Zobrazeno 1 - 10
of 437
pro vyhledávání: '"Eckart, Meese"'
Autor:
Maike Pohlers, Selina Gies, Tanja Taenzer, Russalina Stroeder, Laura Theobald, Nicole Ludwig, Yoo‐Jin Kim, Rainer Maria Bohle, Erich Franz Solomayer, Eckart Meese, Martin Hart, Barbara Walch‐Rückheim
Publikováno v:
Molecular Oncology, Vol 18, Iss 9, Pp 2157-2178 (2024)
During cervical carcinogenesis, T‐helper (Th)‐17 cells accumulate in the peripheral blood and tumor tissues of cancer patients. We previously demonstrated that Th17 cells are associated with therapy resistance as well as cervical cancer metastase
Externí odkaz:
https://doaj.org/article/f428a7b9ddb34a2188fd9525ee1f3e6c
Autor:
Annika Engel, Nicole Ludwig, Friederike Grandke, Viktoria Wagner, Fabian Kern, Tobias Fehlmann, Georges P. Schmartz, Ernesto Aparicio-Puerta, Dominic Henn, Barbara Walch-Rückheim, Matthias Hannig, Stefan Rupf, Eckart Meese, Matthias W. Laschke, Andreas Keller
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 31-44 (2024)
Non-thermal plasma, a partially ionized gas, holds significant potential for clinical applications, including wound-healing support, oral therapies, and anti-tumour treatments. While its applications showed promising outcomes, the underlying molecula
Externí odkaz:
https://doaj.org/article/0f8aeea9ae554d44837d51695cf68609
Autor:
Martin Hart, Fabian Kern, Claudia Fecher-Trost, Lena Krammes, Ernesto Aparicio, Annika Engel, Pascal Hirsch, Viktoria Wagner, Verena Keller, Georges Pierre Schmartz, Stefanie Rheinheimer, Caroline Diener, Ulrike Fischer, Jens Mayer, Markus R. Meyer, Veit Flockerzi, Andreas Keller, Eckart Meese
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 4, Pp 935-945 (2024)
Abstract The identification of targetomes remains a challenge given the pleiotropic effect of miRNAs, the limited effects of miRNAs on individual targets, and the sheer number of estimated miRNA–target gene interactions (MTIs), which is around 44,5
Externí odkaz:
https://doaj.org/article/3efe0c622e26455595bea061ca0cb9f0
Autor:
Patrick Orth, Phillip Rolf Stahl, Wolfgang Tränkenschuh, Daniel Baumhoer, Tim Kehl, Hans-Peter Lehnhof, Günther Schneider, Eckart Meese, Henning Madry, Ulrike Fischer
Publikováno v:
Bone Reports, Vol 21, Iss , Pp 101765- (2024)
Osteolyses are common findings in elderly patients and most frequently represent malignant or locally aggressive bone tumors, infection, inflammatory and endocrine disorders, histiocytoses, and rare diseases such as Gorham-Stout syndrome. We here rep
Externí odkaz:
https://doaj.org/article/abf73037286b4859bd6639d6fb757a81
Autor:
Masood Abu-Halima, Andreas Keller, Lea Simone Becker, Ulrike Fischer, Annika Engel, Nicole Ludwig, Fabian Kern, Trine B. Rounge, Hilde Langseth, Eckart Meese, Verena Keller
Publikováno v:
RNA Biology, Vol 20, Iss 1, Pp 1-9 (2023)
For cancers and other pathologies, early diagnosis remains the most promising path to survival. Profiling of longitudinal cohorts facilitates insights into trajectories of biomarkers. We measured microRNA expression in 240 serum samples from patients
Externí odkaz:
https://doaj.org/article/510e66b6eacd43e18bfd37cdb72d0f39
Autor:
Fabian Kern, Thomas Kuhn, Nicole Ludwig, Martin Simon, Laura Gröger, Natalie Fabis, Ernesto Aparicio-Puerta, Abdulrahman Salhab, Tobias Fehlmann, Oliver Hahn, Annika Engel, Viktoria Wagner, Marcus Koch, Katarzyna Winek, Hermona Soreq, Irina Nazarenko, Gregor Fuhrmann, Tony Wyss-Coray, Eckart Meese, Verena Keller, Matthias W. Laschke, Andreas Keller
Publikováno v:
RNA Biology, Vol 20, Iss 1, Pp 482-494 (2023)
Previous work on murine models and humans demonstrated global as well as tissue-specific molecular ageing trajectories of RNAs. Extracellular vesicles (EVs) are membrane vesicles mediating the horizontal transfer of genetic information between differ
Externí odkaz:
https://doaj.org/article/c4f989c3cc3d47828f08997c492f2092
Autor:
Martin Hart, Caroline Diener, Laetitia Lunkes, Stefanie Rheinheimer, Lena Krammes, Andreas Keller, Eckart Meese
Publikováno v:
Molecular Medicine, Vol 29, Iss 1, Pp 1-14 (2023)
Abstract Background Although a pivotal role of microRNA (miRNA, miR) in the pathogenesis of Huntington’s disease (HD) is increasingly recognized, the molecular functions of miRNAs in the pathomechanisms of HD await further elucidation. One of the m
Externí odkaz:
https://doaj.org/article/0578c66489664e6083912c40e38041c8
Autor:
Masood Abu-Halima, Lea Simone Becker, Mohammad A. Al Smadi, Lea Sophie Kunz, Laura Gröger, Eckart Meese
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Seminal plasma contains a variety of extracellular vesicles (EVs) that deliver RNAs including microRNAs (miRNAs) molecules. However, the roles of these EVs along with their delivered RNAs and their interactions with male infertility are not
Externí odkaz:
https://doaj.org/article/4f2549c30fad4a60a19f77a4754e1743
Autor:
Vivien Becker, Xu Yuan, Anne S. Boewe, Emmanuel Ampofo, Elke Ebert, Johannes Hohneck, Rainer M. Bohle, Eckart Meese, Yingjun Zhao, Michael D. Menger, Matthias W. Laschke, Yuan Gu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 421-436 (2023)
The tumor microenvironment stimulates the angiogenic activity of endothelial cells (ECs) to facilitate tumor vascularization, growth, and metastasis. The involvement of microRNA-186-5p (miR-186) in regulating the aberrant activity of tumor-associated
Externí odkaz:
https://doaj.org/article/cd58792a924c4f558ad1c42dfc301f1a
Autor:
Caroline Diener, Martin Hart, Claudia Fecher-Trost, Jessica Knittel, Stefanie Rheinheimer, Markus R. Meyer, Jens Mayer, Veit Flockerzi, Andreas Keller, Eckart Meese
Publikováno v:
Cellular & Molecular Biology Letters, Vol 28, Iss 1, Pp 1-16 (2023)
Abstract Among the concepts in biology that are widely taken granted is a potentiated cooperative effect of multiple miRNAs on the same target. This strong hypothesis contrasts insufficient experimental evidence. The quantity as well as the quality o
Externí odkaz:
https://doaj.org/article/6107573b558b458e821e4f0ddff8a018