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Akademický článek

Phase II randomized trial of a non-steroidal mouth wash for prevention and treatment of stomatitis in women with hormone receptor positive breast cancer treated with everolimus

Autor: Parvin F. Peddi, Merry Tetef, Paul Coluzzi, Karo K. Arzoo, Eddie H. Hu, Maurice J. Berkowitz, David Chan, Dennis Moore, Brad Adams, Xiaoyan Wang, Sara A. Hurvitz

Publikováno v: Therapeutic Advances in Medical Oncology, Vol 12 (2020)

Background: Stomatitis is a frequent dose limiting toxicity of everolimus, an approved therapy for patients with metastatic breast cancer. No randomized trials of a prophylactic measure to prevent mucositis have been reported. Methods: We conducted a

Externí odkaz: https://doaj.org/article/75c6ea8cccd543f2944ff91e58816f0f

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Spontaneous hematoma of the thigh associated with antiproteinase-3 antibody in a patient with metastatic squamous cell carcinoma treated with nivolumab

Autor: Eddie H. Hu, Yi-Kong Keung

Publikováno v: Journal of Oncology Pharmacy Practice. 25:1261-1264

We report an unusual case of spontaneous intramuscular hematoma associated with antiproteinase 3 antibody in a patient with metastatic squamous cell carcinoma receiving nivolumab and the medical literature is reviewed.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ab3fde45522221c32ed8eb73b091b9
https://doi.org/10.1177/1078155218786352

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Acute myeloid leukemia with complex cytogenetic abnormalities associated with long-term use of oral colloidal silver as nutritional supplement - Case report and review of literature

Autor: Tina Wang, Eddie H. Hu, Yi-Kong Keung

Publikováno v: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners. 26(1)

We report a case of acute myeloid leukemia with complex cytogenetic abnormalities suggestive of preexisting myelodysplastic syndrome in a patient with habitual ingestion of colloidal silver as nutritional supplement for over 10 years and the medical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db527c9fd1ede0dc9e3305716ab666a9
https://pubmed.ncbi.nlm.nih.gov/30854923

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Phase Ib/II single-arm trial evaluating the combination of everolimus, lapatinib and capecitabine for the treatment of HER2-positive breast cancer with brain metastases (TRIO-US B-09)

Autor: Ivana Meglar, Rena Callahan, Eddie H. Hu, Xiaoyan Wang, Aurelio Castrellon, Dennis J. Slamon, Jonathan Berkowitz, B DiCarlo, Rashi Singh, R Dichmann, Brad Adams, Aruna Mani, Ira S. Smalberg, Julie Taguchi, Diego Martinez, Evthokia A Hobbs, David Chan, Sara A. Hurvitz

Publikováno v: Therapeutic Advances in Medical Oncology
Therapeutic Advances in Medical Oncology, Vol 10 (2018)

Background:Improving outcomes for patients with human epidermal growth factor 2-positive (HER2+) central nervous system (CNS) metastases remains an unmet clinical need. This trial evaluated a novel combination of everolimus, lapatinib and capecitabin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bde9e0c80fda5fea0455e9bc97f62647
https://pubmed.ncbi.nlm.nih.gov/30542377

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A case of recurrent pancytopenia in a patient with acute promyelocytic leukemia on maintenance chemotherapy and concomitant methyltetrahydrofolate reductase and thiopurine S-methyltransferase mutation - review of literature

Autor: Eddie H. Hu, Lap-Woon Keung, Yi-Kong Keung

Publikováno v: Journal of Oncology Pharmacy Practice. 22:548-551

Pharmacogenetics is a study of how genetic variation of an individual affects the drug response. We report a case of recurrent pancytopenia resulting from maintenance chemotherapy in a patient with acute promyelocytic leukemia and two pharmacogenetic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4605a8cfe703d6d1cc58e6639f35de99
https://doi.org/10.1177/1078155215577235

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Randomized Comparison of Every-2-Week Darbepoetin Alfa and Weekly Epoetin Alfa for the Treatment of Chemotherapy-Induced Anemia: The 20030125 Study Group Trial

Autor: Linda D. Bosserman, Eddie H. Hu, G. Rossi, John A. Glaspy, Richard E. Lloyd, Ravi Patel, Saroj Vadhan-Raj, Dianne Tomita, Ralph V. Boccia

Publikováno v: Journal of Clinical Oncology. 24:2290-2297

Purpose Chemotherapy-induced anemia is widely treated in the United States with darbepoetin alfa (DA) or epoetin alfa (EA). This noninferiority study systematically compares efficacy and safety of DA and EA using common doses and schedules used in cl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1b7f119b0528a5acb041f00c884ee4f2
https://doi.org/10.1200/jco.2005.03.8570

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A phase II trial of docetaxel with bevacizumab as first-line therapy for HER2-negative metastatic breast cancer (TORI B01)

Autor: Lii-Shin Lin, Rebecca L. Moroose, Steven H. Applebaum, Giribala Patel, Nancy Ryba, Dennis J. Slamon, Christopher T Hagenstad, Sara A. Hurvitz, Heather Allen, Fairooz F. Kabbinavar, Eddie H. Hu, David Chan, He-Jing Wang, John A. Glaspy

Publikováno v: Clinical breast cancer. 10(4)

Introduction Addition of the antiangiogenic agent bevacizumab to paclitaxel significantly improves response rates and progression-free survival for metastatic breast cancer (MBC). To assess the activity of docetaxel plus bevacizumab, a multicenter ph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b96a36ea141057342076a3a2b4904466
https://pubmed.ncbi.nlm.nih.gov/20705564

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Panitumumab with irinotecan/leucovorin/5-fluorouracil for first-line treatment of metastatic colorectal cancer

Autor: Liqiang Yang, Imtiaz Malik, Eddie H. Hu, David Chan, Rafael G. Amado, Simon Tchekmedyian, J. Randolph Hecht, Jordan Berlin, James Posey

Publikováno v: Clinical colorectal cancer. 6(6)

Purpose Panitumumab is a fully human monoclonal antibody directed against the epidermal growth factor receptor and is indicated for patients with metastatic colorectal cancer (mCRC) who have experienced disease progression after standard chemotherapy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac840c22b87ef6193c3b0fb2af80a2c
https://pubmed.ncbi.nlm.nih.gov/17531105

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Phase II study of docetaxel (D) plus bevacizumab (B) in Her/2 negative metastatic breast carcinoma (MBC)

Autor: C. Gottlieb, G. Patel, David M. Reese, Eddie H. Hu, David W. Chan, Fairooz F. Kabbinavar, J. Sosa, A. Wax, H. Allen, Dennis J. Slamon

Publikováno v: Journal of Clinical Oncology. 24:13047-13047

13047 Background: Taxol+Bevacizumab (B) has clinical activity in Her/2 negative chemotherapy naive MBC with a PFS (11.4 mo), RR (29.9%), and OS (28.4 mo). We are conducting a single arm Phase 2 trial to assess the efficacy of Docetaxel (D)+B. Primary

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f8efb67d8e466b0159d9347f5c8641e7
https://doi.org/10.1200/jco.2006.24.18_suppl.13047

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