Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Eddy, Rijntjes"'
Autor:
Franziska Lademann, Eddy Rijntjes, Josef Köhrle, Elena Tsourdi, Lorenz C. Hofbauer, Martina Rauner
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Hyperthyroidism is a well-known trigger of high bone turnover that can lead to the development of secondary osteoporosis. Previously, we have shown that blocking bone morphogenetic protein (BMP) signaling systemically with BMPR1A-Fc can prev
Externí odkaz:
https://doaj.org/article/8b89a9a3c6184875be917878699170d0
Autor:
Rega H. Kasim, Thilo Samson Chillon, Anna Maria Eleftheriadou, Eddy Rijntjes, Waldemar B. Minich, Stefan Zechmann, Lutz Schomburg
Publikováno v:
Frontiers in Medical Technology, Vol 6 (2024)
ObjectiveGhrelin is an orexigenic peptide that becomes post-translationally modified. Natural autoantibodies to ghrelin (ghrelin-aAb) have been described in healthy subjects, in eating disorders and rheumatic diseases, with potential clinical relevan
Externí odkaz:
https://doaj.org/article/c24445ec719d41e29e47c01a939eed6a
Autor:
Holly Towell, Doreen Braun, Alexander Brol, Andrea di Fonzo, Eddy Rijntjes, Josef Köhrle, Ulrich Schweizer, Clemens Steegborn
Publikováno v:
Biomolecules, Vol 14, Iss 11, p 1373 (2024)
Iodothyronine deiodinases (Dio) are selenocysteine-containing membrane enzymes that activate and inactivate the thyroid hormones (TH) through reductive iodide eliminations. The three deiodinase isoforms are homodimers sharing highly conserved amino a
Externí odkaz:
https://doaj.org/article/907f963ea57340ad810a8e44403b42ad
Autor:
Patricia Gerhardt, Sabine Begall, Caroline Frädrich, Kostja Renko, Thomas B. Hildebrandt, Susanne Holtze, Alexandra Heinrich, Arne Sahm, Xheni Meci, Josef Köhrle, Eddy Rijntjes, Yoshiyuki Henning
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract African mole-rats are subterranean rodents inhabiting underground burrows. This habitat entails risks of overheating, hypoxia, and scarce food availability. Consequently, many subterranean species have evolved low basal metabolism and low bo
Externí odkaz:
https://doaj.org/article/a34ab3b7d48041248e07b0f0681a47e6
Autor:
Kamil Demircan, Sandra Hybsier, Thilo Samson Chillon, Valentin Max Vetter, Eddy Rijntjes, Ilja Demuth, Lutz Schomburg
Publikováno v:
Redox Biology, Vol 65, Iss , Pp 102823- (2023)
Background: Selenium is essential for expression and proper function of a set of redox active selenoproteins implicated in aging-relevant diseases, e.g. type 2 diabetes mellitus (T2D) and hypertension. However, data in cohorts of older adults, partic
Externí odkaz:
https://doaj.org/article/fdd01f5264b7416bb97cb0a4c539516a
Autor:
Tabael L. Turan, Holger J. Klein, Julian Hackler, Livia Hoerner, Eddy Rijntjes, Theresia Reding Graf, Jan A. Plock, Lutz Schomburg
Publikováno v:
Antioxidants, Vol 12, Iss 11, p 1927 (2023)
Oxidative stress, systemic inflammation, and metabolic derangements are hallmarks of burn pathophysiology. Severely burned patients are highly susceptible to infectious complications. Selenium-binding protein 1 (SELENBP1) modulates intracellular redo
Externí odkaz:
https://doaj.org/article/859f315860cb430aa625f2269efc22e8
Autor:
Kostja Renko, Helena Kerp, Janina Pape, Eddy Rijntjes, Tanja Burgdorf, Dagmar Führer, Josef Köhrle
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
In animal studies, both in basic science and in toxicological assessment of potential endocrine disruptors, the state of the thyroid hormone (TH) axis is often described and defined exclusively by the concentrations of circulating THs and TSH. Althou
Externí odkaz:
https://doaj.org/article/9422fa19804b4489ba7aa34a691753cc
Autor:
Kamil Demircan, Ylva Bengtsson, Qian Sun, Annie Brange, Johan Vallon-Christersson, Eddy Rijntjes, Martin Malmberg, Lao H. Saal, Lisa Rydén, Åke Borg, Jonas Manjer, Lutz Schomburg
Publikováno v:
Redox Biology, Vol 47, Iss , Pp 102145- (2021)
The trace element selenium is of essential importance for the synthesis of a set of redox active proteins. We investigated three complementary serum selenium status biomarkers in relation to overall survival and recurrence following diagnosis of prim
Externí odkaz:
https://doaj.org/article/3bf25e52a5e54a0580965ccee461eab2
Publikováno v:
Redox Biology, Vol 37, Iss , Pp 101709- (2020)
Objective: The trace element selenium (Se) is needed for regular biosynthesis of selenoproteins, which contribute to antioxidative defense systems and affect redox-regulated signaling. Elevated Se intake and selenoprotein expression levels have been
Externí odkaz:
https://doaj.org/article/0bd1ecefe48d4a07abca271117bcc1db
Autor:
Sandra Hybsier, Torsten Schulz, Zida Wu, Ilja Demuth, Waldemar B. Minich, Kostja Renko, Eddy Rijntjes, Josef Köhrle, Christian J. Strasburger, Elisabeth Steinhagen-Thiessen, Lutz Schomburg
Publikováno v:
Redox Biology, Vol 11, Iss , Pp 403-414 (2017)
Selenoprotein P (SELENOP) is a liver-derived transporter of selenium (Se) in blood, and a meaningful biomarker of Se status. Se is an essential trace element for the biosynthesis of enzymatically-active selenoproteins, protecting the organism from ox
Externí odkaz:
https://doaj.org/article/77947bd16c4442d998e4dcef848993ba