, Elizabeth Mercer, Helen S. Tian, Vanessa Thompson, Justin M. Cheung, Madeline Dorso, Jaclyn M. Kubala, Lorraine J. Gudas, Elisa de Stanchina, Edgar A. Jaimes, Daniel A. Heller
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Cisplatin-induced acute kidney injury (CI-AKI) is a significant co-morbidity of chemotherapeutic regimens. While this condition is associated with substantially lower survival and increased economic burden, there is no pharmacological agent to effect
Externí odkaz:
https://doaj.org/article/e9c80bc4acc04c6f88b6be37ff8b7f51
Autor:
Januka Budhathoki-Uprety, Janki Shah, Joshua A. Korsen, Alysandria E. Wayne, Thomas V. Galassi, Joseph R. Cohen, Jackson D. Harvey, Prakrit V. Jena, Lakshmi V. Ramanathan, Edgar A. Jaimes, Daniel A. Heller
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Microalbuminuria, a clinical marker associated with cancer and hypertension, defined by low albumin levels in the urine, is normally detected by immunoassay. Herein, a nanosensor paint was developed using a polymer to mimic fatty acid binding to albu
Externí odkaz:
https://doaj.org/article/84ad4bc60aee45148a7ef379969a0af8
Autor:
Rhodora C. Calizo, Smiti Bhattacharya, J. G. Coen van Hasselt, Chengguo Wei, Jenny S. Wong, Robert J. Wiener, Xuhua Ge, Nicholas J. Wong, Jia-Jye Lee, Christina M. Cuttitta, Gomathi Jayaraman, Vivienne H. Au, William Janssen, Tong Liu, Hong Li, Fadi Salem, Edgar A. Jaimes, Barbara Murphy, Kirk N. Campbell, Evren U. Azeloglu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Kinase inhibitors used in chemotherapy are known for their adverse effects on kidney physiology. Here, Calizo et al. show that dasatinib is associated with a higher risk of glomerular toxicity compared to other kinase inhibitors, due to deleterious e
Externí odkaz:
https://doaj.org/article/8269d038cbb047b6863d44efd06fc28f
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12, p 6439 (2021)
The organic cation transporter 2 (OCT2) and multidrug and toxin extrusion protein 1 (MATE1) mediate the renal secretion of drugs. Recent studies suggest that ondansetron, a 5-HT3 antagonist drug used to prevent nausea and vomiting, can inhibit OCT2-
Externí odkaz:
https://doaj.org/article/00318440cf3b4bc0a5adedc0c6a4566e
Autor:
Subhashini Bolisetty, Edgar A. Jaimes
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 3, Pp 6306-6344 (2013)
The air that we breathe contains nearly 21% oxygen, most of which is utilized by mitochondria during respiration. While we cannot live without it, it was perceived as a bane to aerobic organisms due to the generation of reactive oxygen and nitrogen m
Externí odkaz:
https://doaj.org/article/0119f7e3408e4202ab0113fc4f070b7a
Autor:
Yan-Ting Shiu, Edgar A. Jaimes
Publikováno v:
Antioxidants, Vol 7, Iss 7, p 84 (2018)
The E26 avian erythroblastosis virus transcription factor-1 (ETS-1) is a member of the ETS family and regulates the expression of a variety of genes including growth factors, chemokines and adhesion molecules. Although ETS-1 was discovered as an onco
Externí odkaz:
https://doaj.org/article/722b4bcd9e2f4237ae697b0250b151fa
Publikováno v:
Kidney International Reports. 8:360-364
El presente libro es producto de los esfuerzos investigativos de colegas latinoamericanos e iberoamericanos que desde sus instituciones han procurado abordar el problema de la migración como resultado de la descomposición de los sistemas de liberta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f72ff2b174e4cdfc6e8a51417c4c00