Potent and selective EGFR inhibitors based on 5-aryl-7H-pyrrolopyrimidin-4-amines

Autor: Reiersølmoen, Ann Christin, Aarhus, Thomas Ihle, Eckelt, Sarah, Nørsett, Kristin Gabestad, Sundby, Eirik, Hoff, Bård Helge

Externí odkaz: http://hdl.handle.net/11250/2635253

Potent and selective EGFR inhibitors based on 5-aryl-7H-pyrrolopyrimidin-4-amines.

Autor: Reiersølmoen AC; Department of Chemistry, Norwegian University of Science and Technology (NTNU), NO-7491 Trondheim, Norway. Electronic address: Ann.C.Reiersolmoen@ntnu.no., Aarhus TI; Department of Chemistry, Norwegian University of Science and Technology (NTNU), NO-7491 Trondheim, Norway; Department of Material Science, Norwegian University of Science and Technology (NTNU), NO-7491 Trondheim, Norway. Electronic address: Thomas.Aarhus@ntnu.no., Eckelt S; Department of Chemistry, Norwegian University of Science and Technology (NTNU), NO-7491 Trondheim, Norway; Institute of Organic Chemistry, Universität Hamburg, Welckerstrasse 8, 201354 Hamburg, Germany., Nørsett KG; Department of Biomedical Laboratory Science, Norwegian University of Science and Technology (NTNU), NO-7491 Trondheim, Norway; Department of Computer Science, Norwegian University of Science and Technology (NTNU), NO-7491 Trondheim, Norway. Electronic address: Kristin.Norsett@ntnu.no., Sundby E; Department of Material Science, Norwegian University of Science and Technology (NTNU), NO-7491 Trondheim, Norway. Electronic address: Eirik.Sundby@ntnu.no., Hoff BH; Department of Chemistry, Norwegian University of Science and Technology (NTNU), NO-7491 Trondheim, Norway. Electronic address: bard.helge.hoff@chem.ntnu.no.

Publikováno v: Bioorganic chemistry [Bioorg Chem] 2019 Jul; Vol. 88, pp. 102918. Date of Electronic Publication: 2019 Apr 11.