Lipidomic signatures align with inflammatory patterns and outcomes in critical illness

Autor: Wu, Junru, Cyr, Anthony, Gruen, Danielle S., Lovelace, Tyler C., Benos, Panayiotis V., Das, Jishnu, Kar, Upendra K., Chen, Tianmeng, Guyette, Francis X., Yazer, Mark H., Daley, Brian J., Miller, Richard S., Harbrecht, Brian G., Claridge, Jeffrey A., Phelan, Herb A., Zuckerbraun, Brian S., Neal, Matthew D., Johansson, Pär I., Stensballe, Jakob, Namas, Rami A., Vodovotz, Yoram, Sperry, Jason L., Billiar, Timothy R., Zenati, Mazen S., Brown, Joshua B., Triulzi, Darrell J., Young, Barbara J.Early, Adams, Peter W., Alarcon, Louis H., Callaway, Clifton W., Forsythe, Raquel M., Yealy, Donald M., Peitzman, Andrew B., Buck, Meghan L., Ryman, Ashley M., Gimbel, Elizabeth A., Gilchrist, Erin G., Buhay, Meghan, Chang, Chung Chou H., Talisa, Victor B., Xu, Tianyuan, Kalloway, Kyle, Yates, Andrew, Rawn, Susan, Jenkins, Judith M., Trachtenberg, Laura S., Eden, Randi K., Fraifogl, Joanne, Bates, Craig, Howard, Christina

Publikováno v: Research Square
article-version (status) pre
article-version (number) 1
Wu, J, Cyr, A, Gruen, D S, Lovelace, T C, Benos, P V, Das, J, Kar, U K, Chen, T, Guyette, F X, Yazer, M H, Daley, B J, Miller, R S, Harbrecht, B G, Claridge, J A, Phelan, H A, Zuckerbraun, B S, Neal, M D, Johansson, P I, Stensballe, J, Namas, R A, Vodovotz, Y, Sperry, J L, Billiar, T R, Zenati, M S, Brown, J B, Triulzi, D J, Young, B J E, Adams, P W, Alarcon, L H, Callaway, C W, Forsythe, R M, Yealy, D M, Peitzman, A B, Buck, M L, Ryman, A M, Gimbel, E A, Gilchrist, E G, Buhay, M, Chang, C C H, Talisa, V B, Xu, T, Kalloway, K, Yates, A, Rawn, S, Jenkins, J M, Trachtenberg, L S, Eden, R K, Fraifogl, J, Bates, C, Howard, C & PAMPer study group 2022, ' Lipidomic signatures align with inflammatory patterns and outcomes in critical illness ', Nature Communications, vol. 13, no. 1, 6789 . https://doi.org/10.1038/s41467-022-34420-4

Alterations in lipid metabolism have the potential to be markers as well as drivers of the pathobiology of acute critical illness. Here, we took advantage of the temporal precision offered by trauma as a common cause of critical illness to identify t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f94d1e570f40f42f13f1826fce39745
https://doi.org/10.1038/s41467-022-34420-4