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Efficacy and Safety of Single and Multiple Doses of a Fixed-dose Combination of Ibuprofen and Acetaminophen in the Treatment of Postsurgical Dental Pain

Autor: David Kellstein, Mario Cruz-Rivera, Ed Paluch, Derek Muse, Shawn Searle, Elizabeth DePadova, Rina Leyva

Publikováno v: The Clinical Journal of Pain. 36:495-504

A previous pilot study demonstrated that various fixed-dose combinations (FDCs) of ibuprofen (IBU) and acetaminophen (APAP) provided analgesic efficacy comparable to a higher dose of IBU, with the same safety profile. These studies further evaluated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6db03e24d84ed29c01b8155f7070b3cc
https://doi.org/10.1097/ajp.0000000000000828

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Analgesic Efficacy of a New Immediate-Release/Extended-Release Formulation of Ibuprofen: Results From Single- and Multiple-Dose Postsurgical Dental Pain Studies

Autor: Steven E. Christensen, Suzanne Meeves, Stephen E. Daniels, Ed Paluch, Shyamalie Jayawardena

Publikováno v: Clinical Pharmacology in Drug Development

Analgesic effects of ibuprofen immediate‐release/extended‐release (IR/ER) 600‐mg tablets were evaluated in 2 randomized, double‐blind, placebo‐controlled dental pain studies. Patients 16–40 years old with moderate–severe pain following

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66932feeab43c144a126d7731949de7d
https://doi.org/10.1002/cpdd.297

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