Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Edda, Blümel"'
Autor:
Rainer Knoll, Lorenzo Bonaguro, Jéssica C. dos Santos, Stefanie Warnat-Herresthal, Maartje C. P. Jacobs-Cleophas, Edda Blümel, Nico Reusch, Arik Horne, Miriam Herbert, Melanie Nuesch-Germano, Twan Otten, Wouter A. van der Heijden, Lisa van de Wijer, Alex K. Shalek, Kristian Händler, Matthias Becker, Marc D. Beyer, Mihai G. Netea, Leo A. B. Joosten, Andre J. A. M. van der Ven, Joachim L. Schultze, Anna C. Aschenbrenner
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionPeople living with HIV (PLHIV) are characterized by functional reprogramming of innate immune cells even after long-term antiretroviral therapy (ART). In order to assess technical feasibility of omics technologies for application to large
Externí odkaz:
https://doaj.org/article/3678944685db4f8eaf7e3cde8146b3e4
Autor:
Edda Blümel, Shamaila Munir Ahmad, Claudia Nastasi, Andreas Willerslev-Olsen, Maria Gluud, Simon Fredholm, Tengpeng Hu, Bas G. J. Surewaard, Lise M. Lindahl, Hanne Fogh, Sergei B. Koralov, Lise Mette Rahbek Gjerdrum, Rachael A. Clark, Lars Iversen, Thorbjørn Krejsgaard, Charlotte Menné Bonefeld, Carsten Geisler, Jürgen C. Becker, Anders Woetmann, Mads Hald Andersen, Terkild Brink Buus, Niels Ødum
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Staphylococcus aureus and its toxins have been linked to disease progression and mortality in advanced stages of cutaneous T-cell lymphoma (CTCL). CD8+ T cells play a crucial role in anti-cancer responses and high CD8+ T cell numbers in tumor lesions
Externí odkaz:
https://doaj.org/article/188b539afb7847da86837b09e61b44e5
Autor:
Terkild Brink Buus, Andreas Willerslev-Olsen, Simon Fredholm, Edda Blümel, Claudia Nastasi, Maria Gluud, Tengpeng Hu, Lise M. Lindahl, Lars Iversen, Hanne Fogh, Robert Gniadecki, Ivan V. Litvinov, Jenny L. Persson, Charlotte Menné Bonefeld, Carsten Geisler, Jan Pravsgaard Christensen, Thorbjørn Krejsgaard, Thomas Litman, Anders Woetmann, Niels Ødum
Publikováno v:
Blood Advances, Vol 2, Iss 16, Pp 2115-2126 (2018)
Abstract: Sézary syndrome (SS) is an aggressive leukemic variant of cutaneous T-cell lymphoma (CTCL) with a median life expectancy of less than 4 years. Although initial treatment responses are often good, the vast majority of patients with SS fail
Externí odkaz:
https://doaj.org/article/b5af0c4ccff540ba900bbbaf4eed2d20
Autor:
Edda Blümel, Andreas Willerslev-Olsen, Maria Gluud, Lise M. Lindahl, Simon Fredholm, Claudia Nastasi, Thorbjørn Krejsgaard, Bas G. J. Surewaard, Sergei B. Koralov, Tengpeng Hu, Jenny L. Persson, Charlotte Menné Bonefeld, Carsten Geisler, Lars Iversen, Jürgen C. Becker, Mads Hald Andersen, Anders Woetmann, Terkild Brink Buus, Niels Ødum
Publikováno v:
OncoImmunology, Vol 8, Iss 11 (2019)
Staphylococcus aureus is implicated in disease progression in cutaneous T-cell lymphoma (CTCL). Here, we demonstrate that malignant T cell lines derived from CTCL patients as well as primary malignant CD4+ T cells from Sézary syndrome patients are c
Externí odkaz:
https://doaj.org/article/85e3c47951f844e3992b9edf776ee97d
Autor:
Maria Gluud, Emil M. H. Pallesen, Terkild B. Buus, Lise Mette Rahbek Gjerdrum, Lise M. Lindahl, Maria R. Kamstrup, Michael Bzorek, Maria Danielsen, Rikke Bech, Madalena N. Monteiro, Edda Blümel, Andreas Willerslev-Olsen, Anders Lykkebo-Valløe, Chella Krishna Vadivel, Thorbjørn Krejsgaard, Charlotte Menne Bonefeld, Carsten Geisler, Jürgen C. Becker, Sergei B. Koralov, Lars Iversen, Thomas Litman, Anders Woetmann, Niels Ødum
