Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Edeildo Ferreira da Silva‐Júnior"'
Publikováno v:
Acta Materia Medica, Vol 3, Iss 3, Pp 345-348 (2024)
Recent groundbreaking advances in the structural biology of the glucose transporter 9 (GLUT9) and urate transporter 1 (URAT1) have provided critical insights into the molecular mechanisms underlying urate recognition and transport. Using cryo-electro
Externí odkaz:
https://doaj.org/article/0a508a2ca28a4a77a5daae21b9e39266
Autor:
Chuanfeng Liu, Lide Hu, Guanyu Dong, Ying Zhang, Edeildo Ferreira da Silva-Júnior, Xinyong Liu, Luis Menéndez-Arias, Peng Zhan
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 12, Pp 4715-4732 (2023)
Influenza is an acute respiratory infection caused by influenza viruses (IFV), According to the World Health Organization (WHO), seasonal IFV epidemics result in approximately 3–5 million cases of severe illness, leading to about half a million dea
Externí odkaz:
https://doaj.org/article/ba338528a0f242a1834806a96f944096
Autor:
Kadja Luana Chagas Monteiro, Marcone Gomes dos Santos Alcântara, Thiago Mendonça de Aquino, Edeildo Ferreira da Silva-Júnior
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 5, Pp 990-991 (2021)
Externí odkaz:
https://doaj.org/article/134b9b615b0047f6b153d2beb1100b1e
Autor:
Gabriel Felipe Silva Passos, Matheus Gabriel Moura Gomes, Thiago Mendonça de Aquino, João Xavier de Araújo-Júnior, Stephannie Janaina Maia de Souza, João Pedro Monteiro Cavalcante, Elane Conceição dos Santos, Ênio José Bassi, Edeildo Ferreira da Silva-Júnior
Publikováno v:
Pharmaceuticals, Vol 13, Iss 7, p 141 (2020)
Chikungunya virus (CHIKV) causes an infectious disease characterized by inflammation and pain of the musculoskeletal tissues accompanied by swelling in the joints and cartilage damage. Currently, there are no licensed vaccines or chemotherapeutic age
Externí odkaz:
https://doaj.org/article/df35a0460d7c4867beab13875d80f991
Autor:
Wanessa Azevedo de Brito, Monique Gomes Dantas, Fernando Henrique Andrade Nogueira, Edeildo Ferreira da Silva-Júnior, João Xavier de Araújo-Júnior, Thiago Mendonça de Aquino, Êurica Adélia Nogueira Ribeiro, Lilian Grace da Silva Solon, Cícero Flávio Soares Aragão, Ana Paula Barreto Gomes
Publikováno v:
Molecules, Vol 22, Iss 9, p 1394 (2017)
Guanylhydrazones are molecules with great pharmacological potential in various therapeutic areas, including antitumoral activity. Factorial design is an excellent tool in the optimization of a chromatographic method, because it is possible quickly ch
Externí odkaz:
https://doaj.org/article/7b5a269f1c37444eae4766ee7c672f1c
Autor:
Xiaoyu Shi, Tong Zhao, Edeildo Ferreira da Silva-Júnior, Jian Zhang, Shujing Xu, Shenghua Gao, Xinyong Liu, Peng Zhan
Publikováno v:
Expert Opinion on Therapeutic Patents. 32:1175-1184
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::373441cf9c098fd70e5122d883b8599e
https://doi.org/10.1080/13543776.2022.2165911
https://doi.org/10.1080/13543776.2022.2165911
Publikováno v:
Combinatorial Chemistry & High Throughput Screening. 25:2317-2340
Inflammation is a natural process that occurs in the organism in response to harmful external agents. Despite being considered beneficial, exaggerated cases can cause severe problems for the body. The main inflammatory manifestations are pain, increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::229a55a5d91dcd4e965154249cd59b8f
https://doi.org/10.2174/1386207324666210715165943
https://doi.org/10.2174/1386207324666210715165943
Publikováno v:
Letters in Drug Design & Discovery. 19:951-955
Abstract: Drug design and discovery is a process that requires high financial costs and is timeconsuming. For many years, this process focused on empirical pharmacology. However, over the years, the target-based approach allowed a significant discove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58861b665860def60173dce95cf7b6b7
https://doi.org/10.2174/1570180819666220405225817
https://doi.org/10.2174/1570180819666220405225817
Autor:
Igor José dos Santos Nascimento, Kadja Luana Chagas Monteiro, Osmar Nascimento Silva, Francisco Jaime Bezerra Mendonça Júnior, Pedro Gregório Vieira Aquino, Edeildo Ferreira da Silva-Júnior, Thiago Mendonça de Aquino
Publikováno v:
Current Topics in Medicinal Chemistry. 22:1983-2028
ABSTRACT: The discovery of antibiotics was a revolutionary feat that provided countless health bene-fits. The identification of penicillin by Alexander Fleming initiated the era of antibiotics, represent-ed by constant discoveries that enabled effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27f1ae77297d55d8ccdd2a325babcc7e
https://doi.org/10.2174/1568026622666220321124452
https://doi.org/10.2174/1568026622666220321124452
Autor:
Edeildo Ferreira da Silva-Júnior, Leandro Rocha Silva, Jéssica Alves Nunes, Peng Zhan, Krzysztof Z. Łączkowski, Sílvia Helena Cardoso
Publikováno v:
Current Medicinal Chemistry. 30
Abstract: In general, a cancerous process starts from uncontrolled cell growth, apoptosis, and rapid proliferation of cellular clones, as well as, reactive oxygen species (ROS) and imbalance of ROS-antioxidant production also could be involved in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe641a6ec517a14b7c939f1c29f56f79
https://doi.org/10.2174/0929867330666230420152145
https://doi.org/10.2174/0929867330666230420152145