Zobrazeno 1 - 10
of 203
pro vyhledávání: '"Edgar, Meinl"'
Autor:
Stephan Winklmeier, Heike Rübsamen, Ceren Özdemir, Paul R. Wratil, Gaia Lupoli, Marcel Stern, Celine Schneider, Katharina Eisenhut, Samantha Ho, Hoi Kiu Wong, Damla Taskin, Marvin Petry, Michael Weigand, Peter Eichhorn, Bärbel U. Foesel, Simone Mader, Oliver T. Keppler, Tania Kümpfel, Edgar Meinl
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The mucosal immunity is crucial for restricting SARS-CoV-2 at its entry site. Intramuscularly applied vaccines against SARS-CoV-2 stimulate high levels of neutralizing Abs in serum, but the impact of these intramuscular vaccinations on features of mu
Externí odkaz:
https://doaj.org/article/9d42e7c5f3d24fc18847cc55adb70e1e
Autor:
Valerie E. Teschner, Ann-Katrin Fleck, Carolin Walter, Anna-Sophie Schwarze, Melanie Eschborn, Timo Wirth, Olga V. Steinberg, Andreas Schulte-Mecklenbeck, I-Na Lu, Marisol Herrera-Rivero, Claudia Janoschka, Jan D. Lünemann, Nicholas Schwab, Gerd Meyer zu Hörste, Julian Varghese, Catharina C. Gross, Refik Pul, Christoph Kleinschnitz, Simone Mader, Edgar Meinl, Monika Stoll, Heinz Wiendl, Luisa Klotz
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 16 (2023)
Background: Cladribine is a highly effective immunotherapy that is applied in two short-term courses over 2 years and reduces relapse rate and disease progression in patients with relapsing multiple sclerosis (MS). Despite the short treatment period,
Externí odkaz:
https://doaj.org/article/620f3b4ae03d47ceb2b1381faa850bb4
Autor:
Ramona Gerhards, Lena Kristina Pfeffer, Jessica Lorenz, Laura Starost, Luise Nowack, Franziska S. Thaler, Miriam Schlüter, Heike Rübsamen, Caterina Macrini, Stephan Winklmeier, Simone Mader, Mattias Bronge, Hans Grönlund, Regina Feederle, Hung-En Hsia, Stefan F. Lichtenthaler, Juliane Merl-Pham, Stefanie M. Hauck, Tanja Kuhlmann, Isabel J. Bauer, Eduardo Beltran, Lisa Ann Gerdes, Aleksandra Mezydlo, Amit Bar-Or, Brenda Banwell, Mohsen Khademi, Tomas Olsson, Reinhard Hohlfeld, Hans Lassmann, Tania Kümpfel, Naoto Kawakami, Edgar Meinl
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-17 (2020)
Abstract Autoimmune disorders of the central nervous system (CNS) comprise a broad spectrum of clinical entities. The stratification of patients based on the recognized autoantigen is of great importance for therapy optimization and for concepts of p
Externí odkaz:
https://doaj.org/article/48e9a477e7444c7f8deb69565051b888
Autor:
Stephan Winklmeier, Katharina Eisenhut, Damla Taskin, Heike Rübsamen, Ramona Gerhards, Celine Schneider, Paul R. Wratil, Marcel Stern, Peter Eichhorn, Oliver T. Keppler, Matthias Klein, Simone Mader, Tania Kümpfel, Edgar Meinl
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103659- (2022)
Summary: Although some COVID-19 patients maintain SARS-CoV-2-specific serum immunoglobulin G (IgG) for more than 6 months postinfection, others eventually lose IgG levels. We assessed the persistence of SARS-CoV-2-specific B cells in 17 patients, 5 o
Externí odkaz:
https://doaj.org/article/421780233e7e4232a603f35bf55f7e8d
Autor:
Matthias Mulazzani, Marion Huber, Sabine Borchard, Sigrid Langer, Barbara Angele, Elisabeth Schuh, Edgar Meinl, Martin Dreyling, Tobias Birnbaum, Andreas Straube, Uwe Koedel, Louisa von Baumgarten
Publikováno v:
Journal of Hematology & Oncology, Vol 12, Iss 1, Pp 1-14 (2019)
Abstract Background Early diagnosis of CNS lymphoma (CNSL) is essential for successful therapy of this rapidly progressing brain tumor. However, in patients presenting with focal brain lesions, fast and reliable diagnosis of PCNSL remains a challenge
