Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Eddie Yong Jun Tan"'
Autor:
Bing Liang Alvin Chew, An Qi Ngoh, Wint Wint Phoo, Mei Jie Grace Weng, Ho Jun Sheng, Kitti Wing Ki Chan, Eddie Yong Jun Tan, Terri Gelbart, Chenrui Xu, Gene S. Tan, Subhash G. Vasudevan, Dahai Luo
Publikováno v:
npj Viruses, Vol 2, Iss 1, Pp 1-9 (2024)
Abstract Zika virus (ZIKV) belongs to the Flavivirus genus of the Flaviviridae family along with the four serotypes of dengue virus (DENV1–4). The recent global outbreaks of contemporary ZIKV strains demonstrated that infection can lead to neurolog
Externí odkaz:
https://doaj.org/article/05cc657aa26a4a1490e47d3d01fdb81b
Autor:
Qin Gong, Kim Robinson, Chenrui Xu, Phuong Thao Huynh, Kelvin Han Chung Chong, Eddie Yong Jun Tan, Jiawen Zhang, Zhao Zhi Boo, Daniel Eng Thiam Teo, Kenneth Lay, Yaming Zhang, John Soon Yew Lim, Wah Ing Goh, Graham Wright, Franklin L. Zhong, Bruno Reversade, Bin Wu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
NLRP1 and CARD8 are two recently described sensor proteins for the human inflammasome complex. Here, the authors present the cryo-EM CARD filament structures of the NLRP1 and CARD8 activating domains, which reveal how NLRP1 and CARD8 discriminate bet
Externí odkaz:
https://doaj.org/article/fb33e8feb690411b8e3bbd80f9119b57
Autor:
Yaming Zhang, Franklin L. Zhong, Chenrui Xu, Zhao Zhi Boo, Kim S. Robinson, Bruno Reversade, Daniel Eng Thiam Teo, Kenneth Lay, Jiawen Zhang, Graham D. Wright, John Soon Yew Lim, Eddie Yong Jun Tan, Kelvin Han Chung Chong, Wah Ing Goh, Qin Gong, Phuong Thao Huynh, Bin Wu
Publikováno v:
Nature communications, 12(1):188. Nature Publishing Group
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nod-like receptor (NLR) proteins activate pyroptotic cell death and IL-1 driven inflammation by assembling and activating the inflammasome complex. Closely related sensor proteins NLRP1 and CARD8 undergo unique auto-proteolysis-dependent activation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::971fea044a57af53224281deaea2a5a9
https://pure.amc.nl/en/publications/structural-basis-for-distinct-inflammasome-complex-assembly-by-human-nlrp1-and-card8(f93492eb-c2e0-49e8-a33d-9316ae5981a5).html
https://pure.amc.nl/en/publications/structural-basis-for-distinct-inflammasome-complex-assembly-by-human-nlrp1-and-card8(f93492eb-c2e0-49e8-a33d-9316ae5981a5).html
Autor:
Dongli Yu, Wen Song, Eddie Yong Jun Tan, Li Liu, Yu Cao, Jan Jirschitzka, Ertong Li, Elke Logemann, Chenrui Xu, Shijia Huang, Aolin Jia, Xiaoyu Chang, Zhifu Han, Bin Wu, Paul Schulze-Lefert, Jijie Chai
Publikováno v:
Cell. 185:2370-2386.e18
2',3'-cAMP is a positional isomer of the well-established second messenger 3',5'-cAMP, but little is known about the biology of this noncanonical cyclic nucleotide monophosphate (cNMP). Toll/interleukin-1 receptor (TIR) domains of nucleotide-binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::537ef975e5bd6b26fa8d26d42c385c0b
https://doi.org/10.1016/j.cell.2022.04.032
https://doi.org/10.1016/j.cell.2022.04.032