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of 2
pro vyhledávání: '"Ed Driggers"'
Autor:
Shinsan M. Su, Shunqi Yan, Ed Driggers, Wentao Wei, Cheng Fang, Shengfang Jin, Jeff Hixon, Yi Gao, Giovanni Cianchetta, Francesco G. Salituro, Lewis C. Cantley, Kevin Qian, Fan Jiang, Sung Choe, Kaiko Kunii, Matthew G. Vander Heiden, Shalini Sethumadhavan, Erin Murphy, Katharine E. Yen, Stuart Murray, Hin Koon Woo, Charles Kung, Jeffrey O. Saunders, Shaohui Wang, Xiling Wang, Wei Liu, Lenny Dang, Kevin Marks, Byron DeLaBarre, Stefan Gross, Hua Yang
Publikováno v:
Chemistry & Biology. 19(9):1187-1198
SummaryProliferating tumor cells use aerobic glycolysis to support their high metabolic demands. Paradoxically, increased glycolysis is often accompanied by expression of the lower activity PKM2 isoform, effectively constraining lower glycolysis. Her
Autor:
Jeff Hixon, Shaohui Wang, Hin Koon Woo, Charles Kung, Francesco G. Salituro, Stefan Gross, Ed Driggers, Stuart Murray, Yi Gao, Hua Yang, Shengfang Jin, Fang Cheng, Katherine Yen, Jeffrey O. Saunders, Xiling Wang, Sung Choe, Michael Su, Lenny Dang, Kevin Marks
Publikováno v:
Cancer Research. 72:1002-1002
It is well recognized that proliferating tumor cells invariably utilize aerobic glycolysis to support their high metabolic demands. Recent studies have further elucidated the paradoxical observation that this increase in glycolysis in proliferating t