Zobrazeno 1 - 10
of 899
pro vyhledávání: '"Eckhard Wolf"'
Autor:
Sarah Grimus, Victoria Sarangova, Petra B. Welzel, Barbara Ludwig, Jochen Seissler, Elisabeth Kemter, Eckhard Wolf, Asghar Ali
Publikováno v:
Advanced Science, Vol 11, Iss 31, Pp n/a-n/a (2024)
Abstract Type 1 diabetes mellitus (T1DM) is characterized by absolute insulin deficiency primarily due to autoimmune destruction of pancreatic β‐cells. The prevailing treatment for T1DM involves daily subcutaneous insulin injections, but a substan
Externí odkaz:
https://doaj.org/article/81d8d2b5304a4da893a6f63d70c7a318
Autor:
Bachuki Shashikadze, Florian Flenkenthaler, Elisabeth Kemter, Sophie Franzmeier, Jan B. Stöckl, Mark Haid, Fabien Riols, Michael Rothe, Lisa Pichl, Simone Renner, Andreas Blutke, Eckhard Wolf, Thomas Fröhlich
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 7 (2024)
Externí odkaz:
https://doaj.org/article/3cb2b91669fa4ab2bc4c32cd55bff7dd
Autor:
Kazutoshi Okamoto, Hitomi Matsunari, Kazuaki Nakano, Kazuhiro Umeyama, Koki Hasegawa, Ayuko Uchikura, Shuko Takayanagi, Masahito Watanabe, Jun Ohgane, Michael Stirm, Mayuko Kurome, Nikolai Klymiuk, Masaki Nagaya, Eckhard Wolf, Hiroshi Nagashima
Publikováno v:
Regenerative Therapy, Vol 24, Iss , Pp 451-458 (2023)
Introduction: Duchenne muscular dystrophy (DMD) is a hereditary neuromuscular disorder caused by mutation in the dystrophin gene (DMD) on the X chromosome. Female DMD carriers occasionally exhibit symptoms such as muscle weakness and heart failure. H
Externí odkaz:
https://doaj.org/article/51df675076934a228d6302859f500d01
Autor:
Graf, Alexander, Hanns-Joachim, Rziha, Stefan, Krebs, Eckhard, Wolf, Helmut, Blum, Mathias, Büttner
Publikováno v:
In Virus Research August 2024 346
Autor:
Julia Bauer, Julia Vlcek, Valerie Pauly, Nora Hesse, Ruibing Xia, Li Mo, Aparna Sharma Chivukula, Hannes Villgrater, Marie Dressler, Bianca Hildebrand, Eckhard Wolf, Konstantinos D. Rizas, Axel Bauer, Stefan Kääb, Philipp Tomsits, Dominik Schüttler, Sebastian Clauss
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 9 (2024)
Background Periodic repolarization dynamics (PRD) is an electrocardiographic biomarker that captures repolarization instability in the low frequency spectrum and is believed to estimate the sympathetic effect on the ventricular myocardium. High PRD i
Externí odkaz:
https://doaj.org/article/ec48d6e8e9fe460fbf10c6b6402d7e9c
Autor:
Masahito Watanabe, Hitomaru Miyamoto, Kazutoshi Okamoto, Kazuaki Nakano, Hitomi Matsunari, Kanako Kazuki, Koki Hasegawa, Ayuko Uchikura, Shuko Takayanagi, Kazuhiro Umeyama, Yosuke Hiramuki, Elisabeth Kemter, Nikolai Klymuik, Mayuko Kurome, Barbara Kessler, Eckhard Wolf, Yasuhiro Kazuki, Hiroshi Nagashima
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 444-453 (2023)
Mammalian artificial chromosomes have enabled the introduction of extremely large amounts of genetic information into animal cells in an autonomously replicating, nonintegrating format. However, the evaluation of human artificial chromosomes (HACs) a
Externí odkaz:
https://doaj.org/article/7a8c635119da410397f678e585a6364e
Autor:
