Zobrazeno 1 - 10 of 48 pro vyhledávání: '"Earle W. Holmes"'
1
An interactive website for analytical method comparison and bias estimation
Autor: Ayse F. Tuncel, Burak Bahar, Earle W. Holmes, Daniel T. Holmes
Publikováno v: Clinical Biochemistry. 50:1025-1029
Objectives Regulatory standards mandate laboratories to perform studies to ensure accuracy and reliability of their test results. Method comparison and bias estimation are important components of these studies. Design & methods We developed an intera
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c586b4ca869402b981d6d151d1c7227
https://doi.org/10.1016/j.clinbiochem.2017.08.008
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4
BIOTIN INTERFERENCE WITH ROUTINE CLINICAL IMMUNOASSAYS: UNDERSTAND THE CAUSES AND MITIGATE THE RISKS
Autor: Farah Meah, Earle W. Holmes, Shanika Samarasinghe, Arshi Basit, Vinita Singh, Mary Ann Emanuele, Alaleh Mazhari, Nicholas V. Emanuele
Publikováno v: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 23(8)
Objective: The objectives of this report are to review the mechanisms of biotin interference with streptavidin/biotin-based immunoassays, identify automated immunoassay systems vulnerable to biotin interference, describe how to estimate and minimize
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c847fd02ab190c8583e259dfcb36b5f
https://pubmed.ncbi.nlm.nih.gov/28534685
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5
Analytical Variability Among Methods for the Measurement of 25-Hydroxyvitamin D
Autor: Jean Garbincius, Kathleen M. McKenna, Earle W. Holmes
Publikováno v: American Journal of Clinical Pathology. 140:550-560
Objectives: To compare total 25-hydroxyvitamin D [25(OH) D] results measured by 3 direct immunoassays, including the previous version of the DiaSorin Liaison2 assay and the current versions of the Siemens Centaur2 and the Abbott Architect assays, wit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::705aa25aa634a94cf41c70e624c0b973
https://doi.org/10.1309/ajcpu2skw1tfkswy
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6
Identification of patients with low-risk for aneuploidy: Comparative discriminatory models using linear and machine-learning classifiers in prostate cancer
Autor: David G. Bostwick, Gladell P. Paner, Eva M. Wojcik, Girish Venkataraman, Earle W. Holmes, Vijayalakshmi Ananthanarayanan, Robert C. Flanigan, Georg Heinze, Carrie M. Bradford-De La garza, Henry G. Brown
Publikováno v: The Prostate. 67:1524-1536
BACKGROUND Prostate needle biopsy (PNB) ploidy status has proven utility to predict adverse outcomes after prostatectomy. We sought to develop models to predict ploidy status using clinicopathologic variables. METHODS We identified a cohort of 169 pa
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https://doi.org/10.1002/pros.20629
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7
Gas chromatographic method for detection of urinary sucralose: application to the assessment of intestinal permeability
Autor: Earle W. Holmes, Lei Zhang, Ashkan Farhadi, Ali Banan, Jeremy Z. Fields, Ali Keshavarzian
Publikováno v: Journal of Chromatography B. 784:145-154
We developed a capillary column gas chromatography (CCGC) method for the measurement of urinary sucralose (S) and three other sugar probes including, sucrose, lactulose (L) and mannitol (M) for use in in vivo studies of intestinal permeability. We co
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b8c46e017042ad3db50ec011be4a260
https://doi.org/10.1016/s1570-0232(02)00787-0
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8
Hepatic Expression of Polymerase β, Ref-1, PCNA, and Bax in WY 14,643-Exposed Rats and Hamsters
Autor: Earle W. Holmes, M.L. Cunningham, C.M. Bingham
Publikováno v: Experimental and Molecular Pathology. 73:209-219
The hepatic levels of three protein markers of oxidative stress, polymerase beta, Ref-1, and PCNA, and of the pro-apoptotic protein, Bax, were quantitated after exposure to WY 14,643 (500 ppm in the feed) for 6 or 34 days in a rodent that is suscepti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e9905991569518f6a04b10bd90c76f9
https://doi.org/10.1006/exmp.2002.2477
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9
Synthetic melanin polymers with antithrombotic activity (833.3)
Autor: Earle W. Holmes
Publikováno v: The FASEB Journal. 28
I evaluated the anticoagulant properties of a family of novel water soluble melanin polymers (Mels) synthesized by a patented process (12/809,369). Mels were screened for activity in standard assay...
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https://doi.org/10.1096/fasebj.28.1_supplement.833.3
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10
Exacerbation of Alcoholic Liver Injury by Enteral Endotoxin in Rats
Autor: Hidekazu Tsukamoto, Sandeep Choudhary, Earle W. Holmes, Qinggao Deng, Philippe Mathurin, Ali Keshavarzian
Publikováno v: Hepatology. 32:1008-1017
Increased gut permeability (leaky gut) and endotoxin-mediated Kupffer cell activation are proposed as the mechanisms of alcoholic liver injury. Although ethanol feeding is shown to sensitize the liver for injury induced by parental administration of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db57e94ab1a845a1a81ccacdcaa8ad25
https://doi.org/10.1053/jhep.2000.19621
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