Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Eberhard Morgenstern"'
Autor:
Claudia Götz, Olivia Barton, Mathias Montenarh, Eberhard Morgenstern, Corinna Busch, Andreas Noll, Jürgen Günther
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 39:1707-1713
cdc25C is a phosphatase which regulates the activity of the mitosis promoting factor cyclin B/cdk1 by dephosphorylation, thus triggering G(2)/M transition. The activity and the sub-cellular localisation of cdc25C are regulated by phosphorylation. It
Publikováno v:
Annals of the New York Academy of Sciences. 936:449-455
The constitution of platelet-fibrin(ogen) contacts, the separation of the platelets initially aggregated, and the rearrangement of the platelet cytoskeleton during clot formation (0.5 to 60 minutes after thrombin stimulation) were investigated using
Autor:
Thomas Engel, Stephan Rust, Grazyna Herminghaus, Jerzy-Roch Nofer, Udo Seedorf, Horst Bluethmann, Martin Brodde, Gerd Assmann, Eberhard Morgenstern, Beate E. Kehrel
Publikováno v:
Journal of Biological Chemistry. 279:34032-34037
ATP binding cassette transporter A1 (ABCA1) is involved in regulation of intracellular lipid trafficking and export of cholesterol from cells to high density lipoproteins. ABCA1 defects cause Tangier disease, a disorder characterized by absence of hi
Autor:
Georg Peters, Nicola Spehr, Hugo Van Aken, Beate E. Kehrel, Silke Niemann, Eberhard Morgenstern, Mathias Herrmann
Publikováno v:
Circulation. 110:193-200
Background— Infective endocarditis (IE) caused by Staphylococcus aureus is associated with significant morbidity and mortality rates. Platelets play a dual role as adhesive cells forming associates with bacteria as well as specialized inflammatory
Autor:
Bernd Engelmann, Anita Eckly, Eberhard Morgenstern, Michael Spannagl, Antje Klocke, Christian Gachet, Christine Moosbauer, Meike Alex, Catherine Léon
Publikováno v:
Blood. 103:594-600
While the adenosine 5′-diphosphate (ADP) pathway is known to enhance thrombus formation by recruiting platelets and leukocytes to the primary layer of collagen-adhering platelets, its role for the initiation of coagulation has not been revealed. Ex
Autor:
Ingrid Müller, Matthias Kotzsch, Bernd Engelmann, Susanne Zieseniss, Meike Alex, Antje Klocke, Eberhard Morgenstern, Thomas Luther, Stefan Zahler, Klaus T. Preissner
Publikováno v:
The FASEB Journal. 17:1-20
Although tissue factor (TF), the principial initiator of physiological coagulation and pathological thrombosis, has recently been proposed to be present in human blood, the functional significance and location of the intravascular TF is unknown. In t
Autor:
Matthias Germer, Karl-Dieter Wohn, Barbara Yutzy, Eberhard Morgenstern, Klaus T. Preissner, Thomas Schmidt, S.M. Kanse
Publikováno v:
British Journal of Haematology. 104:901-908
In the present study the ability of plasminogen activator inhibitor type-1 (PAI-1) to interfere with platelet and megakaryoblastic cell adhesion was investigated. Both cell types exhibited integrin-dependent adhesion in a static system, mediated by
Autor:
Andreas Ruf, Eberhard Morgenstern
Publikováno v:
Seminars in Thrombosis and Hemostasis. 21:119-122
Platelet adhesion to ligands within the subendothelium induces platelet activation. Ultrastructural and immunocytochemical investigations were carried out to obtain information on the microtopography of the adhesive interactions. Rabbit platelets whi
Publikováno v:
Pediatric Hematology and Oncology. 18:355-357
Publikováno v:
Thrombosis and Haemostasis. 67:121-125
SummaryThe redistribution of the antibody-glycoprotein (GP) IIb/IIIa complex was investigated with the immuno-gold labeling technique in order to trace its transport in resting platelets. Washed platelets were incubated in the presence of aspirin and