Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Eddie O'Gorman"'
Autor:
Max Dolder, Eddie O'Gorman, Theo Wallimann, Thorsten Hornemann, Dieter Brdiczka, Alex Rück, Michael Eder, Uwe Schlattner
Publikováno v:
BioFactors
BioFactors, Wiley, 1998, 8 (3-4), pp.229-234
BioFactors (Oxford, England)
BioFactors (Oxford, England), 1998, 8 (3-4), pp.229-34
BioFactors, Wiley, 1998, 8 (3-4), pp.229-234
BioFactors (Oxford, England)
BioFactors (Oxford, England), 1998, 8 (3-4), pp.229-34
International audience; Creatine kinase (CK) isoenzymes, specifically located at places of energy demand and energy production, are linked by a phosphocreatine/creatine (PCr/Cr) circuit, found in cells with intermittently high energy demands. Cytosol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5824129c3896b892d0a431c48f49c08
https://doi.org/10.1002/biof.5520080310
https://doi.org/10.1002/biof.5520080310
Publikováno v:
Developmental Neuroscience. 20:469-477
Feeding β-guanidinopropionic acid (GPA), a competitive inhibitor of creatine transport, decreases mortality and increases brain ATP stability in hypoxic mice. To study brain ATP metabolism in GPA-fed animals, respiratory rates were measured in grey
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3768f53276fde2e2f3ba9e09e0574d95
https://doi.org/10.1159/000017345
https://doi.org/10.1159/000017345
Autor:
Eddie O'Gorman, Alan P. Koretsky, Max Dolder, Dieter Brdiczka, Theo Wallimann, Giesela Beutner
Publikováno v:
FEBS Letters. 414:253-257
Cyclosporin A sensitive swelling of mitochondria isolated from control mouse livers and from the livers of transgenic mice expressing human ubiquitous mitochondrial creatine kinase occurred in the presence of both 40 microM calcium and 5 microM atrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6084256a8bd3acfddeb1ebb64a7ce5df
https://doi.org/10.1016/s0014-5793(97)01045-4
https://doi.org/10.1016/s0014-5793(97)01045-4
Publikováno v:
Detection of Mitochondrial Diseases ISBN: 9781461378006
Mitochondrial inclusion bodies are often described in skeletal muscle of patients suffering diseases termed mitochondrial myopathies. A major component of these structures was discovered as being mitochondrial creatine kinase. Similar creatine kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b818040220dadabcb45304ecb59e41f
https://doi.org/10.1007/978-1-4615-6111-8_44
https://doi.org/10.1007/978-1-4615-6111-8_44
Publikováno v:
Biochimica et biophysica acta. 1276(2)
Guanidinopropionic acid (GPA), an analogue of creatine (Cr), is known to inhibit Cr uptake by cells. The metabolic effects of chronic Cr depletion on brain, heart and soleus muscle of rats were studied. In GPA hearts and soleus muscle, total specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7a3027da58fa1085deaa60c1c6c3160
https://pubmed.ncbi.nlm.nih.gov/8816948
https://pubmed.ncbi.nlm.nih.gov/8816948
Publikováno v:
ResearcherID
Rats were fed a 2% guanidino propionic acid diet for up to 18 weeks to induce cellular creatine depletion by inhibition of creatine uptake by this creatine analogue. Ultrastructural analysis of creatine depleted tissues showed that mitochondrial inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccf8e57bda7444991844ba1e6a546ca4
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1997XG95000007&KeyUID=WOS:A1997XG95000007
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1997XG95000007&KeyUID=WOS:A1997XG95000007