Zobrazeno 1 - 10 of 71 pro vyhledávání: '"Eddy L. Esmans"'
2
Implications of enzymatic, acidic and thermal hydrolysis of DNA on the occurrence of cross-linked melphalan DNA adducts
Autor: Walter Van Dongen, Bart Van den Driessche, Eddy L. Esmans, Filip Lemière, Erwin Witters
Publikováno v: Rapid Communications in Mass Spectrometry. 19:449-454
Calf thymus DNA was treated with melphalan, a nitrogen mustard, and the formation of melphalan cross-linked DNA adducts was investigated. These cross-linked adducts could not be detected either in the enzymatically or in the thermally generated DNA h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::109247c0afe71d1216d7c7671cc11166
https://doi.org/10.1002/rcm.1809
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4
Characterisation of estrone-nucleic acid adducts formed by reaction of 3,4-estrone-o-quinone with 2′-deoxynucleosides/deoxynucleotides using capillary liquid chromatography/electrospray ionization mass spectrometry
Autor: Eddy L. Esmans, Crispina Borges, Jan Embrechts, Walter Van Dongen, Filip Lemière
Publikováno v: Rapid Communications in Mass Spectrometry. 18:2191-2200
Xenobiotic and endobiotic molecules can react with DNA leading to formation of so-called DNA adducts. This modified DNA can be repaired enzymatically, but, if not, these modifications are believed to be responsible for the initiation of carcinogenic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ba98a257b954327112ad76cb3684ac0
https://doi.org/10.1002/rcm.1610
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5
Reactive blue 2 inhibition of cyclic AMP-dependent differentiation of rat C6 glioma cells by purinergic receptor-independent inactivation of phosphatidylinositol 3-kinase
Autor: Daniel Blero, Jean-Pierre Verbelen, Dirk Roymans, Christophe Erneux, Eddy L. Esmans, Kris Vissenberg, Kristof Van Kolen, Patrik Claes, Herman Slegers
Publikováno v: Biochemical Pharmacology. 67:1489-1498
Cyclic AMP-dependent differentiation of rat C6 glioma cells into an astrocyte type II is characterized by inhibition of cell growth and induction of glial fibrillary acidic protein (GFAP) synthesis. Activation of the P2Y(12) receptor with 2-methylthi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c32e51537b8506e1f3b1f847e1c98d37
https://doi.org/10.1016/j.bcp.2003.12.017
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6
Construction of a two-dimensional gel electrophoresis protein database for theNicotiana tabacum cv. Bright Yellow-2 cell suspension culture
Autor: Kris Laukens, Erwin Witters, Eddy L. Esmans, Harry Van Onckelen, Peter Deckers
Publikováno v: Proteomics
Using two-dimensional gel electrophoresis (2-DE) and electrospray-tandem mass spectrometry (ESI-MS/MS), we have started the proteome analysis of the cell line Nicotiana tabacum cv. Bright Yellow-2 (tobacco BY-2). The BY-2 cell suspension culture is w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb7162276f22b41c327b611621f5949e
https://doi.org/10.1002/pmic.200300614
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7
Fast liquid chromatography coupled to electrospray tandem mass spectrometry peptide sequencing for cross-species protein identification
Autor: Kris Laukens, Harry Van Onckelen, Peter Deckers, Walter Van Dongen, Erwin Witters, Eddy L. Esmans
Publikováno v: Rapid communications in mass spectrometry
Using a parallel microcolumn switching liquid chromatography set-up coupled to a quadrupole time-of-flight mass spectrometer, a rapid liquid chromatography/mass spectrometric (LC/MS) protein identification method is presented. Without prior sample cl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4a7961d1a45351742c801ce8dc27206
https://doi.org/10.1002/rcm.1173
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8
Structural studies of benzophenanthridine alkaloid free bases by NMR spectroscopy
Autor: Jiří Dostál, Pavlína Sečkářová, Roger Dommisse, Eddy L. Esmans, Radek Marek
Publikováno v: Magnetic Resonance in Chemistry. 40:147-152
The free bases of eight quaternary benzo[c]phenanthridine alkaloids were investigated by 1H and 13C NMR spectroscopy. The pseudobases (the 6-hydroxy-5,6-dihydro derivatives) were found to be the only products of the alkalization in DMSO-d6 solution.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb50c416c421caca2095b53de6895a77
https://doi.org/10.1002/mrc.979
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9
Equilenin-2′-deoxynucleoside adducts: analysis with nano-liquid chromatography coupled to nano-electrospray tandem mass spectrometry
Autor: Filip Lemière, Walter Van Dongen, Jan Embrechts, Eddy L. Esmans
Publikováno v: Journal of Mass Spectrometry. 36:317-328
The interaction of 4-hydroxy metabolites of estrogens with DNA leads to the formation of DNA adducts. These adducts are believed to play an important role in the incidence of breast and endometrial cancer. In order to be able to analyze these adducts
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8d206b041267d72c0bce141e7863e43f
https://doi.org/10.1002/jms.136
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10
An Ecto-Nucleotide Pyrophosphatase Is One of the Main Enzymes Involved in the Extracellular Metabolism of ATP in Rat C6 Glioma
Autor: Herman Slegers, Bert Grobben, Eddy L. Esmans, Katelijne Anciaux, Mathieu Bollen, Cristiana Stefan, Dirk Roymans
Publikováno v: Journal of neurochemistry
The presence of a nucleotide pyrophosphatase (EC 3.6.1.9) on the plasma membrane of rat C6 glioma has been demonstrated by analysis of the hydrolysis of ATP labeled in the base and in the alpha- and gamma-phosphates. The enzyme degraded ATP into AMP
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698b85a9bde964dfe4742a9725d67689
https://doi.org/10.1046/j.1471-4159.1999.0720826.x
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