Experiments for the detection of microbial biosignatures in ice grains from Europa and Enceladus

Autor: Nozair Khawaja, Fabian Klenner, Jonathan Hillier, Karen Olsson-Francis, Maryse Napoleoni, Miriam Pavlista, Eberhard Klauck, Frank Postberg, Bernd Abel, Janine Bönigk, Marie Dannenmann

Detecting and identifying biosignatures is key to the search for life on extraterrestrial ocean worlds. Saturn’s moon Enceladus emits a plume of gas and water ice grains, formed from its subsurface ocean, into space. A similar phenomenon is suspect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::959b53523c8dca903f8729e846c87784
https://doi.org/10.5194/egusphere-egu21-15475

Large scale ratcheting in a bacterial DEAH RHA type RNA helicase that modulates antibiotics susceptibility

Autor: Henning Urlaub, Bernhard Loll, Markus C. Wahl, Iwan Parfentev, Eberhard Klauck, J. Wollenhaupt, Lena M Grass, T. Barthel, Haike Antelmann

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the USA

Significance Bacteria rely on RNA-binding and RNA-remodeling proteins to regulate gene expression posttranscriptionally. RNA-dependent nucleoside-triphosphatases of the DEAH/RHA family constitute important posttranscriptional gene regulatory proteins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41287628fe8a580befe1e3ca50a58fe8
http://www.helmholtz-berlin.de/pubbin/oai_publication?VT=1&ID=105171

Region 2.1 of the Escherichia coli heat-shock sigma factor RpoH (σ 32) is necessary but not sufficient for degradation by the FtsH protease

Autor: Regine Hengge, Markus Obrist, Eberhard Klauck, Franz Narberhaus, Sonja Milek

Publikováno v: Microbiology. 153:2560-2571

The cellular level of the Escherichia coli heat-shock sigma factor RpoH (sigma32) is negatively controlled by chaperone-mediated proteolysis through the essential metalloprotease FtsH. Point mutations in the highly conserved region 2.1 stabilize RpoH

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d629a2c502bc20f050b7411ac3bcea8a
https://doi.org/10.1099/mic.0.2007/007047-0

The response regulator RssB, a recognition factor for σS proteolysis in Escherichia coli, can act like an anti-σS factor

Autor: Eberhard Klauck, Regine Hengge-Aronis, Gisela Becker

Publikováno v: Molecular Microbiology. 35:657-666

sigmaS (RpoS) is the master regulator of the general stress response in Escherichia coli. Several stresses increase cellular sigmaS levels by inhibiting proteolysis of sigmaS, which under non-stress conditions is a highly unstable protein. For this C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a21fcd5143bcd1f6e8732f25fd618270
https://doi.org/10.1046/j.1365-2958.2000.01736.x

Regulation of RssB-dependent proteolysis inEscherichia coli: a role for acetyl phosphate in a response regulator-controlled process

Autor: Daniela Fischer, Regine Hengge-Aronis, Magnus Lucassen, Kirsten Jung, Eberhard Klauck, Sandrine Bouché

Publikováno v: Molecular Microbiology. 27:787-795

Sigma(S) (RpoS) is a highly unstable global regulatory protein in Escherichia coli, whose degradation is inhibited by various stress signals, such as carbon starvation, high osmolarity and heat shock. As a consequence, these stresses result in the in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cac19877668117b8e9a431246e8b1866
https://doi.org/10.1046/j.1365-2958.1998.00725.x