Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Ed Luk"'
Autor:
Anand Ranjan, Vu Q Nguyen, Sheng Liu, Jan Wisniewski, Jee Min Kim, Xiaona Tang, Gaku Mizuguchi, Ejlal Elalaoui, Timothy J Nickels, Vivian Jou, Brian P English, Qinsi Zheng, Ed Luk, Luke D Lavis, Timothee Lionnet, Carl Wu
Publikováno v:
eLife, Vol 9 (2020)
The H2A.Z histone variant, a genome-wide hallmark of permissive chromatin, is enriched near transcription start sites in all eukaryotes. H2A.Z is deposited by the SWR1 chromatin remodeler and evicted by unclear mechanisms. We tracked H2A.Z in living
Externí odkaz:
https://doaj.org/article/68623bc3e237447ba32f6afbac61397c
Publikováno v:
Cell Reports, Vol 30, Iss 1, Pp 257-268.e5 (2020)
Summary: In preparation for transcription, the chromatin remodeler SWR installs homotypic ZZ nucleosomes at promoters by replacing the two nucleosomal H2A with H2A.Z in a stepwise manner. Nucleosome-free regions (NFRs) help recruit SWR to promoters;
Externí odkaz:
https://doaj.org/article/7e1c01f81c364ad3aa00a5024f852e68
Autor:
Yunyun Wang, Sheng Liu, Lu Sun, Ning Xu, Shan Shan, Fei Wu, Xiaoping Liang, Yingzi Huang, Ed Luk, Carl Wu, Zheng Zhou
Publikováno v:
PLoS Biology, Vol 17, Iss 5, p e3000277 (2019)
Chz1 is a specific chaperone for the histone variant H2A.Z in budding yeast. The ternary complex formed by Chz1 and H2A.Z-H2B dimer is the major in vivo substrate of Swi2/snif2-related 1 (SWR1), the ATP-dependent chromatin remodeling enzyme that depo
Externí odkaz:
https://doaj.org/article/780f576cbb504151931557443b0a3d36
Autor:
Xiangyu Chen, Robert Gaglione, Trevor Leong, Lauren Bednor, Teresa de Los Santos, Ed Luk, Michael Airola, Nancy M Hollingsworth
Publikováno v:
PLoS Genetics, Vol 14, Iss 11, p e1007832 (2018)
Meiotic recombination plays a critical role in sexual reproduction by creating crossovers between homologous chromosomes. These crossovers, along with sister chromatid cohesion, connect homologs to enable proper segregation at Meiosis I. Recombinatio
Externí odkaz:
https://doaj.org/article/9e8b7323a63d4f008854ac9a5198d8a2
Autor:
Kayo Nozawa, Yoshimasa Takizawa, Leonidas Pierrakeas, Chizuru Sogawa-Fujiwara, Kazumi Saikusa, Satoko Akashi, Ed Luk, Hitoshi Kurumizaka
Publikováno v:
Proceedings of the National Academy of Sciences. 119
The canonical nucleosome, which represents the major packaging unit of eukaryotic chromatin, has an octameric core composed of two histone H2A-H2B and H3-H4 dimers with ∼147 base pairs (bp) of DNA wrapped around it. Non-nucleosomal particles with a
Publikováno v:
eLife, Vol 7 (2018)
VivosX is an in vivo disulfide crosslinking approach that utilizes a pair of strategically positioned cysteines on two proteins to probe physical interactions within cells. Histone H2A.Z, which often replaces one or both copies of H2A in nucleosomes
Externí odkaz:
https://doaj.org/article/4da963f5a6e34969a27dd97359defd4d
Autor:
Michael Tramantano, Lu Sun, Christy Au, Daniel Labuz, Zhimin Liu, Mindy Chou, Chen Shen, Ed Luk
Publikováno v:
eLife, Vol 5 (2016)
The assembly of the preinitiation complex (PIC) occurs upstream of the +1 nucleosome which, in yeast, obstructs the transcription start site and is frequently assembled with the histone variant H2A.Z. To understand the contribution of the transcripti
Externí odkaz:
https://doaj.org/article/f192fa339f2b4d3cbef3f2cce5cdc0c7
Publikováno v:
Proc Natl Acad Sci U S A
The SWR complex edits the histone composition of nucleosomes at promoters to facilitate transcription by replacing the two nucleosomal H2A-H2B (A-B) dimers with H2A.Z-H2B (Z-B) dimers. Swc5, a subunit of SWR, binds to A-B dimers, but its role in the
Publikováno v:
Cell Reports, Vol 30, Iss 1, Pp 257-268.e5 (2020)
Summary: In preparation for transcription, the chromatin remodeler SWR installs homotypic ZZ nucleosomes at promoters by replacing the two nucleosomal H2A with H2A.Z in a stepwise manner. Nucleosome-free regions (NFRs) help recruit SWR to promoters;
Autor:
Kayo Nozawa, Yoshimasa Takizawa, Leonidas Pierrakeas, Kazumi Saikusa, Satoko Akashi, Ed Luk, Hitoshi Kurumizaka
The canonical nucleosome, which represents the predominant packaging unit in eukaryotic chromatin, has an octameric core made up of two histone H2A-H2B and H3-H4 dimers with ~147 base-pair (bp) DNA wrapping around it. Non-nucleosome particles with al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c79fcad549aa584116279ae1b15dc351
https://doi.org/10.1101/2021.10.27.466091
https://doi.org/10.1101/2021.10.27.466091