Zobrazeno 1 - 10
of 264
pro vyhledávání: '"Eberhard, Fuchs"'
Autor:
Christopher R. Pryce, Eberhard Fuchs
Publikováno v:
Neurobiology of Stress, Vol 6, Iss C, Pp 94-103 (2017)
Human psychological stress is the major environmental risk factor for major depression and certain of the anxiety disorders. Psychological stressors often occur in the context of the adult social environment, and they or the memory formed of them imp
Externí odkaz:
https://doaj.org/article/95f953bdf668460a94a5ede87eb58bd3
Publikováno v:
Neurobiology of Aging.
Astrocytes perform multiple essential functions in the brain showing morphological changes. Hypertrophic astrocytes are commonly observed in cognitively healthy aged animals, implying a functional defense mechanism without losing neuronal support. In
Autor:
Pia Runeberg-Roos, Elisa Piccinini, Anna-Maija Penttinen, Kert Mätlik, Hanna Heikkinen, Satu Kuure, Maxim M. Bespalov, Johan Peränen, Enrique Garea-Rodríguez, Eberhard Fuchs, Mikko Airavaara, Nisse Kalkkinen, Richard Penn, Mart Saarma
Publikováno v:
Neurobiology of Disease, Vol 96, Iss , Pp 335-345 (2016)
In Parkinson's disease midbrain dopaminergic neurons degenerate and die. Oral medications and deep brain stimulation can relieve the initial symptoms, but the disease continues to progress. Growth factors that might support the survival, enhance the
Externí odkaz:
https://doaj.org/article/a3f501f9389e4ae69124b3f661ad8d55
Autor:
Enrique Garea-Rodríguez, Ave Eesmaa, Päivi Lindholm, Christina Schlumbohm, Jessica König, Birgit Meller, Kerstin Krieglstein, Gunther Helms, Mart Saarma, Eberhard Fuchs
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149776 (2016)
Cerebral dopamine neurotrophic factor (CDNF) belongs to a newly discovered family of evolutionarily conserved neurotrophic factors. We demonstrate for the first time a therapeutic effect of CDNF in a unilateral 6-hydroxydopamine (6-OHDA) lesion model
Externí odkaz:
https://doaj.org/article/14d249fd12634f47b5c7f152ba82e417
Autor:
Eberhard Fuchs, Alejandro García-Carrancá, Abraham Rosas-Arellano, Fanis Missirlis, Rubén G. Contreras, M. Estela Albino-Sánchez, Claudia Perez-Cruz, Raúl Antonio Maqueda-Alfaro, Juan D. Rodriguez-Callejas, Argel Estrada-Mondragón, Catalina Flores-Maldonado, Ismael León-Galicia
Publikováno v:
Neuroscience. 439:275-286
The use of antibodies to identify neuronal receptors, neurotransmitters, cytoskeletal elements or pathologic protein aggregates, ion channels, adhesion molecules or other cell-type specific markers, is common practice in neuroscience. Antibody detect
Publikováno v:
Borbély, É, Simon, M, Fuchs, E, Wiborg, O, Czéh, B & Helyes, Z 2022, ' Novel drug developmental strategies for treatment-resistant depression ', British Journal of Pharmacology, vol. 179, no. 6, pp. 1146-1186 . https://doi.org/10.1111/bph.15753
Major depressive disorder is a leading cause of disability worldwide. Because conventional therapies are ineffective in many patients, novel strategies are needed to overcome treatment-resistant depression (TRD). Limiting factors of successful drug d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b74c4dee7bc40917e8a3bb8323d5513a
https://vbn.aau.dk/da/publications/f1e3fcbc-76f1-4232-85f6-3489716b951c
https://vbn.aau.dk/da/publications/f1e3fcbc-76f1-4232-85f6-3489716b951c
Autor:
Eberhard Fuchs, Gabriele Flügge
Publikováno v:
Neural Plasticity, Vol 2014 (2014)
Within the last four decades, our view of the mature vertebrate brain has changed significantly. Today it is generally accepted that the adult brain is far from being fixed. A number of factors such as stress, adrenal and gonadal hormones, neurotrans
Externí odkaz:
https://doaj.org/article/95bd3183d67e4f05a83dba0acdc06127
Autor:
Sophie Seehase, Hans-Dieter Lauenstein, Christina Schlumbohm, Simone Switalla, Vanessa Neuhaus, Christine Förster, Hans-Gerd Fieguth, Olaf Pfennig, Eberhard Fuchs, Franz-Josef Kaup, Martina Bleyer, Jens M Hohlfeld, Armin Braun, Katherina Sewald, Sascha Knauf
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43709 (2012)
Increasing incidence and substantial morbidity and mortality of respiratory diseases requires the development of new human-specific anti-inflammatory and disease-modifying therapeutics. Therefore, new predictive animal models that closely reflect hum
Externí odkaz:
https://doaj.org/article/00b83f08b413464991b7d932bdd429ff
Publikováno v:
PLoS ONE, Vol 4, Iss 1, p e3659 (2009)
It has been repeatedly shown that chronic stress changes dendrites, spines and modulates expression of synaptic molecules. These effects all may impair information transfer between neurons. The present study shows that chronic stress also regulates e
Externí odkaz:
https://doaj.org/article/f6f5f30bd08f49a4a0e79eeafa49db98
Autor:
Claudia Perez-Cruz, Jeanine I. H. Müller-Keuker, Urs Heilbronner, Eberhard Fuchs, Gabriele Flügge
Publikováno v:
Neural Plasticity, Vol 2007 (2007)
The prefrontal cortex (PFC) plays an important role in the stress response. We filled pyramidal neurons in PFC layer III with neurobiotin and analyzed dendrites in rats submitted to chronic restraint stress and in controls. In the right prelimbic cor
Externí odkaz:
https://doaj.org/article/38d13c729a474147b151c8c98438274a