Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Eckart Bindewald"'
Autor:
Paul Zakrevsky, Eckart Bindewald, Hadley Humbertson, Mathias Viard, Nomongo Dorjsuren, Bruce A. Shapiro
Publikováno v:
Nanomaterials, Vol 9, Iss 4, p 615 (2019)
Several varieties of small nucleic acid constructs are able to modulate gene expression via one of a number of different pathways and mechanisms. These constructs can be synthesized, assembled and delivered to cells where they are able to impart regu
Externí odkaz:
https://doaj.org/article/8a91c0858f2144309317ac92a4a1f1cf
Publikováno v:
Molecules, Vol 23, Iss 12, p 3329 (2018)
Cells frequently simultaneously express RNAs and cognate antisense transcripts without necessarily leading to the formation of RNA duplexes. Here, we present a novel transcriptome-wide experimental approach to ascertain the presence of accessible dou
Externí odkaz:
https://doaj.org/article/251cc2fa734d493a9533e06254580acf
Autor:
Saleh Tamim, Dat T Vo, Philip J Uren, Mei Qiao, Eckart Bindewald, Wojciech K Kasprzak, Bruce A Shapiro, Helder I Nakaya, Suzanne C Burns, Patricia R Araujo, Ichiro Nakano, Agnes J Radek, Scott Kuersten, Andrew D Smith, Luiz O F Penalva
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85591 (2014)
miR-137 plays critical roles in the nervous system and tumor development; an increase in its expression is required for neuronal differentiation while its reduction is implicated in gliomagenesis. To evaluate the potential of miR-137 in glioblastoma
Externí odkaz:
https://doaj.org/article/07dfca16fddd4fbc9d890bfd951dd082
Autor:
Arti N. Santhanam, Eckart Bindewald, Vinagolu K. Rajasekhar, Ola Larsson, Nahum Sonenberg, Nancy H. Colburn, Bruce A. Shapiro
Publikováno v:
PLoS ONE, Vol 4, Iss 4 (2009)
Externí odkaz:
https://doaj.org/article/cd0bf0f150b14b1492877e1e1be28e01
Autor:
Arti N Santhanam, Eckart Bindewald, Vinagolu K Rajasekhar, Ola Larsson, Nahum Sonenberg, Nancy H Colburn, Bruce A Shapiro
Publikováno v:
PLoS ONE, Vol 4, Iss 3, p e4868 (2009)
Eukaryotic cap-dependent mRNA translation is mediated by the initiation factor eIF4E, which binds mRNAs and stimulates efficient translation initiation. eIF4E is often overexpressed in human cancers. To elucidate the molecular signature of eIF4E targ
Externí odkaz:
https://doaj.org/article/62e38b4c79bb44c0848a386f18814a93
Autor:
Eckart Bindewald, Bruce A. Shapiro
Publikováno v:
RNA Nanotechnology and Therapeutics ISBN: 9781003001560
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cafcb55ab7eae0c360787429f3cd629d
https://doi.org/10.1201/9781003001560-18
https://doi.org/10.1201/9781003001560-18
Publikováno v:
RNA Biology
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Secondary structure prediction approaches rely typically on models of equilibrium free energies that are themselves based on in vitro physical chemistry. Recent transcriptome-wide experiments of in vivo RNA structure based on SHAPE-MaP experiments pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb633f07eee68028284e8ba866cf17a
https://doi.org/10.1080/15476286.2020.1760534
https://doi.org/10.1080/15476286.2020.1760534
Autor:
William F. Heinz, Eric A. Fields, Eckart Bindewald, Nomongo Dorjsuren, Luc Jaeger, Bruce A. Shapiro, Htet Khant, Natalia de Val, Paul Zakrevsky, Wojciech Kasprzak, Weimin Wu
Publikováno v:
Nanoscale. 12:2555-2568
Using RNA as a material for nanoparticle construction provides control over particle size and shape at the nano-scale. RNA nano-architectures have shown promise as delivery vehicles for RNA interference (RNAi) substrates, allowing multiple functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5589eb241ac51e655ec27c93958311e0
https://doi.org/10.1039/c9nr08197f
https://doi.org/10.1039/c9nr08197f
Autor:
Bruce A. Shapiro, Kirill A. Afonin, Emily Satterwhite, Mathias Viard, Jaclyn Smollett, Wojciech Kasprzak, Eckart Bindewald, Justin R. Halman, Lorena Parlea, Paul Zakrevsky
Publikováno v:
RNA & disease (Houston, Tex.)
The targeted and conditional activation of pharmaceuticals is an increasingly important feature in modern personalized medicine. Nucleic acid nanoparticles show tremendous potential in this exploit due to their programmability and biocompatibility. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0beba55a5c0eab0393b66ce9cd939ff4
https://pubmed.ncbi.nlm.nih.gov/34307841
https://pubmed.ncbi.nlm.nih.gov/34307841
Autor:
Eckart Bindewald
Publikováno v:
Ecological Modelling. 362:69-79
Recently, a game-theoretic analysis highlighted the attractiveness of motivation asymmetry and anti-coordination as a strategy for groups to achieve multiple simultaneous goals. To test the prevalence of motivation asymmetry, a survey was performed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a3b850e86d75282341cac00f30ccdfd
https://doi.org/10.1016/j.ecolmodel.2017.08.012
https://doi.org/10.1016/j.ecolmodel.2017.08.012