Publikováno v:
Gluud, M, Pallesen, E M H, Buus, T B, Gjerdrum, L M R, Lindahl, L M, Kamstrup, M R, Bzorek, M, Danielsen, M, Bech, R, Monteiro, M N, Blümel, E, Willerslev-Olsen, A, Lykkebo-Velløe, A, Vadivel, C K, Krejsgaard, T, Bonefeld, C M, Geisler, C, Becker, J C, Koralov, S B, Iversen, L, Litman, T, Woetmann, A & Odum, N 2023, ' Malignant T cells induce skin barrier defects through cytokine-mediated JAK/STAT signalling in cutaneous T-cell lymphoma ', Blood, vol. 141, no. 2, pp. 180-193 . https://doi.org/10.1182/blood.2022016690
Cutaneous T-cell lymphoma (CTCL) is a devastating lymphoid malignancy characterized by the accumulation of malignant T cells in the dermis and epidermis. Skin lesions cause serious symptoms that hamper quality of life and are entry sites for bacteria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d68ea73b9c4d3ba82e54ed4ff179d49
https://pure.au.dk/portal/da/publications/malignant-t-cells-induce-skin-barrier-defects-through-cytokinemediated-jakstat-signalling-in-cutaneous-tcell-lymphoma(180c34ab-2f3b-4c77-ae70-3d55bf91a48d).html
https://pure.au.dk/portal/da/publications/malignant-t-cells-induce-skin-barrier-defects-through-cytokinemediated-jakstat-signalling-in-cutaneous-tcell-lymphoma(180c34ab-2f3b-4c77-ae70-3d55bf91a48d).html
Autor:
Mariusz A. Wasik, Thorbjørn Krejsgaard, Maria Gluud, Charlotte M. Bonefeld, Carsten Geisler, Edda Blümel, Jürgen C. Becker, Andreas Willerslev-Olsen, Ivan V. Litvinov, Niels Ødum, Claudia Nastasi, Lars Iversen, Lise M. Lindahl, Lise Mette Rahbek Gjerdrum, Terkild B. Buus, Thomas Litman, Maarten H. Vermeer, Mads Hald Andersen, Anders Woetmann
Publikováno v:
Blood Cancer Journal, Vol 10, Iss 5, Pp 1-11 (2020)
Willerslev-Olsen, A, Buus, T B, Nastasi, C, Blümel, E, Gluud, M, Bonefeld, C M, Geisler, C, Lindahl, L M, Vermeer, M, Wasik, M A, Iversen, L, Becker, J C, Andersen, M H, Gjerdrum, L M R, Litvinov, I V, Litman, T, Krejsgaard, T, Woetmann, A & Ødum, N 2020, ' Staphylococcus aureus enterotoxins induce FOXP3 in neoplastic T cells in Sézary syndrome ', Blood Cancer Journal, vol. 10, no. 5, 57 . https://doi.org/10.1038/s41408-020-0324-3
Willerslev-Olsen, A, Buus, T B, Nastasi, C, Blümel, E, Gluud, M, Bonefeld, C M, Geisler, C, Lindahl, L M, Vermeer, M, Wasik, M A, Iversen, L, Becker, J C, Andersen, M H, Gjerdrum, L M R, Litvinov, I V, Litman, T, Krejsgaard, T, Woetmann, A & Ødum, N 2020, ' Staphylococcus aureus enterotoxins induce FOXP3 in neoplastic T cells in Sézary syndrome ', Blood Cancer Journal, vol. 10, no. 5, pp. 57 . https://doi.org/10.1038/s41408-020-0324-3
Blood Cancer Journal
Blood Cancer Journal, 10(5). NATURE PUBLISHING GROUP
Willerslev-Olsen, A, Buus, T B, Nastasi, C, Blümel, E, Gluud, M, Bonefeld, C M, Geisler, C, Lindahl, L M, Vermeer, M, Wasik, M A, Iversen, L, Becker, J C, Andersen, M H, Gjerdrum, L M R, Litvinov, I V, Litman, T, Krejsgaard, T, Woetmann, A & Ødum, N 2020, ' Staphylococcus aureus enterotoxins induce FOXP3 in neoplastic T cells in Sézary syndrome ', Blood Cancer Journal, vol. 10, no. 5, 57 . https://doi.org/10.1038/s41408-020-0324-3
Willerslev-Olsen, A, Buus, T B, Nastasi, C, Blümel, E, Gluud, M, Bonefeld, C M, Geisler, C, Lindahl, L M, Vermeer, M, Wasik, M A, Iversen, L, Becker, J C, Andersen, M H, Gjerdrum, L M R, Litvinov, I V, Litman, T, Krejsgaard, T, Woetmann, A & Ødum, N 2020, ' Staphylococcus aureus enterotoxins induce FOXP3 in neoplastic T cells in Sézary syndrome ', Blood Cancer Journal, vol. 10, no. 5, pp. 57 . https://doi.org/10.1038/s41408-020-0324-3
