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Molecular mechanisms of MrgprA3-independent activation of the transient receptor potential ion channels TRPA1 and TRPV1 by chloroquine.

Autor: Fricke TC; Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, Hanover, Germany., Pantke S; Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, Hanover, Germany., Lüttmann B; Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, Hanover, Germany., Echtermeyer FG; Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, Hanover, Germany., Herzog C; Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, Hanover, Germany., Eberhardt MJ; Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, Hanover, Germany., Leffler A; Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, Hanover, Germany.

Publikováno v: British journal of pharmacology [Br J Pharmacol] 2023 Sep; Vol. 180 (17), pp. 2214-2229. Date of Electronic Publication: 2023 Apr 25.

Distinct Mechanisms Account for In Vitro Activation and Sensitization of TRPV1 by the Porphyrin Hemin.

Autor: Palmaers NE; Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, 30625 Hannover, Germany., Wiegand SB; Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, 30625 Hannover, Germany., Herzog C; Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, 30625 Hannover, Germany., Echtermeyer FG; Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, 30625 Hannover, Germany., Eberhardt MJ; Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, 30625 Hannover, Germany., Leffler A; Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, 30625 Hannover, Germany.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2021 Oct 08; Vol. 22 (19). Date of Electronic Publication: 2021 Oct 08.

Oxidation of methionine residues activates the high-threshold heat-sensitive ion channel TRPV2.

Autor: Fricke TC; Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, 30625 Hannover, Germany., Echtermeyer F; Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, 30625 Hannover, Germany., Zielke J; Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, 30625 Hannover, Germany., de la Roche J; Institute for Neurophysiology, Hannover Medical School, 30625 Hannover, Germany., Filipovic MR; Institut de Biochimie et Génétique Cellulaires, Université de Bordeaux, UMR 5095, F-33077 Bordeaux, France.; CNRS, Institut de Biochimie et Génétique Cellulaires, Université de Bordeaux, UMR 5095, F-33077 Bordeaux, France., Claverol S; Plateforme Protéome Centre Genomique Fonctionnelle Bordeaux, Université de Bordeaux, 33076 Bordeaux Cedex, France., Herzog C; Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, 30625 Hannover, Germany., Tominaga M; Division of Cell Signaling, Okazaki Institute for Integrative Bioscience, National Institute of Natural Sciences, 444-8787 Okazaki, Japan., Pumroy RA; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104., Moiseenkova-Bell VY; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104., Zygmunt PM; Department of Clinical Sciences Malmö, Lund University, SE-205 02 Malmö, Sweden., Leffler A; Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, 30625 Hannover, Germany; leffler.andreas@mh-hannover.de., Eberhardt MJ; Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, 30625 Hannover, Germany.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Nov 26; Vol. 116 (48), pp. 24359-24365. Date of Electronic Publication: 2019 Nov 12.

Differential cytotoxicity and intracellular calcium-signalling following activation of the calcium-permeable ion channels TRPV1 and TRPA1.

Autor: Stueber T; Department of Anaesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany., Eberhardt MJ; Department of Anaesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany., Caspi Y; Department of Medical Neurobiology, Institute for Medical Research Israel-Canada, The Hebrew University Faculty of Medicine, Israel; The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University, Jerusalem, Israel., Lev S; Department of Medical Neurobiology, Institute for Medical Research Israel-Canada, The Hebrew University Faculty of Medicine, Israel; The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University, Jerusalem, Israel., Binshtok A; Department of Medical Neurobiology, Institute for Medical Research Israel-Canada, The Hebrew University Faculty of Medicine, Israel; The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University, Jerusalem, Israel., Leffler A; Department of Anaesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany. Electronic address: leffler.andreas@mh-hannover.de.

Publikováno v: Cell calcium [Cell Calcium] 2017 Dec; Vol. 68, pp. 34-44. Date of Electronic Publication: 2017 Oct 18.