Martin Bender, Jan-Michael Abicht, Bruno Reichart, Elisabeth Neumann, Julia Radan, Maren Mokelke, Ines Buttgereit, Maria Leuschen, Felicia Wall, Sebastian Michel, Reinhard Ellgass, Stig Steen, Audrius Paskevicius, Andreas Lange, Barbara Kessler, Elisabeth Kemter, Nikolai Klymiuk, Joachim Denner, Antonia W. Godehardt, Ralf R. Tönjes, Jonathan M. Burgmann, Constança Figueiredo, Anastasia Milusev, Valentina Zollet, Neda Salimi-Afjani, Alain Despont, Robert Rieben, Stephan Ledderose, Christoph Walz, Christian Hagl, David Ayares, Eckhard Wolf, Michael Schmoeckel, Paolo Brenner, Uli Binder, Michaela Gebauer, Arne Skerra, Matthias Längin
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1927 (2024)
The blockade of the CD40/CD40L immune checkpoint is considered essential for cardiac xenotransplantation. However, it is still unclear which single antibody directed against CD40 or CD40L (CD154), or which combination of antibodies, is better at prev
Externí odkaz:
https://doaj.org/article/8c1badf713bc4998ad88ccdb88bead35
Autor:
Martin Bender, Jan-Michael Abicht, Bruno Reichart, Maria Leuschen, Felicia Wall, Julia Radan, Elisabeth Neumann, Maren Mokelke, Ines Buttgereit, Sebastian Michel, Reinhard Ellgass, Katja Gieseke, Stig Steen, Audrius Paskevicius, Joachim Denner, Antonia W. Godehardt, Ralf R. Tönjes, Christian Hagl, David Ayares, Eckhard Wolf, Michael Schmoeckel, Paolo Brenner, Martin B. Müller, Matthias Längin
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1336 (2024)
Cardiac xenotransplantation has seen remarkable success in recent years and is emerging as the most promising alternative to human cardiac allotransplantation. Despite these achievements, acute vascular rejection still presents a challenge for long-t
Externí odkaz:
https://doaj.org/article/c841e0d47f65460a97bd17080a2ace3d
Autor:
Bristy Sabikunnahar, Sydney Caldwell, Stella Varnum, Tyler Hogan, Karolyn G. Lahue, Birgit Rathkolb, Raffaele Gerlini, Nathalia R. V. Dragano, Antonio Aguilar‐Pimentel, Martin Irmler, Adrián Sanz‐Moreno, Patricia daSilva‐Buttkus, German Mouse Clinic Consortium, Johannes Beckers, Eckhard Wolf, Valerie Gailus‐Durner, Helmut Fuchs, Martin Hrabe de Angelis, Jennifer L. Ather, Matthew E. Poynter, Dimitry N. Krementsov
Publikováno v:
Physiological Reports, Vol 12, Iss 1, Pp n/a-n/a (2024)
Abstract Obesity is a global health problem characterized by excessive fat accumulation, driven by adipogenesis and lipid accumulation. Long non‐coding RNAs (lncRNAs) have recently been implicated in regulating adipogenesis and adipose tissue funct
Externí odkaz:
https://doaj.org/article/737caf1a9abf472aaf1a165f9f9cba24
Autor:
Bachuki Shashikadze, Libera Valla, Salvo Danilo Lombardo, Cornelia Prehn, Mark Haid, Fabien Riols, Jan Bernd Stöckl, Radwa Elkhateib, Simone Renner, Birgit Rathkolb, Jörg Menche, Martin Hrabĕ de Angelis, Eckhard Wolf, Elisabeth Kemter, Thomas Fröhlich
Publikováno v:
Molecular Metabolism, Vol 75, Iss , Pp 101768- (2023)
Objective: To gain mechanistic insights into adverse effects of maternal hyperglycemia on the liver of neonates, we performed a multi-omics analysis of liver tissue from piglets developed in genetically diabetic (mutant INS gene induced diabetes of y
Externí odkaz:
https://doaj.org/article/1a3ade5bcba844d0a7579bde026e355d