Immunohistochemistry on a panel of Emery-Dreifuss muscular dystrophy samples reveals nuclear envelope proteins as inconsistent markers for pathology

Autor: Le Thanh P, Meinke P, Korfali N, Srsen V, Michael Robson, Wehnert M, Schoser B, Ca, Sewry, Ec, Schirmer

Publikováno v: Europe PubMed Central
Thành, P L, Meinke, P, Korfali, N, Srsen, V, Robson, M, Wehnert, M, Schoser, B, Sewry, C & Schirmer, E 2017, ' Immunohistochemistry on a Panel of Emery-Dreifuss Muscular Dystrophy Samples Reveals Nuclear Envelope Proteins as Inconsistent Markers for Pathology ', Neuromuscular Disorders . https://doi.org/10.1016/j.nmd.2016.12.003
Neuromuscular Disorders

Highlights • Altered distribution of EDMD-linked proteins is not a general characteristic of EDMD. • Tissue-specific proteins exhibit altered distributions in some EDMD patients. • Variation in redistributed proteins in EDMD may underlie its cl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8338e090bcf917d289bd03f379b16b1b
http://europepmc.org/abstract/med/28214269

Reduction in Nuclear Size by DHRS7 in Prostate Cancer Cells and by Estradiol Propionate in DHRS7-Depleted Cells.

Autor: Rizzotto A; The Institute of Cell Biology, University of Edinburgh, Edinburgh EH9 3BF, UK., Tollis S; Institute of Biomedicine, University of Eastern Finland, 70210 Kuopio, Finland., Pham NT; The Institute of Quantitative Biology, Biochemistry and Biotechnology, University of Edinburgh, Edinburgh EH9 3BF, UK., Zheng Y; The Institute of Quantitative Biology, Biochemistry and Biotechnology, University of Edinburgh, Edinburgh EH9 3BF, UK., Abad MA; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh EH9 3BF, UK., Wildenhain J; The Institute of Quantitative Biology, Biochemistry and Biotechnology, University of Edinburgh, Edinburgh EH9 3BF, UK., Jeyaprakash AA; The Institute of Cell Biology, University of Edinburgh, Edinburgh EH9 3BF, UK.; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh EH9 3BF, UK.; Gene Center and Department of Biochemistry, LMU-München, 81377 Munich, Germany., Auer M; The Institute of Quantitative Biology, Biochemistry and Biotechnology, University of Edinburgh, Edinburgh EH9 3BF, UK.; Xenobe Research Institute, P.O. Box 3052, San Diego, CA 92163-1052, USA., Tyers M; Program in Molecular Medicine, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada., Schirmer EC; The Institute of Cell Biology, University of Edinburgh, Edinburgh EH9 3BF, UK.

Publikováno v: Cells [Cells] 2023 Dec 27; Vol. 13 (1). Date of Electronic Publication: 2023 Dec 27.

Editorial: Is aberrant genome organization a cause or consequence of specific diseases?

Autor: Schirmer EC; Institute of Cell Biology, University of Edinburgh, Edinburgh, United Kingdom., Bridger JM; Centre of Genome Engineering and Maintenance, Biosciences, Department of Life Sciences, College of Health, Medicine and Life Sciences, Brunel University London, Uxbridge, United Kingdom.

Publikováno v: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2023 Aug 29; Vol. 11, pp. 1271790. Date of Electronic Publication: 2023 Aug 29 (Print Publication: 2023).

Nuclear size rectification: A potential new therapeutic approach to reduce metastasis in cancer.

Autor: Schirmer EC; Institute of Cell Biology, University of Edinburgh, Edinburgh, United Kingdom., Latonen L; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.; Foundation for the Finnish Cancer Institute, Helsinki, Finland., Tollis S; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.

Publikováno v: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2022 Oct 10; Vol. 10, pp. 1022723. Date of Electronic Publication: 2022 Oct 10 (Print Publication: 2022).

Chemical Interrogation of Nuclear Size Identifies Compounds with Cancer Cell Line-Specific Effects on Migration and Invasion.

Autor: Tollis S; Institute of Biomedicine, University of Eastern Finland, Kuopio 70210, Finland.; Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Québec H3T 1J4, Canada., Rizzotto A; The Institute of Cell Biology, University of Edinburgh, Kings Buildings, Michael Swann Buildings, Max Born Crescent, Edinburgh EH9 3BF, U.K., Pham NT; Institute of Quantitative Biology, Biochemistry and Biotechnology, University of Edinburgh, Edinburgh EH9 3BF, U.K., Koivukoski S; Institute of Biomedicine, University of Eastern Finland, Kuopio 70210, Finland., Sivakumar A; The Institute of Cell Biology, University of Edinburgh, Kings Buildings, Michael Swann Buildings, Max Born Crescent, Edinburgh EH9 3BF, U.K., Shave S; Institute of Quantitative Biology, Biochemistry and Biotechnology, University of Edinburgh, Edinburgh EH9 3BF, U.K., Wildenhain J; Institute of Quantitative Biology, Biochemistry and Biotechnology, University of Edinburgh, Edinburgh EH9 3BF, U.K., Zuleger N; The Institute of Cell Biology, University of Edinburgh, Kings Buildings, Michael Swann Buildings, Max Born Crescent, Edinburgh EH9 3BF, U.K., Keys JT; Nancy E. and Peter C. Meinig School of Biomedical Engineering & Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York 14853, United States., Culley J; Edinburgh Cancer Research UK Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XR, U.K., Zheng Y; Institute of Quantitative Biology, Biochemistry and Biotechnology, University of Edinburgh, Edinburgh EH9 3BF, U.K., Lammerding J; Nancy E. and Peter C. Meinig School of Biomedical Engineering & Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York 14853, United States., Carragher NO; Edinburgh Cancer Research UK Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XR, U.K., Brunton VG; Edinburgh Cancer Research UK Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XR, U.K., Latonen L; Institute of Biomedicine, University of Eastern Finland, Kuopio 70210, Finland., Auer M; Institute of Quantitative Biology, Biochemistry and Biotechnology, University of Edinburgh, Edinburgh EH9 3BF, U.K., Tyers M; Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Québec H3T 1J4, Canada., Schirmer EC; The Institute of Cell Biology, University of Edinburgh, Kings Buildings, Michael Swann Buildings, Max Born Crescent, Edinburgh EH9 3BF, U.K.

Publikováno v: ACS chemical biology [ACS Chem Biol] 2022 Mar 18; Vol. 17 (3), pp. 680-700. Date of Electronic Publication: 2022 Feb 24.