Zobrazeno 1 - 10
of 1 287
pro vyhledávání: '"Early onset Alzheimer's disease"'
Publikováno v:
Неврология, нейропсихиатрия, психосоматика, Vol 16, Iss 2, Pp 95-100 (2024)
Alzheimer's disease (AD) is the most common degenerative disease of the brain leading to dementia. AD is the most common cause of disability among age-related diseases. The diagnosis of AD is based on clinical findings and is confirmed by the presenc
Externí odkaz:
https://doaj.org/article/625757962c0a4e3a94ad7a41ca8286cb
Autor:
Hui Hong, Yutong Chen, Weiran Liu, Xiao Luo, Minming Zhang, for the Alzheimer's Disease Neuroimaging Initiative (ADNI)
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 2, Pp n/a-n/a (2024)
Abstract Introduction The distribution of voxel‐ and connection‐based white matter hyperintensity (WMH) patterns in early‐onset Alzheimer's disease (EOAD) and late‐onset Alzheimer's disease (LOAD), as well as factors associated with these pat
Externí odkaz:
https://doaj.org/article/eb6ed5c089d74f03876be398c13a83c6
Autor:
Phoebe Valdes, Kenneth W. Henry, Michael Q. Fitzgerald, Koushik Muralidharan, Andrew B. Caldwell, Srinivasan Ramachandran, Lawrence S. B. Goldstein, William C. Mobley, Douglas R. Galasko, Shankar Subramaniam
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-8 (2023)
Abstract Non-familial Alzheimer’s disease (AD) occurring before 65 years of age is commonly referred to as early-onset Alzheimer’s disease (EOAD) and constitutes ~ 5–6% of all AD cases (Mendez et al. in Continuum 25:34–51, 2019). While EOAD e
Externí odkaz:
https://doaj.org/article/3ea7c071f924471b9c2a68f75dab7070
Autor:
William G. Mantyh, J. Nicholas Cochran, Jared W. Taylor, Iris J. Broce, Ethan G. Geier, Luke W. Bonham, Ashlyn G. Anderson, Daniel W. Sirkis, Renaud La Joie, Leonardo Iaccarino, Kiran Chaudhary, Lauren Edwards, Amelia Strom, Harli Grant, Isabel E. Allen, Zachary A. Miller, Marilu L. Gorno‐Tempini, Joel H. Kramer, Bruce L. Miller, Rahul S. Desikan, Gil D. Rabinovici, Jennifer S. Yokoyama
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 4, Pp n/a-n/a (2023)
Abstract Early‐onset Alzheimer's disease (AD) is highly heritable, yet only 10% of cases are associated with known pathogenic mutations. For early‐onset AD patients without an identified autosomal dominant cause, we hypothesized that their early
Externí odkaz:
https://doaj.org/article/4906107fb48d48b98f50a0cb0d77e800
Akademický článek
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Publikováno v:
Неврология, нейропсихиатрия, психосоматика, Vol 14, Iss 2, Pp 110-116 (2022)
Alzheimer's disease (AD) is the most common cause of cognitive impairment in adults. There are two main forms of AD: early-onset (onset before 65 years) and late-onset (onset after 65 years). Early-onset AD accounts for at least 5% of all disease cas
Externí odkaz:
https://doaj.org/article/be6d65a4abfa4859a3528c191255271e
Publikováno v:
BMC Rheumatology, Vol 6, Iss 1, Pp 1-12 (2022)
Abstract Background There is increasing research focus on prediction and prevention of rheumatoid arthritis (RA). Information about risk of RA is increasingly available via direct-to-consumer testing. However, there is limited understanding of public
Externí odkaz:
https://doaj.org/article/d6a5818de340457f9fbfd839d0f5a4f6
Autor:
Gonzalo Forno, Manojkumar Saranathan, Jose Contador, Nuria Guillen, Neus Falgàs, Adrià Tort-Merino, Mircea Balasa, Raquel Sanchez-Valle, Michael Hornberger, Albert Lladó
Publikováno v:
Current Research in Neurobiology, Vol 4, Iss , Pp 100084- (2023)
Alzheimer's disease (AD) is the most common cause of dementia worldwide. Increasing evidence points to the thalamus as an important hub in the clinical symptomatology of the disease, with the ‘limbic thalamus’ been described as especially vulnera
Externí odkaz:
https://doaj.org/article/3ddd4cc545cc42549b51a08bd5257f12
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
TANK1-binding kinase 1 (TBK1) is mainly involved in the regulation of various cellular pathways through the autophagic lysosomal system, and the loss of function or hypofunction caused by TBK1 gene mutation mainly leads to frontotemporal lobar degene
Externí odkaz:
https://doaj.org/article/577e1543dfc14d798bdaad4bb35e1068
Akademický článek
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