Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Edda Adler-Graschinsky"'
Publikováno v:
International Journal of Hypertension, Vol 2012 (2012)
In rat isolated mesenteric beds that were contracted with NA as an in vitro model of the vascular adrenergic hyperactivity that usually precedes the onset of primary hypertension, the oral administration (3 daily doses) of either 10 mg/kg genistein o
Externí odkaz:
https://doaj.org/article/64abb39679ee4a40942d02f347fd6792
Publikováno v:
European Journal of Pharmacology. 610:75-80
The intrathecal (i.t.) injection of 50 and 100 nmol anandamide to urethane anesthetized rats induced a dose-dependent decrease in the mean blood pressure (-10.6+/-1.6 mmHg and -15.0+/-1.7 mmHg, respectively; n=6) whereas a lower dose of this endocann
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baff6a50585630a02353abdde6691a1f
https://doi.org/10.1016/j.ejphar.2009.03.021
https://doi.org/10.1016/j.ejphar.2009.03.021
Publikováno v:
British Journal of Pharmacology. 151:427-440
In addition to their classical known effects, such as analgesia, impairment of cognition and learning and appetite enhancement, cannabinoids have also been related to the regulation of cardiovascular responses and implicated in cardiovascular patholo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cfdec6a2dc88638fed79e9eb8d5591b
https://doi.org/10.1038/sj.bjp.0707261
https://doi.org/10.1038/sj.bjp.0707261
Autor:
María Laura Ribeiro, Tamara Abramoff, Roxana N. Peroni, Ana Maria Franchi, Edda Adler-Graschinsky, Marı́a Luz Orliac
Publikováno v:
European Journal of Pharmacology. 557:49-57
The in vitro exposure to anandamide elicits greater relaxations in mesenteric beds isolated from female compared to male rats. The present work shows that in mesenteric beds precontracted with noradrenaline the removal of endothelium increased the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e152dc50180cc15915176844b5afb06
https://doi.org/10.1016/j.ejphar.2006.11.012
https://doi.org/10.1016/j.ejphar.2006.11.012
Autor:
Marı́a Luz Orliac, Inés Poblete, René Briones, Edda Adler-Graschinsky, J. Pablo Huidobro-Toro
Publikováno v:
The Journal of Physiology. 568:539-551
In the isolated rat mesenteric bed, the 1 min perfusion with 100 nm anandamide, a concentration that did not evoke vasorelaxation, elicited an acute release of 165.1 ± 9.2 pmol nitric oxide (NO) that was paralleled by a 2-fold increase in cGMP tissu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf8ad2a42c3a91236bd7f13c460c454c
https://doi.org/10.1113/jphysiol.2005.094292
https://doi.org/10.1113/jphysiol.2005.094292
Autor:
Roxana N. Peroni, Damasia Becu-Villalobos, Stella Maris Celuch, Juan Pablo Huidobro-Toro, Edda Adler-Graschinsky, Marı́a Luz Orliac
Publikováno v:
European Journal of Pharmacology. 493:151-160
Anandamide (0.01 to 10 microM) caused greater concentration-dependent reductions of the contractile-induced responses to noradrenaline in female than in male mesenteric vascular beds isolated from adult Sprague-Dawley rats. Greater relaxant responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f25b99d8a0437b1e09b989f2de5483b5
https://doi.org/10.1016/j.ejphar.2004.04.031
https://doi.org/10.1016/j.ejphar.2004.04.031
Publikováno v:
Current Vascular Pharmacology. 1:301-313
Although cannabinoids have been recreationally employed for thousands of years, it was not until the discovery of their specific receptors, in the early nineties, that the molecular basis of cannabinoid activity have began to be understood. Growing r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44612aa726658e176fb025a18b1885f0
https://doi.org/10.2174/1570161033476583
https://doi.org/10.2174/1570161033476583
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 368:270-276
This study examined the effect of intrathecal (i.t.) injection of the endocannabinoid anandamide in urethane-anesthetized rats. The tip of the i.t. cannula was positioned at the T12–L1 level of the spinal cord. Either anandamide or its metabolicall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea47fceca8eec38d5938b46be5d7f83
https://doi.org/10.1007/s00210-003-0800-x
https://doi.org/10.1007/s00210-003-0800-x
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 304:179-184
The aim of the present experiments was to study the effects of exogenously added anandamide on transient norepinephrine (NE)-induced contractions in mesenteric beds isolated from adult male Sprague-Dawley rats 6 h after the i.p. administration of 5 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b54fccdc087bade9c778cfffb34b1ca5
https://doi.org/10.1124/jpet.102.041095
https://doi.org/10.1124/jpet.102.041095
Autor:
Xavier F. Figueroa, M. Inés Poblete, Victoria E Mendizábal, Edda Adler-Graschinsky, Mauricio P. Boric, J. Pablo Huidobro-Toro
Publikováno v:
British Journal of Pharmacology. 134:957-968
1. To assess the involvement of endothelial alpha(2)-adrenoceptors in the clonidine-induced vasodilatation, the mesenteric artery of Sprague Dawley rats was cannulated and perfused with Tyrode solution (2 ml min(-1)). We measured perfusion pressure,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d031429674865ab3f81ff8e2dd88582
https://doi.org/10.1038/sj.bjp.0704320
https://doi.org/10.1038/sj.bjp.0704320