Blood Cancer Journal
Blood Cancer Journal, 10(5). NATURE PUBLISHING GROUP
Sézary syndrome (SS) is a heterogeneous leukemic subtype of cutaneous T-cell lymphoma (CTCL) with generalized erythroderma, lymphadenopathy, and a poor prognosis. Advanced disease is invariably associated with severe immune dysregulation and the maj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2e53b5a808b364a65c6ba5a71a5a6a1
http://link.springer.com/article/10.1038/s41408-020-0324-3
http://link.springer.com/article/10.1038/s41408-020-0324-3
Autor:
Pieter Spee, Terkild B. Buus, Andreas Hald, Maria Gluud, Thorbjørn Krejsgaard, Claudia Nastasi, Andreas Willerslev-Olsen, Niels Ødum, Lise Mette Rahbek Gjerdrum, Edda Blümel, Jens Eriksen, Pia Rude Nielsen, Anders Woetmann, Anneline Nansen, Tengpeng Hu, Michael Bzorek
Publikováno v:
Dermatology. 236:123-132
Background: The voltage-gated potassium channel Kv1.3 (KCNA3) is expressed by effector memory T cells (TEM) and plays an important role in their activation and proliferation. Mycosis fungoides (MF), the most common subtype of cutaneous T-cell lymphom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57dd3fa40df5924eff1f862c09347cf5
https://doi.org/10.1159/000502137
https://doi.org/10.1159/000502137
Autor:
Thorbjørn Krejsgaard, Niels Ødum, Mads Hald Andersen, Veronica Stolearenco, Özcan Met, David L. Petersen, Pieter Spee, Terkild B. Buus, Andreas Willerslev-Olsen, Thomas Litman, Per thor Straten, Tengpeng Hu, Simon Fredholm, Lise Mette Rahbek Gjerdrum, Anders Woetmann, Edda Blümel, Anneline Nansen, Hanne Fogh, Maria Gluud, Robert Gniadecki, Betina Kerstin Lundholt, Claudia Nastasi, Madalena N Monteiro
Publikováno v:
Oncotarget
Hu, T, Buus, T B, Krejsgaard, T, Nansen, A, Lundholt, B K, Spee, P, Fredholm, S, Petersen, D L, Blümel, E, Gluud, M, Monteiro, M N, Willerslev-Olsen, A, Andersen, M H, Straten, P T, Met, Ö, Stolearenco, V, Fogh, H, Gniadecki, R, Nastasi, C, Litman, T, Woetmann, A, Gjerdrum, L M R & Ødum, N 2019, ' Expression and function of Kv1.3 channel in malignant T cells in Sézary syndrome ', OncoTarget, vol. 10, no. 47, pp. 4894-4906 . https://doi.org/10.18632/oncotarget.27122
Hu, T, Buus, T B, Krejsgaard, T, Nansen, A, Lundholt, B K, Spee, P, Fredholm, S, Petersen, D L, Blümel, E, Gluud, M, Monteiro, M N, Willerslev-Olsen, A, Andersen, M H, Straten, P T, Met, Ö, Stolearenco, V, Fogh, H, Gniadecki, R, Nastasi, C, Litman, T, Woetmann, A, Gjerdrum, L M R & Ødum, N 2019, ' Expression and function of Kv1.3 channel in malignant T cells in Sézary syndrome ', OncoTarget, vol. 10, no. 47, pp. 4894-4906 . https://doi.org/10.18632/oncotarget.27122
The voltage-gated potassium channel Kv1.3 (KCNA3) is expressed by a subset of chronically activated memory T cells and plays an important role in their activation and proliferation. Here, we show that primary malignant T cells isolated from patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963263f835fea8037212a6bd57ee4f1e
http://europepmc.org/articles/PMC6690676
http://europepmc.org/articles/PMC6690676
Autor:
Niels Ødum, Edda Blümel, Thorbjørn Krejsgaard, Simon Fredholm, Terkild B. Buus, Claudia Nastasi, Anders Woetmann, Andreas Willerslev-Olsen, Lars Iversen, Carsten Geisler, Maria Gluud, Charlotte M. Bonefeld, Lise M. Lindahl, Thomas Litman
Publikováno v:
Gluud, M, Fredholm, S, Blümel, E, Willerslev-Olsen, A, Buus, T B, Nastasi, C, Krejsgaard, T, Bonefeld, C M, Woetmann, A, Iversen, L, Litman, T, Geisler, C, Ødum, N & Lindahl, L M 2021, ' MicroRNA-93 Targets p21 and Promotes Proliferation in Mycosis Fungoides T Cells ', Dermatology, vol. 237, no. 2, pp. 277-282 . https://doi.org/10.1159/000505743
