Zobrazeno 1 - 10
of 1 005
pro vyhledávání: '"Early Cancer Detection"'
Publikováno v:
Advanced Science, Vol 11, Iss 30, Pp n/a-n/a (2024)
Abstract Cell‐free DNA (cfDNA) fragmentation patterns have immense potential for early cancer detection. However, the definition of fragmentation varies, ranging from the entire genome to specific genomic regions. These patterns have not been syste
Externí odkaz:
https://doaj.org/article/6834aeb9d3b34f918d64ea91979e7895
Autor:
Zurong Wan, Jinghua Gu, Uthra Balaji, Linda Bojmar, Henrik Molina, Søren Heissel, Alexandra E. Pagano, Christopher Peralta, Lee Shaashua, Dorina Ismailgeci, Hope K. Narozniak, Yi Song, William R. Jarnagin, David P. Kelsen, Jaqueline Bromberg, Virginia Pascual, Haiying Zhang
Publikováno v:
Journal of Extracellular Biology, Vol 3, Iss 7, Pp n/a-n/a (2024)
Abstract Circulating extracellular vesicles and particles (EVPs) are being investigated as potential biomarkers for early cancer detection, prognosis, and disease monitoring. However, the suboptimal purity of EVPs isolated from peripheral blood plasm
Externí odkaz:
https://doaj.org/article/95a9b12e918b4946b26a0313b16a23b8
Autor:
Christian Schmithals, Bianca Kakoschky, Dominic Denk, Maike von Harten, Jan Henrik Klug, Edith Hintermann, Anne Dropmann, Eman Hamza, Anne Claire Jacomin, Jens U. Marquardt, Stefan Zeuzem, Peter Schirmacher, Eva Herrmann, Urs Christen, Thomas J. Vogl, Oliver Waidmann, Steven Dooley, Fabian Finkelmeier, Albrecht Piiper
Publikováno v:
EBioMedicine, Vol 105, Iss , Pp 105178- (2024)
Summary: Background: The accuracy of blood-based early tumour recognition is compromised by signal production at non-tumoral sites, low amount of signal produced by small tumours, and variable tumour production. Here we examined whether tumour-specif
Externí odkaz:
https://doaj.org/article/697990059c5e4e25a28e59b2e57c8d91
Autor:
Stephen Murtough, Deepak Babu, Catherine M. Webb, Hélène Louis dit Picard, Lisa A. McGinty, Jennifer Chao-Chu, Ryan Pink, Andrew R. Silver, Howard L. Smart, John K. Field, Philip Woodland, Janet M. Risk, Diana C. Blaydon, Daniel J. Pennington, David P. Kelsell
Publikováno v:
Gastro Hep Advances, Vol 3, Iss 3, Pp 385-395 (2024)
Background and Aims: Survival rates for esophageal squamous cell carcinoma (ESCC) are extremely low due to the late diagnosis of most cases. An understanding of the early molecular processes that lead to ESCC may facilitate opportunities for early di
Externí odkaz:
https://doaj.org/article/a85cc09e91124fee910a8d340d8707ab
Publikováno v:
Biomedicines, Vol 12, Iss 11, p 2546 (2024)
Cancer remains a leading cause of mortality in Japan, yet participation in conventional screening programs is low due to invasiveness, cost, and accessibility. Non-invasive, affordable, and accurate methods for early cancer detection in asymptomatic
Externí odkaz:
https://doaj.org/article/b6f154a942f8457aaa8043b24d1abbb0
Autor:
Floriana Porcaro, Antonella Paolucci, Piercarmine Porcaro, Gaetano Cardinale, Antonia Romitelli, Domenico Cozzolino, Serena Voccola
Publikováno v:
Diagnostics, Vol 14, Iss 22, p 2575 (2024)
Endometrial cancer (EC) is the most common gynecological malignancy, with rising incidence and mortality rates. Key risk factors, including obesity, prolonged estrogen exposure, and metabolic disorders, underscore the urgent need for non-invasive, ea
Externí odkaz:
https://doaj.org/article/babedd196672447991dc5822664fd1e4
Autor:
Maajid Mohi Ud Din Malik, Mansour M. Alqahtani, Ibrahim Hadadi, Ibrahem Kanbayti, Zeyad Alawaji, Bader A. Aloufi
Publikováno v:
Diagnostics, Vol 14, Iss 21, p 2459 (2024)
Background: Early cancer detection is crucial for improving patient outcomes. Molecular imaging biomarkers offer the potential for non-invasive, early-stage cancer diagnosis. Objectives: To evaluate the effectiveness and accuracy of molecular imaging
Externí odkaz:
https://doaj.org/article/45f5cd3c8d7a4e1fac3114b5de7d6455
Publikováno v:
The Lancet Regional Health. Europe, Vol 32, Iss , Pp 100700- (2023)
Summary: Background: Methods to identify patients at increased risk of oesophageal cancer are needed to better identify those for targeted screening. We aimed to derive and validate novel risk prediction algorithms (CanPredict) to estimate the 10-yea
Externí odkaz:
https://doaj.org/article/77545859512c432f9bd3c7cc0e880e1e
Autor:
Chun Ning, Peng Cai, Xiaofan Liu, Guangtao Li, Pengfei Bao, Lu Yan, Meng Ning, Kaichen Tang, Yi Luo, Hua Guo, Yunjiu Wang, Zhuoran Wang, Lu Chen, Zhi John Lu, Jianhua Yin
Publikováno v:
EBioMedicine, Vol 93, Iss , Pp 104645- (2023)
Summary: Background: Various studies have reported cell-free RNAs (cfRNAs) as noninvasive biomarkers for detecting hepatocellular carcinoma (HCC). However, they have not been independently validated, and some results are contradictory. We provided a
Externí odkaz:
https://doaj.org/article/86889a7807f0485caefb537ca288021f
Publikováno v:
Chemosensors, Vol 12, Iss 3, p 44 (2024)
Gastric cancer (GC) remains a significant global health challenge, with late-stage diagnosis impacting treatment options and decreased survival rates. To address this, there has been a growing interest in the development of innovative screening and d
Externí odkaz:
https://doaj.org/article/6638163f3aa94fd9a091e9ce932eef74