Zobrazeno 1 - 10
of 381
pro vyhledávání: '"Ebneth A"'
Publikováno v:
Stem Cell Research, Vol 77, Iss , Pp 103414- (2024)
Late-onset Alzheimer’s disease (AD) has become the paradigm of a non-mendelian complex neurodegenerative disease, for which a major genetic determinant is known, the APOE locus. A rare APOE variant named Christchurch (APOEch) yielding a missense mu
Externí odkaz:
https://doaj.org/article/9dee6022aa0748dea0f8d1731bb99c91
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Kwok, Chee Keong, Sébastien, Isabelle, Hariharan, Krithika, Meiser, Ina, Wihan, Jeanette, Altmaier, Saskia, Karnatz, Isabell, Bauer, Dominic, Fischer, Benjamin, Feile, Alexander, Cabrera-Socorro, Alfredo, Rasmussen, Mikkel, Holst, Bjørn, Neubauer, Julia C., Clausen, Christian, Verfaillie, Catherine, Ebneth, Andreas, Hansson, Mattias, Steeg, Rachel, Zimmermann, Heiko
Publikováno v:
In Reproductive Toxicology September 2022 112:23-35
Autor:
Frank Herrmann, Manuela Hessmann, Sabine Schaertl, Karola Berg-Rosseburg, Christopher J Brown, Galina Bursow, Anass Chiki, Andreas Ebneth, Miriam Gehrmann, Nicole Hoeschen, Madlen Hotze, Stefanie Jahn, Peter D Johnson, Vinod Khetarpal, Alex Kiselyov, Karsten Kottig, Stefanie Ladewig, Hilal Lashuel, Sven Letschert, Matthew R Mills, Kathrin Petersen, Michael E Prime, Christoph Scheich, Gerhard Schmiedel, John Wityak, Longbin Liu, Celia Dominguez, Ignacio Muñoz-Sanjuán, Jonathan A Bard
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Huntington’s disease (HD) is caused by a CAG trinucleotide repeat expansion in the first exon of the huntingtin (HTT) gene coding for the huntingtin (HTT) protein. The misfolding and consequential aggregation of CAG-expanded mutant HTT (mH
Externí odkaz:
https://doaj.org/article/9ab72a1e5e324d34b23c0110b93bbd78
Publikováno v:
In Stem Cell Research December 2020 49
Publikováno v:
In Stem Cell Research December 2019 41
Autor:
Miles, Luke A., Hermans, Stefan J., Crespi, Gabriela A.N., Gooi, Jonathan H., Doughty, Larissa, Nero, Tracy L., Markulić, Jasmina, Ebneth, Andreas, Wroblowski, Berthold, Oehlrich, Daniel, Trabanco, Andrés A., Rives, Marie-Laure, Royaux, Ines, Hancock, Nancy C., Parker, Michael W.
Publikováno v:
In iScience 27 September 2019 19:110-118
Autor:
Pei-Yu Shih, Mohamed Kreir, Devesh Kumar, Frederik Seibt, Francisco Pestana, Benjamin Schmid, Bjørn Holst, Christian Clausen, Rachel Steeg, Benjamin Fischer, Juan Pita-Almenar, Andreas Ebneth, Alfredo Cabrera-Socorro
Publikováno v:
Stem Cell Research, Vol 54, Iss , Pp 102386- (2021)
Neurogenin 2 encodes a neural-specific transcription factor (NGN2) able to drive neuronal fate on somatic and stem cells. NGN2 is expressed in neural progenitors within the developing central and peripheral nervous systems. Overexpression of NGN2 in
Externí odkaz:
https://doaj.org/article/129b4bdeaf6047df924991f36d253277
Autor:
Luke A. Miles, Stefan J. Hermans, Gabriela A.N. Crespi, Jonathan H. Gooi, Larissa Doughty, Tracy L. Nero, Jasmina Markulić, Andreas Ebneth, Berthold Wroblowski, Daniel Oehlrich, Andrés A. Trabanco, Marie-Laure Rives, Ines Royaux, Nancy C. Hancock, Michael W. Parker
Publikováno v:
iScience, Vol 19, Iss , Pp 110-118 (2019)
Summary: Polymorphism in the microglial receptor CD33 gene has been linked to late-onset Alzheimer disease (AD), and reduced expression of the CD33 sialic acid-binding domain confers protection. Thus, CD33 inhibition might be an effective therapy aga
Externí odkaz:
https://doaj.org/article/22f8a82eaea94df5bb89f782ed04cc2d
Autor:
Sebastiaan Bijttebier, Dina Rodrigues Martins, Liesbeth Mertens, Karolien Grauwen, Wouter Bruinzeel, Roland Willems, José Manuel Bartolomé-Nebreda, Clara Theunis, Alexis Bretteville, Andreas Ebneth, Lieve Dillen
Publikováno v:
Journal of Proteome Research. 22:1309-1321