Background: Mycosis fungoides (MF), the most common form of cutaneous T-cell lymphoma (CTCL), is a lymphoproliferative disorder characterized by proliferation of malignant T cells in a chronic inflammatory environment in the skin. The nature of MF is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc07428c4152162475112c6c9be92f68
https://pure.au.dk/portal/da/publications/microrna93-targets-p21-and-promotes-proliferation-in-mycosis-fungoides-t-cells(62144376-994c-4ee2-a8d8-762b044b137f).html
https://pure.au.dk/portal/da/publications/microrna93-targets-p21-and-promotes-proliferation-in-mycosis-fungoides-t-cells(62144376-994c-4ee2-a8d8-762b044b137f).html
Autor:
Niels Ødum, Sergei B. Koralov, Bas G.J. Surewaard, Thorbjørn Krejsgaard, Terkild B. Buus, Lise M. Lindahl, Shamaila Munir Ahmad, Claudia Nastasi, Anders Woetmann, Lise Mette Rahbek Gjerdrum, Rachael A. Clark, Andreas Willerslev-Olsen, Lars Iversen, Tengpeng Hu, Simon Fredholm, Jürgen C. Becker, Mads Hald Andersen, Carsten Geisler, Edda Blümel, Hanne Fogh, Charlotte M. Bonefeld, Maria Gluud
Publikováno v:
Blümel, E, Munir Ahmad, S, Nastasi, C, Willerslev-Olsen, A, Gluud, M, Fredholm, S, Hu, T, Surewaard, B G J, Lindahl, L M, Fogh, H, Koralov, S B, Rahbek Gjerdrum, L M, Clark, R A, Iversen, L, Krejsgaard, T, Bonefeld, C M, Geisler, C, Becker, J C, Woetmann, A, Andersen, M H, Buus, T B & Ødum, N 2020, ' Staphylococcus aureus alpha-toxin inhibits CD8 + T cell-mediated killing of cancer cells in cutaneous T-cell lymphoma ', OncoImmunology, vol. 9, no. 1, 1751561 . https://doi.org/10.1080/2162402X.2020.1751561
OncoImmunology, Vol 9, Iss 1 (2020)
Blümel, E, Munir Ahmad, S, Nastasi, C, Willerslev-Olsen, A, Gluud, M, Fredholm, S, Hu, T, Surewaard, B G J, Lindahl, L M, Fogh, H, Koralov, S B, Rahbek Gjerdrum, L M, Clark, R A, Iversen, L, Krejsgaard, T, Bonefeld, C M, Geisler, C, Becker, J C, Woetmann, A, Andersen, M H, Buus, T B & Ødum, N 2020, ' Staphylococcus aureus alpha-toxin inhibits CD8+ T cell-mediated killing of cancer cells in cutaneous T-cell lymphoma ', OncoImmunology, vol. 9, no. 1, pp. 1751561 . https://doi.org/10.1080/2162402X.2020.1751561
Oncoimmunology
OncoImmunology, Vol 9, Iss 1 (2020)
Blümel, E, Munir Ahmad, S, Nastasi, C, Willerslev-Olsen, A, Gluud, M, Fredholm, S, Hu, T, Surewaard, B G J, Lindahl, L M, Fogh, H, Koralov, S B, Rahbek Gjerdrum, L M, Clark, R A, Iversen, L, Krejsgaard, T, Bonefeld, C M, Geisler, C, Becker, J C, Woetmann, A, Andersen, M H, Buus, T B & Ødum, N 2020, ' Staphylococcus aureus alpha-toxin inhibits CD8+ T cell-mediated killing of cancer cells in cutaneous T-cell lymphoma ', OncoImmunology, vol. 9, no. 1, pp. 1751561 . https://doi.org/10.1080/2162402X.2020.1751561
Oncoimmunology
Staphylococcus aureus and its toxins have been linked to disease progression and mortality in advanced stages of cutaneous T-cell lymphoma (CTCL). CD8+ T cells play a crucial role in anti-cancer responses and high CD8+ T cell numbers in tumor lesions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c227141dd13596568b5954a415b5d59d
https://curis.ku.dk/ws/files/243011890/Staphylococcus_aureus_alpha_toxin_inhibits_CD8_T_cell_mediated_killing_of_cancer_cells_in_cutaneous_T_cell_lymphoma.pdf
https://curis.ku.dk/ws/files/243011890/Staphylococcus_aureus_alpha_toxin_inhibits_CD8_T_cell_mediated_killing_of_cancer_cells_in_cutaneous_T_cell_lymphoma.pdf