An angiotensin II receptor antagonist reduces inflammatory parameters in two models of colitis

Autor: Edelmarie Rivera, Olga I. Santiago, León Ferder, Caroline B. Appleyard

Publikováno v: Regulatory Peptides. 146:250-259

Little is known about the effects of the pro-inflammatory hormone Angiotensin II (Ang II) in inflammatory bowel disease. The aim of this study was to evaluate the effect of valsartan (Diovan), an Ang II receptor antagonist, in two models of colitis.C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e882095e68b1606d430ff93e32d144c
https://doi.org/10.1016/j.regpep.2007.10.004

Molecular profiling of a rat model of colitis: Validation of known inflammatory genes and identification of novel disease-associated targets

Autor: Elizabeth Rivera, Caroline B. Appleyard, Idhaliz Flores, Edelmarie Rivera

Publikováno v: Inflammatory Bowel Diseases. 12:950-966

Background: Inflammatory bowel disease (IBD) is a disease of unknown etiology characterized by acute and chronic relapsing inflammation. The most suitable animal model for studying this disease is still under debate. Microarray transcript profiling h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91423055d8c98abd152085d97affd745
https://doi.org/10.1097/01.mib.0000231575.11678.8c

Role of neurokinin‐1 receptor during the transition of inflammation to dysplasia in a colitis‐associated colon cancer model

Autor: Beatriz Pagan, Domenico Coppola, Angel A. Isidro, Jie Wu, Caroline B. Appleyard, Edelmarie Rivera

Publikováno v: The FASEB Journal. 22

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::50d9b1ba938cb442a66a68e4eb4aaf62
https://doi.org/10.1096/fasebj.22.1_supplement.898.28

S1956 Expression of S100 Proteins May Help Screen for the Transition of Chronic Inflammation to Dysplasia

Autor: Edelmarie Rivera, Jose Serrano, Beatriz Pagan, Richard J. Noel, Virgilio Salvo, Caroline B. Appleyard, Angel A. Isidro

Publikováno v: Gastroenterology. 138:S-289

Patients with Inflammatory Bowel Disease (IBD) are at increased risk of developing colorectal cancer. The use of biomarkers to aid in the early detection and diagnosis of colorectal cancer is of interest due to their potential to improve treatment pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::091558a2b8ce7e483da2c268d7856f61
https://doi.org/10.1016/s0016-5085(10)61327-3

Adoptive Transfer of Dendritic Cells Expressing Fas Ligand Modulates Intestinal Inflammation in a Model of Inflammatory Bowel Disease.

Autor: de Jesus ER; Ponce Health Sciences University-Medical School and Ponce Research Institute, Ponce, PR 00732, USA; Department of Biology, University of Puerto Rico - Ponce Campus, Ponce, PR 00732, USA., Isidro RA; Ponce Health Sciences University-Medical School and Ponce Research Institute, Ponce, PR 00732, USA., Cruz ML; Ponce Health Sciences University-Medical School and Ponce Research Institute, Ponce, PR 00732, USA., Marty H; Ponce Health Sciences University-Medical School and Ponce Research Institute, Ponce, PR 00732, USA., Appleyard CB; Ponce Health Sciences University-Medical School and Ponce Research Institute, Ponce, PR 00732, USA.

Publikováno v: Journal of clinical & cellular immunology [J Clin Cell Immunol] 2016 Apr; Vol. 7 (2). Date of Electronic Publication: 2016 Apr 29.