Expert-Augmented Computational Drug Repurposing Identified Baricitinib as a Treatment for COVID-19

Autor: Daniel P. Smith, Olly Oechsle, Michael J. Rawling, Ed Savory, Alix M.B. Lacoste, Peter John Richardson

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

The onset of the 2019 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic necessitated the identification of approved drugs to treat the disease, before the development, approval and widespread administration of suitable vaccines. T

Externí odkaz: https://doaj.org/article/2fbc02dfda9d46a5b1da373a8184b9af

"Pure by NMR"?

Autor: Claridge TD; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK., Davies SG, Polywka ME, Roberts PM, Russell AJ, Savory ED, Smith AD

Publikováno v: Organic letters [Org Lett] 2008 Dec 04; Vol. 10 (23), pp. 5433-6.

Kinetic resolution and parallel kinetic resolution of methyl (+/-)-5-alkyl-cyclopentene-1-carboxylates for the asymmetric synthesis of 5-alkyl-cispentacin derivatives.

Autor: Davies SG; Department of Organic Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, UK OX1 3TA. steve.davies@chem.ox.ac.uk, Garner AC, Long MJ, Morrison RM, Roberts PM, Savory ED, Smith AD, Sweet MJ, Withey JM

Publikováno v: Organic & biomolecular chemistry [Org Biomol Chem] 2005 Aug 07; Vol. 3 (15), pp. 2762-75. Date of Electronic Publication: 2005 Jun 30.

Asymmetric synthesis of substituted 1-aminocyclopropane-1-carboxylic acids via diketopiperazine methodology.

Autor: Buñuel E; Dyson Perrins Laboratory, University of Oxford, South Parks Road, Oxford, UK OX1 3QY., Bull SD, Davies SG, Garner AC, Savory ED, Smith AD, Vickers RJ, Watkin DJ

Publikováno v: Organic & biomolecular chemistry [Org Biomol Chem] 2003 Jul 21; Vol. 1 (14), pp. 2531-42.