TCR signal strength controls thymic differentiation of iNKT cell subsets

Autor: Kent Riemondy, Anjana Rao, Brian P. O'Connor, S. Harsha Krovi, Laurent Gapin, Adam R. Lefferts, Jay R. Hesselberth, Leonard L. Dragone, Catherine Halluszczak, Philippa Marrack, Jingjing Zhang, Lisa K. Peterson, Kathryn D. Tuttle, Laura Harmacek, James P. Scott-Browne, Romain Bedel

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications
Nature communications, vol. 9, no. 1, pp. 2650

During development in the thymus, invariant natural killer T (iNKT) cells commit to one of three major functionally different subsets, iNKT1, iNKT2, and iNKT17. Here, we show that T cell antigen receptor (TCR) signal strength governs the development

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f89e4c35d3becfa75c6b45c62a82a633
http://link.springer.com/article/10.1038/s41467-018-05026-6