Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Eberhard Jähnchen"'
Publikováno v:
European Journal of Clinical Pharmacology. 38:S53-S59
Healthy male volunteers received three different dose regimens of a controlled-release form of isosorbide-5-mononitrate (IS-5-MN; 60 mg per tablet). Dose regimen I consisted of a single daily dose of 60 mg given for 5 days. Dose regimen 11 was starte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b585aa28c8448481e7f2a515efa84fa1
https://doi.org/10.1007/bf01417565
https://doi.org/10.1007/bf01417565
Publikováno v:
European Journal of Clinical Pharmacology. 41
The haemodynamic effects and plasma concentrations of glyceryl trinitrate (GTN) and its dinitrate metabolites were investigated in 8 healthy male volunteers during 5 days of application of a new transdermal delivery system (TDS) with time-dependent r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6beb990cae664b70a48685182b333a6
https://doi.org/10.1007/bf00265902
https://doi.org/10.1007/bf00265902
Publikováno v:
Die Haut als Transportorgan für Arzneistoffe ISBN: 9783642724534
Die Anwendung Transdermaler Therapeutischer Systeme (TTS) mit konstanter Nitro-glycerinfreisetzung fuhrt zu einer Wirkungsabschwachung bzw. Wirkungsverlust nach kurzer Applikationsdauer. Mit einem neuen transdermalen System soll eine zeitabhangige Fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87029fb1334c458bc97f4f601915b87e
https://doi.org/10.1007/978-3-642-72452-7_10
https://doi.org/10.1007/978-3-642-72452-7_10
Publikováno v:
Journal of Pharmacy and Pharmacology. 40:403-407
The pharmacokinetics and the pharmacological response to phenprocoumon have been studied in female and male inbred Lewis-Wistar rats. A significantly lower clearance was found in female than in male rats (7.9 ± 1.4 vs 24.5 ± 2.5 mL h−1 kg−1, re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9004606b01f020b33fefc372f0e254d
https://doi.org/10.1111/j.2042-7158.1988.tb06304.x
https://doi.org/10.1111/j.2042-7158.1988.tb06304.x
Publikováno v:
European Journal of Clinical Pharmacology. 18:461-465
The cardiovascular effects of a single i.v. dose (2 mg/kg over 5 min) of lorcainide were studied in 14 patients with heart disease. In the haemodynamic part of the study (6 patients), the aortic and pulmonary systolic, diastolic and mean pressures, l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f43bcf5f3b905205c0ca83f9e2908d8
https://doi.org/10.1007/bf00874656
https://doi.org/10.1007/bf00874656
Publikováno v:
Clinical Pharmacology & Therapeutics. 21:731-735
The effect of cholestyramine (12 gm/day divided into 3 doses) on the pharmacokinetics and pharmacodynamics of a single intravenouse dose (30 mg) of phenprocoumon was studied in 6 normal subjects. Cholestyramine treatment led to an increase in the rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1535b5fb7d15d2f3509592fe9b7acf91
https://doi.org/10.1002/cpt1977216731
https://doi.org/10.1002/cpt1977216731
Publikováno v:
Comparative Biochemistry and Physiology Part C: Comparative Pharmacology. 62:101-105
1. The stereospecificity of the interaction of the enantiomers of the anticoagulent drugs warfarin and phenprocoumon with bovine and rat serum albumin was investigated using equilibrium dialysis and circular dichroism measurements and compared with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78a046b4a45169dca68df3728b7132e9
https://doi.org/10.1016/0306-4492(79)90107-2
https://doi.org/10.1016/0306-4492(79)90107-2
Publikováno v:
Clinical Pharmacology & Therapeutics. 26:196-204
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb8f4be56969373ae39dcd9f75e9ca7
https://doi.org/10.1002/cpt1979262196
https://doi.org/10.1002/cpt1979262196
Publikováno v:
Journal of Pharmacy and Pharmacology. 32:828-832
The anticoagulant activity and the pharmacokinetics of phenprocoumon as well as the effect of phenprocoumon on the vitamin K1-epoxide cycle in younger (12 weeks) and older (36 weeks) male inbred Lewis rats has been examined in a study of the mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd83c09f7ccb5f44d9bf9e3f6242746e
https://doi.org/10.1111/j.2042-7158.1980.tb13085.x
https://doi.org/10.1111/j.2042-7158.1980.tb13085.x
Publikováno v:
British Journal of Clinical Pharmacology. 5:437-440
1 The elimination and anticoagulant activity of a single intravenous dose of warfarin (1.0-1.2 mg/kg) without and with concomitant cholestyramine treatment (about 4 g three times daily) was studied in five healthy male subjects. 2 Cholestyramine trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eae5cd8d482db837887da80a20cc87e
https://doi.org/10.1111/j.1365-2125.1978.tb01651.x
https://doi.org/10.1111/j.1365-2125.1978.tb01651.x