Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ebru Koçak Aslan"'
Autor:
Ebru Koçak Aslan, Muhammed İhsan Han, Vagolu Siva Krishna, Rasoul Tamhaev, Cagatay Dengiz, Şengül Dilem Doğan, Christian Lherbet, Lionel Mourey, Tone Tønjum, Miyase Gözde Gündüz
Publikováno v:
Pharmaceuticals, Vol 15, Iss 10, p 1301 (2022)
Isoniazid (INH) is one of the key molecules employed in the treatment of tuberculosis (TB), the most deadly infectious disease worldwide. However, the efficacy of this cornerstone drug has seriously decreased due to emerging INH-resistant strains of
Externí odkaz:
https://doaj.org/article/a33981310c2b4397b04312c17265e4aa
Publikováno v:
Turk J Pharm Sci
OBJECTIVES: Drug repurposing is a highly popular approach to find new indications for drugs, which greatly reduces time and costs for drug design and discovery. Non-selective inhibitors of histone deacetylase (HDAC) isoforms including sirtuins (SIRTs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ca6c1ffa03d5259cfcd6ba1795f839
https://europepmc.org/articles/PMC8744439/
https://europepmc.org/articles/PMC8744439/
Autor:
Suat, Sari, Suna, Sabuncuoğlu, Ebru, Koçak Aslan, Ahmet, Avci, Didem, Kart, Zeynep, Özdemir, M Fahir, Acar, Burcu, Sayoğlu, M Abdullah, Alagöz, Arzu, Karakurt, Sevim, Dalkara
Publikováno v:
Journal of biomolecular structuredynamics. 40(20)
Azoles are first-line drugs used in fungal infections. Topical antifungals, such as miconazole and econazole, are known to be active against Gram-positive bacteria, which was reported to result from bacterial flavohemoglobin (flavoHb) inhibition. Dua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8bd17a6af9820602c0fd8c82eb9a1835
https://pubmed.ncbi.nlm.nih.gov/34139139
https://pubmed.ncbi.nlm.nih.gov/34139139
Autor:
Ebru Koçak Aslan, Vagolu Siva Krishna, Sanja J. Armaković, Stevan Armaković, Onur Şahin, Tone Tønjum, Miyase Gözde Gündüz
Publikováno v:
Journal of Molecular Liquids. 354:118873
The current emergence of drug-resistant and multidrug-resistant (MDR) Mycobacterium tuberculosis (Mtb) strains has complicated and hampered attempts to eliminate or considerably reduce the global prevalence of the often life-threatening disease tuber
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0943b5978f1c5f7c7f1f8cbb2b8640ec
https://doi.org/10.1016/j.molliq.2022.118873
https://doi.org/10.1016/j.molliq.2022.118873
Autor:
Ebru Koçak Aslan, Sanja Skaro Bogojevic, Jasmina Nikodinovic-Runic, Miyase Gözde Gündüz, Cagatay Dengiz
Publikováno v:
Journal of Molecular Structure. 1247:131316
In the present study, we designed three novel compounds via the combination of two precious nitrogen-containing scaffolds; 1,4-dihydropyridine (DHP) and azole, in the same molecule. To synthesize the title compounds, initially, azolyl benzaldehydes w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96af48595e1b2e0a5bc89cb58d5c59cf
https://doi.org/10.1016/j.molstruc.2021.131316
https://doi.org/10.1016/j.molstruc.2021.131316