Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ece Somuncular"'
Autor:
Tsu-Yi Su, Julia Hauenstein, Ece Somuncular, Özge Dumral, Elory Leonard, Charlotte Gustafsson, Efthymios Tzortzis, Aurora Forlani, Anne-Sofie Johansson, Hong Qian, Robert Månsson, Sidinh Luc
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Age is a risk factor for hematologic malignancies. Attributes of the aging hematopoietic system include increased myelopoiesis, impaired adaptive immunity, and a functional decline of the hematopoietic stem cells (HSCs) that maintain hematop
Externí odkaz:
https://doaj.org/article/ce8fe9bb60494b84ad3652fa933d6098
Autor:
Lucía Peña-Pérez, Shabnam Kharazi, Nicolai Frengen, Aleksandra Krstic, Thibault Bouderlique, Julia Hauenstein, Minghui He, Ece Somuncular, Xiaoze Li Wang, Carin Dahlberg, Charlotte Gustafsson, Ann-Sofie Johansson, Julian Walfridsson, Nadir Kadri, Petter Woll, Marcin Kierczak, Hong Qian, Lisa Westerberg, Sidinh Luc, Robert Månsson
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The development of B cells relies on an intricate network of transcription factors critical for developmental progression and lineage commitment. In the B cell developmental trajectory, a temporal switch from predominant Foxo3 to Foxo1 expression occ
Externí odkaz:
https://doaj.org/article/8607115034c64df893cbadd484c41780
Hematopoiesis is maintained by hematopoietic stem cells (HSCs) that replenish the blood lineages throughout life. It is well-established that the HSC pool is functionally heterogeneous consisting of cells differing in longevity, self-renewal ability,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ce11a104ac3a7aad64595b38af1c1a4
https://doi.org/10.1101/2023.03.20.533430
https://doi.org/10.1101/2023.03.20.533430
Autor:
Sidinh Luc, Jialiang Huang, Jennifer L. McEldoon, Ece Somuncular, Dan Li, Claire Rhodes, Shahan Mamoor, Serena Hou, Jian Xu, Stuart H. Orkin
Publikováno v:
Cell Reports, Vol 16, Iss 12, Pp 3181-3194 (2016)
B cell CLL/lymphoma 11A (BCL11A) is a transcription factor and regulator of hemoglobin switching that has emerged as a promising therapeutic target for sickle cell disease and thalassemia. In the hematopoietic system, BCL11A is required for B lymphop
Externí odkaz:
https://doaj.org/article/f4352ddea809447e87cd65eb97af8621
Autor:
Ece Somuncular, Julia Hauenstein, Prajakta Khalkar, Anne-Sofie Johansson, Özge Dumral, Nicolai S. Frengen, Charlotte Gustafsson, Giuseppe Mocci, Tsu-Yi Su, Hugo Brouwer, Christine L. Trautmann, Michael Vanlandewijck, Stuart H. Orkin, Robert Månsson, Sidinh Luc
Publikováno v:
Stem cell reports. 17(7)
Hematopoiesis is maintained by functionally diverse lineage-biased hematopoietic stem cells (HSCs). The functional significance of HSC heterogeneity and the regulatory mechanisms underlying lineage bias are not well understood. However, absolute puri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc910d1a5dca0a11b52eb767117edc34
https://pubmed.ncbi.nlm.nih.gov/35714596
https://pubmed.ncbi.nlm.nih.gov/35714596
Autor:
Ece Somuncular, Julia Hauenstein, Prajakta Khalkar, Özge Dumral, Anne-Sofie Johansson, Guiseppe Mocci, Charlotte Gustafsson, Nicolai Frengen, Tsu-Yi Su, Christine Trautmann, Hugo Brouwer, Michael Vanlandewijck, Stuart H. Orkin, Robert Månsson, Sidinh Luc
Publikováno v:
Experimental Hematology. 100:S103
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::392c6bb93682d80341aef5c20dd9784a
https://doi.org/10.1016/j.exphem.2021.12.343
https://doi.org/10.1016/j.exphem.2021.12.343
Autor:
Dan Li, Claire Rhodes, Shahan Mamoor, Jialiang Huang, Jian Xu, Stuart H. Orkin, Ece Somuncular, Sidinh Luc, Jennifer L. McEldoon, Serena Hou
Publikováno v:
Cell Reports, Vol 16, Iss 12, Pp 3181-3194 (2016)
SummaryB cell CLL/lymphoma 11A (BCL11A) is a transcription factor and regulator of hemoglobin switching that has emerged as a promising therapeutic target for sickle cell disease and thalassemia. In the hematopoietic system, BCL11A is required for B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b8c5856c574b589497721d05a1e083b
https://doi.org/10.1016/j.celrep.2016.08.064
https://doi.org/10.1016/j.celrep.2016.08.064
Autor:
Su, Tsu-Yi, Hauenstein, Julia, Somuncular, Ece, Dumral, Özge, Leonard, Elory, Gustafsson, Charlotte, Tzortzis, Efthymios, Forlani, Aurora, Johansson, Anne-Sofie, Qian, Hong, Månsson, Robert, Luc, Sidinh
Publikováno v:
Nature Communications; 9/11/2024, Vol. 15 Issue 1, p1-16, 16p
Autor:
Peña-Pérez, Lucía, Kharazi, Shabnam, Frengen, Nicolai, Krstic, Aleksandra, Bouderlique, Thibault, Hauenstein, Julia, He, Minghui, Somuncular, Ece, Li Wang, Xiaoze, Dahlberg, Carin, Gustafsson, Charlotte, Johansson, Ann-Sofie, Walfridsson, Julian, Kadri, Nadir, Woll, Petter, Kierczak, Marcin, Qian, Hong, Westerberg, Lisa, Luc, Sidinh, Månsson, Robert
Publikováno v:
Frontiers in Immunology; 5/4/2022, Vol. 13, p1-14, 14p