Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ebe Schiavo"'
Autor:
Ebe Schiavo, Beatrice Martini, Enrico Attardi, Filippo Consonni, Sara Ciullini Mannurita, Maria Luisa Coniglio, Marco Tellini, Elena Chiocca, Ilaria Fotzi, Laura Luti, Irene D’Alba, Marinella Veltroni, Claudio Favre, Eleonora Gambineri
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Inborn errors of immunity (IEI) are genetic disorders characterized by a wide spectrum of clinical manifestations, ranging from increased susceptibility to infections to significant immune dysregulation. Among these, primary immune regulatory disorde
Externí odkaz:
https://doaj.org/article/4716a7f1014944e8b9bdbe5d2196291b
Autor:
Sara Ciullini Mannurita, Rayan Goda, Ebe Schiavo, Maria Luisa Coniglio, Annachiara Azzali, Ilaria Fotzi, Annalisa Tondo, Veronica Tintori, Stefano Frenos, Maria Chiara Sanvito, Marina Vignoli, Cristina Luceri, Elisabetta Bigagli, Alessia Grassi, Mario Milco D’Elios, Claudio Favre, Eleonora Gambineri
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
STAT3 gain-of-function (GOF) mutations can be responsible for an incomplete phenotype mainly characterized by hematological autoimmunity, even in the absence of other organ autoimmunity, growth impairment, or severe infections. We hereby report a cas
Externí odkaz:
https://doaj.org/article/7f96b3b974ce4ad7b60dbe104167cec9
Autor:
Filippo Consonni, Francesco Pegoraro, Giorgio Costagliola, Beatrice Martini, Ebe Schiavo, Annalisa Legitimo, Coniglio Maria Luisa, Claudio Favre, Marinella Veltroni, Eleonora Gambineri
Publikováno v:
Clinical Immunology. 250:109433
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a82543a1da8d1135e0d68a9dcfb72eab
https://doi.org/10.1016/j.clim.2023.109433
https://doi.org/10.1016/j.clim.2023.109433
Autor:
Ebe Schiavo, Cristina Luceri, Rayan Goda, Eleonora Gambineri, Claudio Favre, Elisabetta Bigagli, Alessia Grassi, Marina Vignoli, Annachiara Azzali, Mario Milco D'Elios, Annalisa Tondo, Maria Chiara Sanvito, Ilaria Fotzi, Sara Ciullini Mannurita, Veronica Tintori, Stefano Frenos, Maria Luisa Coniglio
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2021)
Frontiers in Immunology, Vol 11 (2021)
STAT3 gain-of-function (GOF) mutations can be responsible for an incomplete phenotype mainly characterized by hematological autoimmunity, even in the absence of other organ autoimmunity, growth impairment, or severe infections. We hereby report a cas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ebdd74decf7b7de4023aa9556d42ae1
https://hdl.handle.net/11365/1220445
https://hdl.handle.net/11365/1220445
Autor:
Bernardo Reina-San-Martin, Pedro P. Rocha, Anne-Sophie Thomas-Claudepierre, Jane A. Skok, Isabelle Robert, Vincent M. Luo, Tilman Borggrefe, Ebe Schiavo, Janardan K. Reddy, Richard Bonneau, Vincent Heyer, Ramya Raviram
Publikováno v:
The Journal of Experimental Medicine
Thomas-Claudepierre et al. report that mediator facilitates the long-range contacts between acceptor switch regions and the IgH locus enhancers during class switch recombination and their transcriptional activation.
Immunoglobulin (Ig) class swi
Immunoglobulin (Ig) class swi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc1120f3a66752cdfe8ea9230b0471ba
http://europepmc.org/articles/PMC4813673
http://europepmc.org/articles/PMC4813673
Autor:
Vincent Heyer, Bernardo Reina-San-Martin, Ebe Schiavo, Léa Gaudot, Anne-Sophie Thomas-Claudepierre, Isabelle Robert
Publikováno v:
European Journal of Immunology
European Journal of Immunology, 2018, 48 (4), pp.720-723. ⟨10.1002/eji.201747258⟩
European Journal of Immunology, 2018, 48 (4), pp.720-723. ⟨10.1002/eji.201747258⟩
The Mediator complex is known to orchestrate transcription. Here we show that B cell conditional deficient mice for the Med1 subunit display robust somatic hypermutation. Nevertheless, the mutation frequency at A residues is decreased and the expecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ebd5a1b51e4ce9fc5e6809783b8fdc6
https://hal.science/hal-03671896
https://hal.science/hal-03671896
Autor:
Maria T. Simon, Isabelle Robert, Vincent Heyer, Kerstin-Maike Schmitz, Sara Milosevic, Sarah L. Maslen, Mark Skehel, Katharina L. Willmann, Siim Pauklin, Bernardo Reina-San-Martin, Gopinath Rangam, Svend K. Petersen-Mahrt, Ebe Schiavo
Publikováno v:
The Journal of Experimental Medicine
Antibody diversification requires the DNA deaminase AID to induce DNA instability at immunoglobulin (Ig) loci upon B cell stimulation. For efficient cytosine deamination, AID requires single-stranded DNA and needs to gain access to Ig loci, with RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477198828b4f1fc2c142ab7964ac520e
https://doi.org/10.1084/jem.20112145
https://doi.org/10.1084/jem.20112145
Autor:
Ebe Schiavo, Adeline Page, Isabelle Robert, Vincent Heyer, Marjorie Fournier, Bernardo Reina-San-Martin, Anne-Sophie Thomas-Claudepierre
Publikováno v:
The Journal of Experimental Medicine
The cohesin complex is recruited to DNA switch regions and is required for nonhomologous end joining during immunoglobulin class switch recombination.
Immunoglobulin (Ig) class switch recombination (CSR) is initiated by the transcription-coupled
Immunoglobulin (Ig) class switch recombination (CSR) is initiated by the transcription-coupled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::529f80f4815fcecb3a8dad299345241e
https://pubmed.ncbi.nlm.nih.gov/24145512
https://pubmed.ncbi.nlm.nih.gov/24145512
Autor:
Daniela Benati, Micol Ferro, Cosima T. Baldari, Franco Laghi Pasini, Maria Teresa Savino, Annalisa Nuccitelli, Cristina Ulivieri, Ebe Schiavo
Publikováno v:
Journal of leukocyte biology. 87(3)
By impairing prenylation of Ras-related GTPases, simvastatin blocks phagocytosis and oxidative burst while enhancing production of proinflammatory mediators in human macrophages challenged with IgG-coated bacteria. Besides lowering circulating choles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e4b4d297a53fb4ef9af4952aaedbc2d
https://pubmed.ncbi.nlm.nih.gov/19892847
https://pubmed.ncbi.nlm.nih.gov/19892847