Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Eby Sim"'
Autor:
Xiaomei Zhang, Elena Martinez, Connie Lam, Taryn Crighton, Eby Sim, Mailie Gall, Ellen J. Donnan, Ben J. Marais, Vitali Sintchenko
Publikováno v:
The Lancet Regional Health. Western Pacific, Vol 41, Iss , Pp 100910- (2023)
Summary: Background: Routine whole genome sequencing of Mycobacterium tuberculosis has been implemented with increasing frequency. However, its value for tuberculosis (TB) control programs beyond individual case management and enhanced drug resistanc
Externí odkaz:
https://doaj.org/article/3858c616a2494a66839dc6201252af6f
Autor:
Winkie Fong, Rebecca J. Rockett, Jessica E. Agius, Shona Chandra, Jessica Johnson-Mckinnon, Eby Sim, Connie Lam, Alicia Arnott, Mailie Gall, Jenny Draper, Susan Maddocks, Sharon Chen, Jen Kok, Dominic Dwyer, Matthew O’Sullivan, Vitali Sintchenko
Publikováno v:
BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-7 (2023)
Abstract The emergence of resistance to antiviral drugs increasingly used to treat SARS-CoV-2 infections has been recognised as a significant threat to COVID-19 control. In addition, some SARS-CoV-2 variants of concern appear to be intrinsically resi
Externí odkaz:
https://doaj.org/article/4fc407e2a2984577978554c2ee02e675
Autor:
Vitali Sintchenko, Verlaine Timms, Eby Sim, Rebecca Rockett, Nathan Bachmann, Matthew O'Sullivan, Ben Marais
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Virulence arresting drugs (VAD) are an expanding class of antimicrobial treatment that act to “disarm” rather than kill bacteria. Despite an increasing number of VAD being registered for clinical use, uptake is hampered by the lack of methods tha
Externí odkaz:
https://doaj.org/article/1894861c9fdb460ba099e12a086565e8
Publikováno v:
Journal of Antimicrobial Chemotherapy. 77:3016-3025
Background The emergence of macrolide resistance in Bordetella pertussis, the causative agent of pertussis, due to mutations in the 23S rRNA gene has been recently recognized. However, resistance mechanisms to macrolides in Bordetella parapertussis a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8088405016b8b86d72f2700774bb20cd
https://doi.org/10.1093/jac/dkac272
https://doi.org/10.1093/jac/dkac272
Autor:
Xiaomei Zhang, Connie Lam, Elena Martinez, Eby Sim, Taryn Crighton, Ben J Marais, Vitali Sintchenko
Minority variants ofMycobacterium tuberculosisharbouring mutations conferring resistance can become dominant populations during tuberculosis (TB) treatment, leading to treatment failure. Our understanding of drug resistant within-host sub-populations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2ccb830f01d60e3e8a33f10c7238cc4
https://doi.org/10.1101/2023.04.19.537555
https://doi.org/10.1101/2023.04.19.537555
Legionella pneumophila is ubiquitous and sporadically infects humans causing Legionnaires disease (LD). Globally, reported cases of LD has risen four-fold from 2000-2014. In 2016, Sydney, Australia was the epicentre of an outbreak caused by L. pneumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20b0d392fb0395950844ca3837a0ed93
https://doi.org/10.1101/2022.09.26.509626
https://doi.org/10.1101/2022.09.26.509626
Autor:
Eby Sim
Utilisation of long-read sequencing can reliably generate complete bacterial genomes. Here, we present a DNA extraction method which introduces minor modifications to the DNeasy® UltraClean® Microbial Kit (Qiagen) to generate DNA suitable for long-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e38f4142b54d46c9d89a22d7cf80247c
https://doi.org/10.17504/protocols.io.4r3l2ox24v1y/v1
https://doi.org/10.17504/protocols.io.4r3l2ox24v1y/v1
SABRes: A tool for in silico detection of drug resistance conferring mutations in SARS-CoV-2 genomes
Autor:
Winkie Fong, Rebecca Rockett, Jessica Agius, Jessica Johnson-Mackinnon, Shona Chandra, Eby Sim, Connie Lam, Alicia Arnott, Mailie Gall, Jenny Draper, Susan Maddocks, Sharon Chen, Jen Kok, Dominic Dwyer, Matthew O'Sullivan, Vitali Sintchenko
The emergence of resistance to antiviral drugs increasingly used to treat SARS-CoV-2 infections has been recognised as a significant threat to COVID-19 control. In addition, some SARS-CoV-2 variants of concern appear to be intrinsically resistant to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2875207a025fd8314a1e8c19d4462022
https://doi.org/10.21203/rs.3.rs-1683350/v1
https://doi.org/10.21203/rs.3.rs-1683350/v1
Autor:
Eby Sim, Nathan L. Bachmann, Rebecca J. Rockett, Ben J. Marais, Verlaine J. Timms, Vitali Sintchenko, Matthew V. N. O'Sullivan
Publikováno v:
Frontiers in Medicine
Frontiers in Medicine, Vol 8 (2021)
Frontiers in Medicine, Vol 8 (2021)
Virulence arresting drugs (VAD) are an expanding class of antimicrobial treatment that act to “disarm” rather than kill bacteria. Despite an increasing number of VAD being registered for clinical use, uptake is hampered by the lack of methods tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc8473ca90e086729d5595541195444
Autor:
Mikhail Prokopenko, Rosemarie Sadsad, Roy Byun, Jen Kok, Karen-Ann Gray, Vitali Sintchenko, Ian Carter, Dominic E. Dwyer, Sharon C.-A. Chen, Jenny Draper, Connie Lam, Eby Sim, Edward C. Holmes, Tania C. Sorrell, Matthew V O Sullivan, Rebecca J. Rockett, John-Sebastian Eden, Alicia Arnott, Kerri Basile, Sheryl L. Chang, Susan Maddocks, Verlaine J. Timms, Mailie Gall, Nathan L. Bachmann
Community transmission of the new coronavirus SARS-CoV-2 is a major public health concern that remains difficult to assess. We present a genomic survey of SARS-CoV-2 from a during the first 10 weeks of COVID-19 activity in New South Wales, Australia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67e176ba01ee8e1df319923e3d9d11fb
https://doi.org/10.1101/2020.04.19.048751
https://doi.org/10.1101/2020.04.19.048751