Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Ed Lemmens"'
Autor:
Dirk G. Brockstedt, Thomas Müller, Chan Whiting, Aimee Murphy, Elizabeth M. Jaffee, Dung T. Le, Serena Chang, Ed Lemmens, Shih-Yu Chen, Nitya Nair
Cellular biomarkers are independent of treatment in the validation patient cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1bea0c40f1e5ccd8590683db394cbcb
https://doi.org/10.1158/2326-6066.22543290.v1
https://doi.org/10.1158/2326-6066.22543290.v1
Autor:
Dirk G. Brockstedt, Thomas Müller, Chan Whiting, Aimee Murphy, Elizabeth M. Jaffee, Dung T. Le, Serena Chang, Ed Lemmens, Shih-Yu Chen, Nitya Nair
Metal-tagged antibody panel used for mass cytometry analysis and fluorescence-tagged antibody panels used for flow cytometry analysis in training and verification sets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b3472caddc8f96af9b5895d6279459
https://doi.org/10.1158/2326-6066.22543284.v1
https://doi.org/10.1158/2326-6066.22543284.v1
Autor:
Dirk G. Brockstedt, Thomas Müller, Chan Whiting, Aimee Murphy, Elizabeth M. Jaffee, Dung T. Le, Serena Chang, Ed Lemmens, Shih-Yu Chen, Nitya Nair
The identification of biomarkers for patient stratification is fundamental to precision medicine efforts in oncology. Here, we identified two baseline, circulating immune cell subsets associated with overall survival in patients with metastatic pancr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0db0e4e1fbad3775dadc1d024cb6185a
https://doi.org/10.1158/2326-6066.c.6550203
https://doi.org/10.1158/2326-6066.c.6550203
Autor:
Dirk G. Brockstedt, Lisa M. Coussens, Elizabeth Jaffee, Aimee L. Murphy, Katherine McDougall, Anish Thomas, Gina Choe, Sushil Kumar, Takahiro Tsujikawa, Ed Lemmens, Amanda Enstrom, Chan C. Whiting, Nitya Nair, Somayeh Honarmand, Thierry Jahan, Scott Antonia, Hedy Kindler, Evan Alley, Raffit Hassan
Intratumoral leukocyte composition of mesothelioma representing pre- and post-therapy immunotherapy, evaluated by multiplex IHC.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::897eba123b3833f4c567c16bb2cda523
https://doi.org/10.1158/1078-0432.22474538.v1
https://doi.org/10.1158/1078-0432.22474538.v1
Autor:
Dirk G. Brockstedt, Lisa M. Coussens, Elizabeth Jaffee, Aimee L. Murphy, Katherine McDougall, Anish Thomas, Gina Choe, Sushil Kumar, Takahiro Tsujikawa, Ed Lemmens, Amanda Enstrom, Chan C. Whiting, Nitya Nair, Somayeh Honarmand, Thierry Jahan, Scott Antonia, Hedy Kindler, Evan Alley, Raffit Hassan
Purpose:Malignant pleural mesothelioma (MPM) is an aggressive cancer associated with poor prognosis. CRS-207 is a live-attenuated Listeria monocytogenes engineered to express mesothelin, a tumor-associated antigen highly expressed in MPM. CRS-207 ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41f2427151e4d7b71687742dd6f4d613
https://doi.org/10.1158/1078-0432.c.6528815.v1
https://doi.org/10.1158/1078-0432.c.6528815.v1
Autor:
Dirk G. Brockstedt, Lisa M. Coussens, Elizabeth Jaffee, Aimee L. Murphy, Katherine McDougall, Anish Thomas, Gina Choe, Sushil Kumar, Takahiro Tsujikawa, Ed Lemmens, Amanda Enstrom, Chan C. Whiting, Nitya Nair, Somayeh Honarmand, Thierry Jahan, Scott Antonia, Hedy Kindler, Evan Alley, Raffit Hassan
Biomarkers utilized for defining immune cell lineages in IHC analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92fc1f95240c5ea8af67e6f3dec8739a
https://doi.org/10.1158/1078-0432.22474529.v1
https://doi.org/10.1158/1078-0432.22474529.v1
Autor:
Chan C. Whiting, Nitya Nair, Aimee Murphy, Ed Lemmens, Elizabeth M. Jaffee, Serena Chang, Thomas Müller, Dirk G. Brockstedt, Shih-Yu Chen, Dung T. Le
Publikováno v:
Cancer Immunol Res
The identification of biomarkers for patient stratification is fundamental to precision medicine efforts in oncology. Here, we identified two baseline, circulating immune cell subsets associated with overall survival in patients with metastatic pancr
Autor:
Raffit, Hassan, Evan, Alley, Hedy, Kindler, Scott, Antonia, Thierry, Jahan, Somayeh, Honarmand, Nitya, Nair, Chan C, Whiting, Amanda, Enstrom, Ed, Lemmens, Takahiro, Tsujikawa, Sushil, Kumar, Gina, Choe, Anish, Thomas, Katherine, McDougall, Aimee L, Murphy, Elizabeth, Jaffee, Lisa M, Coussens, Dirk G, Brockstedt
Publikováno v:
Clin Cancer Res
PURPOSE: Malignant pleural mesothelioma (MPM) is an aggressive cancer associated with poor prognosis. CRS-207 is a live-attenuated Listeria monocytogenes engineered to express mesothelin, a tumor-associated antigen highly expressed in MPM. CRS-207 in
Autor:
Jennifer N. Uram, Andrea Wang-Gillam, Ed Lemmens, Dung T. Le, Justin Skoble, Deirdre Jill Cohen, Daniel A. Laheru, Beth Onners, Robert L. Fine, Todd S. Crocenzi, Michael A. Morse, John Grous, Tim F. Greten, Herbert J. Zeh, Thomas W. Dubensky, Dirk G. Brockstedt, Vincent J. Picozzi, Sara Solt, Gregory M. Springett, Aimee Murphy, Elizabeth M. Jaffee, Eric R. Lutz
Publikováno v:
Journal of Clinical Oncology. 33:1325-1333
Purpose GVAX pancreas, granulocyte-macrophage colony-stimulating factor–secreting allogeneic pancreatic tumor cells, induces T-cell immunity to cancer antigens, including mesothelin. GVAX is administered with low-dose cyclophosphamide (Cy) to inhib
Autor:
Robert S. Warren, Mary Matli, Chih Yang Wang, Robert A H Van De Ven, Ed Lemmens, David B. Donner, Zena Werb, Philippe Depeille, Kevin M. Haigis, Linda M. Henricks, Jeroen P. Roose
Publikováno v:
Nature cell biology, vol 17, iss 6
The character of EGFR signals can influence cell fate but mechanistic insights into intestinal EGFR-Ras signalling are limited. Here we show that two distinct Ras nucleotide exchange factors, RasGRP1 and SOS1, lie downstream of EGFR but act in functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57d4080a60519928185f0a1c0dfafc1d
https://escholarship.org/uc/item/7p34w5gv
https://escholarship.org/uc/item/7p34w5gv