Výsledky vyhledávání - "Earl St. Rose"

Akademický článek

24-h bronchodilation and inspiratory capacity improvements with glycopyrrolate/formoterol fumarate via co-suspension delivery technology in COPD

Autor: Colin Reisner, Gregory Gottschlich, Faisal Fakih, Andras Koser, James Krainson, Luis Delacruz, Samir Arora, Gregory Feldman, Krishna Pudi, Shahid Siddiqui, Chad Orevillo, Andrea Maes, Earl St. Rose, Ubaldo Martin

Publikováno v: Respiratory Research, Vol 18, Iss 1, Pp 1-11 (2017)

Abstract Background Symptoms of chronic obstructive pulmonary disease may vary throughout the day and it is important that therapeutic approaches provide 24-h symptom control. We report the results of two phase IIIb crossover studies, PT003011 and PT

Externí odkaz: https://doaj.org/article/411f6d54c236445c801f43ed633faa2b

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Reduced All-Cause Mortality in the ETHOS Trial of Budesonide/Glycopyrrolate/Formoterol for Chronic Obstructive Pulmonary Disease. A Randomized, Double-Blind, Multicenter, Parallel-Group Study

Autor: Gary T. Ferguson, Kimberly Rossman, Dave Singh, Roopa Trivedi, Earl St Rose, Shaila Ballal, Paul Dorinsky, Fernando J. Martinez, Magnus Aurivillius, Patrick Darken, Colin Reisner, Klaus F. Rabe, Jadwiga A. Wedzicha, Chen Wang

Publikováno v: American Journal of Respiratory and Critical Care Medicine

Rationale: In the phase III, 52-week ETHOS (Efficacy and Safety of Triple Therapy in Obstructive Lung Disease) trial in chronic obstructive pulmonary disease (COPD) (NCT02465567), triple therapy with budesonide/glycopyrrolate/formoterol fumarate (BGF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a1058cbdb73d18dbf60fe345e32e86a
http://europepmc.org/articles/PMC7924571

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An Open-Label Study Evaluating the Performance of the Dose Indicator in a Metered Dose Inhaler Delivering Glycopyrrolate and Formoterol Fumarate in Patients with Moderate-to-Very Severe Chronic Obstructive Pulmonary Disease

Autor: Earl St Rose, Shahid Siddiqui, Gregory Feldman, Peter Mack, Colin Reisner, Krishna Pudi, Faisal Fakih, Andrea Maes

Publikováno v: Journal of Aerosol Medicine and Pulmonary Drug Delivery

Background: GFF MDI is a glycopyrrolate/formoterol fumarate fixed-dose combination metered dose inhaler formulated using co-suspension delivery technology. This open-label, single-arm multicenter study (NCT02268396) evaluated the accuracy, reliabilit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::328aaaf93915999d39b28285f24c7493
http://europepmc.org/articles/PMC6354605

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COPD exacerbation rates by month in the ETHOS trial with budesonide/glycopyrronium/formoterol metered dose inhaler (BGF MDI) at two ICS dose levels

Autor: Paul Dorinsky, Roopa Trivedi, Patrick Darken, Jadwiga A. Wedzicha, Earl St Rose, Colin Reisner, Chen Wang, Magnus Aurivillius, Shaila Ballal, Dave Singh, Klaus F. Rabe, Gary T. Ferguson, J. McLaren, Fernando J. Martinez

Publikováno v: Airway pharmacology and treatment.

Background: In the 52-week ETHOS trial (NCT02465567), the triple fixed-dose combination BGF MDI containing 320 µg or 160 µg budesonide reduced the rate of moderate/severe COPD exacerbations vs dual therapies. Objective: To assess exacerbation rates

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f9d0d65c45bebb1c60808b633c7b865d
https://doi.org/10.1183/13993003.congress-2020.977

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Functional respiratory imaging assessment of glycopyrrolate and formoterol fumarate metered dose inhalers formulated using co-suspension delivery technology in patients with COPD

Autor: Ilse Verlinden, Martin Jenkins, Ubaldo J. Martin, Dianne Griffis, Glenn Leemans, Jan De Backer, Earl St Rose, Jane Fitzpatrick, Stefan Ivanov, Wilfried De Backer, Colin Reisner, Cedric Van Holsbeke, Benjamin Mignot

Publikováno v: Therapeutic advances in respiratory disease
Therapeutic Advances in Respiratory Disease, Vol 14 (2020)
Therapeutic Advances in Respiratory Disease

Background: Functional respiratory imaging (FRI) is a quantitative postprocessing imaging technique used to assess changes in the respiratory system. Using FRI, we characterized the effects of the long-acting muscarinic antagonist (LAMA), glycopyrrol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7542a3069fc28a04ac659a565058bb22
https://hdl.handle.net/10067/1702910151162165141

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Efficacy and safety of four doses of glycopyrrolate/formoterol fumarate delivered via a metered dose inhaler compared with the monocomponents in patients with moderate-to-severe COPD

Autor: Patrick Darken, Earl St Rose, James Pearle, Colin Reisner, Edward Kerwin

Publikováno v: International Journal of Chronic Obstructive Pulmonary Disease

Colin Reisner,1,2 James Pearle,3 Edward M Kerwin,4 Earl St Rose,1 Patrick Darken1 1Pearl – a member of the AstraZeneca Group, Morristown, NJ, USA; 2AstraZeneca, Gaithersburg, MD, USA; 3California Research Medical Group, Inc., Fullerton, CA, USA; 4C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8036b1348534f510ba6f0b445b1f49
https://doi.org/10.2147/copd.s166455

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Efficacy, safety, and pharmacokinetics of budesonide/formoterol fumarate delivered via metered dose inhaler using innovative co-suspension delivery technology in patients with moderate-to-severe COPD

Autor: Thomas Siler, Samir Arora, Patrick Darken, Colin Reisner, Earl St Rose, Edward Kerwin

Publikováno v: International Journal of Chronic Obstructive Pulmonary Disease

Edward M Kerwin,1 Thomas M Siler,2 Samir Arora,3 Patrick Darken,4 Earl St Rose,4 Colin Reisner4,5 1Clinical Research Institute of Southern Oregon, Medford, OR, USA; 2Midwest Chest Consultants, St Charles, MO, USA; 3Aventiv Research, Columbus, OH, USA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5800531c232871c996cd84e9fb3b7e
https://doi.org/10.2147/copd.s164281

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Randomized, double-blind, placebo-controlled trial to assess the efficacy and safety of three doses of co-suspension delivery technology glycopyrronium MDI in Japanese patients with moderate-to-severe COPD

Autor: Andrea Maes, Yasushi Fukushima, Shahid Siddiqui, Colin Reisner, Hisakuni Sekino, Yumiko Ide, Earl St Rose, Yuji Nakatani

Publikováno v: International Journal of Chronic Obstructive Pulmonary Disease

Yasushi Fukushima,1 Yuji Nakatani,2 Yumiko Ide,3 Hisakuni Sekino,4 Earl St Rose,5 Shahid Siddiqui,6 Andrea Maes,5 Colin Reisner5,6 1Department of Internal Medicine, Fukuwa Clinic, Tokyo, Japan; 2Department of Internal Medicine, Nakatani Hospital, Hyo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c51dbaea0fc6054adb59e6f58af2f89
http://europepmc.org/articles/PMC5905841

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