Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ebru Bilget Guven"'
Autor:
Deniz Cansen Kahraman, Ebru Bilget Guven, Peri S. Aytac, Gamze Aykut, Birsen Tozkoparan, Rengul Cetin Atalay
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Hepatocellular carcinoma (HCC) is a highly heterogeneous cancer, and resistant to both conventional and targeted chemotherapy. Recently, nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to decrease the incidence and mortality of
Externí odkaz:
https://doaj.org/article/de9102c153df4f01a413d6729442aabf
Publikováno v:
Acta Chimica Slovenica, Vol 67, Iss 1, Pp 70-82 (2020)
A series of new 6,9-disubstituted purine analogs with 4-substituted piperazine at C-6 and 4-substituted benzyl at N-9 were designed and synthesized in four steps. All synthesized compounds (7–26) were screened initially for their in vitro anticance
Externí odkaz:
https://doaj.org/article/1d0121fd63c6498eae381fa41e8547f4
Publikováno v:
Acta Chimica Slovenica, Vol 64, Iss 3, Pp 621-632 (2017)
A series of 6-(4-substituted phenyl)-9-(tetrahydropyran-2-yl)purines 3–9, 6-(4-substituted phenyl)purines 10–16, 9-((4-substituted phenyl)sulfonyl)-6-(4-substituted phenyl)purines 17–32 were prepared and screened initially for their in vitro an
Externí odkaz:
https://doaj.org/article/b51e5510129644baa97c0a1714b060aa
Autor:
Deniz Cansen Kahraman, Ebru Bilget Guven, Peri S. Aytac, Gamze Aykut, Birsen Tozkoparan, Rengul Cetin Atalay
Hepatocellular carcinoma (HCC) is a highly heterogeneous cancer, and resistant to both conventional and targeted chemotherapy. (NSAIDs) Recently, nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to decrease the incidence and mortality of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3c57a6f7d08b57c4d8523b389bbb2a4
https://doi.org/10.21203/rs.3.rs-1025268/v1
https://doi.org/10.21203/rs.3.rs-1025268/v1
Autor:
Zeynep Demir, Meral Tuncbilek, Rengul Cetin Atalay, Ebru Bilget Guven, Canan Kazak, Süheyla Özbey
Publikováno v:
European Journal of Medicinal Chemistry
Kazak, Canan/0000-0003-2475-8775; Guven, Ebru Bilget/0000-0001-9734-9679; Cetin-Atalay, Rengul/0000-0003-2408-6606 WOS: 000348003500058 PubMed: 25462277 Novel 9-(substituted amino/piperazinoethyl)adenines (4-12), 6-(substituted piperazino/amino)purin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dfb6c873d9d35f0900ce31b294b4c67
https://doi.org/10.1016/j.ejmech.2014.10.080
https://doi.org/10.1016/j.ejmech.2014.10.080
Autor:
Duygu Altiparmak, Ebru Bilget Guven, Meral Tuncbilek, Rengul Cetin-Atalay, Asligul Kucukdumlu
Publikováno v:
Bioorganic and Medicinal Chemistry Letters
New nucleoside derivatives with nitrogen substitution at the C-6 position were prepared and screened initially for their in vitro anticancer bioactivity against human epithelial cancer cells (liver Huh7, colon HCT116, breast MCF7) by the NCI-sulforho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ffe596fa66a16f4357ad13abaab7351
https://pubmed.ncbi.nlm.nih.gov/29326016
https://pubmed.ncbi.nlm.nih.gov/29326016
Publikováno v:
Acta Chimica Slovenica
Acta Chimica Slovenica, Vol 64, Iss 3, Pp 621-632 (2017)
Acta Chimica Slovenica, Vol 64, Iss 3, Pp 621-632 (2017)
A series of 6-(4-substituted phenyl)-9-(tetrahydropyran-2-yl)purines 3 – 9 , 6-(4-substituted phenyl)purines 10 – 16 , 9-((4-substituted phenyl)sulfonyl)-6-(4-substituted phenyl)purines 17 – 32 were prepared and screened initially for their in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1b2a9bf0f1dfbf4c95240857cbe3842
https://hdl.handle.net/11693/37007
https://hdl.handle.net/11693/37007
Liver cancer cells are sensitive to Lanatoside C induced cell death independent of their PTEN status
Autor:
Mehmet Ozturk, Ihsan Calis, Tulin Ersahin, Ebru Bilget Guven, Rengul Cetin-Atalay, Irem Durmaz
Publikováno v:
Phytomedicine
Background Hepatocellular carcinoma is the second deadliest cancer with limited treatment options. Loss of PTEN causes the P13K/Akt pathway to be hyperactive which contributes to cell survival and resistance to therapeutics in various cancers, includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::362b8e811eef14ad8191e0a1fec81f08
https://hdl.handle.net/11693/22147
https://hdl.handle.net/11693/22147
Publikováno v:
Journal of Medicinal Chemistry
Novel purine ribonucleoside analogues (9-13) containing a 4-substituted piperazine in the substituent at N 6 were synthesized and evaluated for their cytotoxicity on Huh7, HepG2, FOCUS, Mahlavu liver, MCF7 breast, and HCT116 colon carcinoma cell line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b467aec04ea2255d2052b2b228b0114e
https://hdl.handle.net/11693/21506
https://hdl.handle.net/11693/21506
Autor:
Emre Ozan Polat, M. Mustafa Cetin, Ahmet Fatih Tabak, Ebru Bilget Güven, Bengü Özuğur Uysal, Taner Arsan, Anas Kabbani, Houmeme Hamed, Sümeyye Berfin Gül
Publikováno v:
Biosensors, Vol 12, Iss 6, p 385 (2022)
The development of new biosensor technologies and their active use as wearable devices have offered mobility and flexibility to conventional western medicine and personal fitness tracking. In the development of biosensors, transducers stand out as th
Externí odkaz:
https://doaj.org/article/79090ae84da34483ba4c55faaaa0460e