Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Eavan McLoughlin"'
Autor:
Tarek S. Ibrahim, Mohamed M. Hawwas, Azizah M. Malebari, Ehab S. Taher, Abdelsattar M. Omar, Niamh M. O'Boyle, Eavan McLoughlin, Zakaria K. Abdel-Samii, Yaseen A. M. M. Elshaier
Publikováno v:
Pharmaceuticals, Vol 13, Iss 11, p 393 (2020)
A novel series of quinoline derivatives of combretastatin A-4 incorporating rigid hydrazone and a cyclic oxadiazole linkers were synthesized and have demonstrated potent tubulin polymerization inhibitory properties. Many of these novel derivatives ha
Externí odkaz:
https://doaj.org/article/19ebe3e124bc42398900ea3767719fa5
Autor:
Dervla Kelly, Aaron Koay, Gabriela Mineva, Monika Volz, Aoibhin McCool, Eavan McLoughlin, Ruán Ó Conluain, Manuj Sharma, Aisling Kerr, Bryony Dean Franklin, Tamasine Grimes
Publikováno v:
Public Health. 214:50-60
Public health emergencies (PHE) can disrupt personal medication practices and increase the risk of medication-related harm and other negative medication-related outcomes. Our aim was to examine the extent and nature of published research on this topi
Autor:
Samuel BERTRAND, Francesca Giuntini, Vânia Moreira, Niamh O'Boyle, Pascal Marchand, Florence McCarthy, Susan E Matthews, Laura Carro, Christophe Rochais, Jean-Jacques HELESBEUX, Eavan McLoughlin, Gülşah Bayraktar
Publikováno v:
Pharmaceuticals
Pharmaceuticals, Vol 14, Iss 1278, p 1278 (2021)
Pharmaceuticals, Vol 14, Iss 1278, p 1278 (2021)
The 29th Annual GP2A (Group for the Promotion of Pharmaceutical chemistry in Academia) Conference was a virtual event this year due to the COVID-19 pandemic and spanned three days from Wednesday 25 to Friday 27 August 2021. The meeting brought togeth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba269fe8f3b0b7a536c0afc5af6f2c8
https://ueaeprints.uea.ac.uk/id/eprint/82764/
https://ueaeprints.uea.ac.uk/id/eprint/82764/
Publikováno v:
Proceedings of 7th International Electronic Conference on Medicinal Chemistry.
Autor:
Eavan McLoughlin, Niamh M. O’Boyle
Publikováno v:
Proceedings of 6th International Electronic Conference on Medicinal Chemistry.
The combretastatins are diaryl stilbenoid natural products isolated from the bark of the South African willow tree Combretum caffrum. CA-4 is a potent anticancer agent, which inhibits cancer cell proliferation and microtubule polymerisation by bindin
Autor:
Eavan McLoughlin, Abdelsattar M. Omar, Tarek S. Ibrahim, Mohamed M Hawwas, Azizah M. Malebari, Niamh M. O’Boyle, Zakaria K. Abdel-Samii, Ehab S. Taher, Yaseen A.M.M. Elshaier
Publikováno v:
Pharmaceuticals
Volume 13
Issue 11
Pharmaceuticals, Vol 13, Iss 393, p 393 (2020)
Volume 13
Issue 11
Pharmaceuticals, Vol 13, Iss 393, p 393 (2020)
A novel series of quinoline derivatives of combretastatin A-4 incorporating rigid hydrazone and a cyclic oxadiazole linkers were synthesized and have demonstrated potent tubulin polymerization inhibitory properties. Many of these novel derivatives ha
Autor:
Niamh M. O’Boyle, Eavan McLoughlin
Publikováno v:
Pharmaceuticals, Vol 13, Iss 72, p 72 (2020)
Erratum for Colchicine-Binding Site Inhibitors from Chemistry to Clinic: A Review. McLoughlin EC, O'Boyle NM. Pharmaceuticals (Basel). 2020 Jan 3;13(1):8. doi: 10.3390/ph13010008.
Autor:
Eavan McLoughlin, Niamh M. O’Boyle
Publikováno v:
Pharmaceuticals
Pharmaceuticals, Vol 13, Iss 1, p 8 (2020)
Pharmaceuticals, Vol 13, Iss 1, p 8 (2020)
It is over 50 years since the discovery of microtubules, and they have become one of the most important drug targets for anti-cancer therapies. Microtubules are predominantly composed of the protein tubulin, which contains a number of different bindi
Publikováno v:
Proceedings of 5th International Electronic Conference on Medicinal Chemistry.
Combretastatin A-4 (CA-4) is the most potent antimitotic agent of the Combretastatin A series; a group of diaryl stilbenes isolated from the wood of the South African tree Combretum caffrum. [i] It has significant anticancer activity through inhibiti