Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Eder Gambeta"'
Autor:
Charlie H. T. Kwok, Erika K. Harding, Nicole E. Burma, Tamara Markovic, Nicolas Massaly, Nynke J. van den Hoogen, Sierra Stokes-Heck, Eder Gambeta, Kristina Komarek, Hye Jean Yoon, Kathleen E. Navis, Brendan B. McAllister, Julia Canet-Pons, Churmy Fan, Rebecca Dalgarno, Evgueni Gorobets, James W. Papatzimas, Zizhen Zhang, Yuta Kohro, Connor L. Anderson, Roger J. Thompson, Darren J. Derksen, Jose A. Morón, Gerald W. Zamponi, Tuan Trang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Opioid withdrawal is a liability of chronic opioid use and misuse, impacting people who use prescription or illicit opioids. Hyperactive autonomic output underlies many of the aversive withdrawal symptoms that make it difficult to discontinu
Externí odkaz:
https://doaj.org/article/d65c6d8ddef244efbd66f10b378d8cc2
Autor:
Heloísa Alonso-Matielo, Zizhen Zhang, Eder Gambeta, Junting Huang, Lina Chen, Gabriel Oliveira de Melo, Camila Squarzoni Dale, Gerald W. Zamponi
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-5 (2023)
Abstract The insula and anterior cingulate cortex (ACC) are brain regions that undergo structural and functional reorganization in neuropathic pain states. Here, we aimed to study inhibitory parvalbumin positive (PV+) posterior insula (pIC) to poster
Externí odkaz:
https://doaj.org/article/5a4288109786492782bfb6db69a25f8d
Autor:
Emilio R. Mustafá, Eder Gambeta, Robin N. Stringer, Ivana A. Souza, Gerald W. Zamponi, Norbert Weiss
Publikováno v:
Molecular Brain, Vol 15, Iss 1, Pp 1-14 (2022)
Abstract Trigeminal neuralgia (TN) is a rare form of chronic neuropathic pain characterized by spontaneous or elicited paroxysms of electric shock-like or stabbing pain in a region of the face. While most cases occur in a sporadic manner and are acco
Externí odkaz:
https://doaj.org/article/9ec48b506f2a4dafb732afc422aa57dd
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-6 (2021)
Abstract A novel missense mutation in the CACNA1A gene that encodes the pore forming α1 subunit of the CaV2.1 voltage-gated calcium channel was identified in a patient with trigeminal neuralgia. This mutation leads to a substitution of proline 2455
Externí odkaz:
https://doaj.org/article/3cc3992953204bed8f442b984f867f90
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 475:711-718
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10de90a5196bec16052bd55dd771832b
https://doi.org/10.1007/s00424-023-02808-w
https://doi.org/10.1007/s00424-023-02808-w
Publikováno v:
Pain. 163:2315-2325
Trigeminal neuralgia (TN) is a rare but debilitating disorder characterized by excruciating facial pain, with a higher incidence in women. Recent studies demonstrated that TN patients present mutations in the gene encoding the Ca V 3.2 T-type calcium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f592e25e097555ad89d5bdd71e428832
https://doi.org/10.1097/j.pain.0000000000002651
https://doi.org/10.1097/j.pain.0000000000002651
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 474:447-454
This study describes the interaction between CaV3.2 calcium channels and the receptor for activated C kinase 1 (Rack-1), a scaffold protein which has recently been implicated in neuropathic pain. The coexpression of CaV3.2 and Rack-1 in tsA-201 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a7a7c002c4a15e901aaad277efa8419
https://doi.org/10.1007/s00424-021-02631-1
https://doi.org/10.1007/s00424-021-02631-1
Autor:
Eder Gambeta
Publikováno v:
Frontiers in Clinical Drug Research-CNS and Neurological Disorders ISBN: 9789815040678
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6f1812ada2a499b2f84481bbf8079ff
https://doi.org/10.2174/97898150406781221001
https://doi.org/10.2174/97898150406781221001
Autor:
Agustin Garcia-Caballero, Vinicius M. Gadotti, Md Yousof Ali, Chris Bladen, Eder Gambeta, Jeffrey F. Van Humbeck, Justin L. MacCallum, Gerald W. Zamponi
Publikováno v:
ACS chemical neuroscience. 13(4)
Cav3.2 calcium channels are important mediators of nociceptive signaling in the primary afferent pain pathway, and their expression is increased in various rodent models of chronic pain. Previous work from our laboratory has shown that this is in par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e3e7294c7add14fa5b1c526a1064c61
https://pubmed.ncbi.nlm.nih.gov/35113527
https://pubmed.ncbi.nlm.nih.gov/35113527