Externí odkaz:
https://doaj.org/article/e046c16b32fc49108c15c6b8da0ca691
Autor:
Matea Konjevic Sabolek, Kathrin Held, Eduardo Beltrán, Anna G. Niedl, Edgar Meinl, Reinhard Hohlfeld, Hans Lassmann, Klaus Dornmair
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 7, Pp 1151-1164 (2019)
Abstract Objective CD8+ T cells are the most prevailing lymphocyte population in inflammatory lesions of patients with multiple sclerosis (MS) but it is not even known whether they are merely passive bystanders or actively communicate with other cell
Externí odkaz:
https://doaj.org/article/a533e9b65ada4237a45ef0474b841ca2
Autor:
Frederike C. Oertel, Olivier Outteryck, Benjamin Knier, Hanna Zimmermann, Nadja Borisow, Judith Bellmann-Strobl, Astrid Blaschek, Sven Jarius, Markus Reindl, Klemens Ruprecht, Edgar Meinl, Reinhard Hohlfeld, Friedemann Paul, Alexander U. Brandt, Tania Kümpfel, Joachim Havla
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-9 (2019)
Abstract Background Serum antibodies against myelin-oligodendrocyte-glycoprotein (MOG-IgG) are detectable in a proportion of patients with acute or relapsing neuroinflammation. It is unclear, if neuro-axonal damage occurs only in an attack-dependent
Externí odkaz:
https://doaj.org/article/1d77307b005e4edfa8a8475b0aec1366
Autor:
Stefan Preisendörfer, Yoshihiro Ishikawa, Elisabeth Hennen, Stephan Winklmeier, Jonas C. Schupp, Larissa Knüppel, Isis E. Fernandez, Leonhard Binzenhöfer, Andrew Flatley, Brenda M. Juan-Guardela, Clemens Ruppert, Andreas Guenther, Marion Frankenberger, Rudolf A. Hatz, Nikolaus Kneidinger, Jürgen Behr, Regina Feederle, Aloys Schepers, Anne Hilgendorff, Naftali Kaminski, Edgar Meinl, Hans Peter Bächinger, Oliver Eickelberg, Claudia A. Staab-Weijnitz
Publikováno v:
Cells, Vol 11, Iss 8, p 1341 (2022)
Antibodies are central effectors of the adaptive immune response, widespread used therapeutics, but also potentially disease-causing biomolecules. Antibody folding catalysts in the plasma cell are incompletely defined. Idiopathic pulmonary fibrosis (
Externí odkaz:
https://doaj.org/article/eee505bfb71a48c3bf92f6658efc3879
Autor:
Mahya Eslami, Edgar Meinl, Hermann Eibel, Laure Willen, Olivier Donzé, Ottmar Distl, Holm Schneider, Daniel E. Speiser, Dimitrios Tsiantoulas, Özkan Yalkinoglu, Eileen Samy, Pascal Schneider
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
B cell activation factor of the TNF family (BAFF/BLyS), an essential B cell survival factor of which circulating levels are elevated in several autoimmune disorders, is targeted in the clinic for the treatment of systemic lupus erythematosus (SLE). T
Externí odkaz:
https://doaj.org/article/76027ff55cba448a9c4dc593f4326ad2
Autor:
Luise Appeltshauser, Helena Junghof, Julia Messinger, Janis Linke, Axel Haarmann, Ilya Ayzenberg, Panoraia Baka, Johannes Dorst, Anna L Fisse, Thomas Grüter, Valerie Hauschildt, Alexander Jörk, Frank Leypoldt, Mathias Mäurer, Edgar Meinl, Sebastian Michels, Jeremias Motte, Kalliopi Pitarokoili, Mark Stettner, Carmen Villmann, Marc Weihrauch, Gabriel S Welte, Inga Zerr, Katrin G Heinze, Claudia Sommer, Kathrin Doppler
Publikováno v:
Brain 146(5), 1932-1949 (2023). doi:10.1093/brain/awac418
Autoimmune neuropathy associated with antibodies against pan-neurofascin is a new subtype of nodo-paranodopathy. It is relevant because it is associated with high morbidity and mortality. Affected patients often require intensive care unit treatment