Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Earl May"'
Autor:
William Earl May, Michael MacGregor
Publikováno v:
Canadian Journal of Plant Science. 102:731-743
Annual canarygrass (Phalaris canariensis L.) has a larger response to chloride (Cl−) fertilizer than other cereal crops. This unexpected response prompted further research for unexpected interactions between Cl− and other nutrients in annual cana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19f0c8b36b0638f32eae4013ae3bd8e0
https://doi.org/10.1139/cjps-2021-0157
https://doi.org/10.1139/cjps-2021-0157
Publikováno v:
Cancer Research. 83:1426-1426
Introduction: The aberrant activation of oncogenic signaling pathways can drive tumorigenesis and malignant transformation, where deregulation of the activity of protein kinases or phosphatases can play a critical role. Several protein tyrosine phosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dabd99b7960f4e4c33d55f7f9293d2b2
https://doi.org/10.1158/1538-7445.am2023-1426
https://doi.org/10.1158/1538-7445.am2023-1426
Autor:
Earl May, William, MacGregor, Michael
Publikováno v:
Canadian Journal of Plant Science; Jun2022, Vol. 102 Issue 3, p731-743, 13p
Autor:
Timothy Broderick, Luke H. Carter, Michael D. Schaber, Robert A. Copeland, Earl May, Richard R. Gontarek, Cynthia M. Rominger, Kurt Weaver, Jingsong Yang
Publikováno v:
Archives of Biochemistry and Biophysics. 464:130-137
We have developed a highly sensitive assay of MEK-mediated ATP hydrolysis by coupling the formation of ADP to NADH oxidation through the enzymes pyruvate kinase and lactate dehydrogenase. Robust ATP hydrolysis is catalyzed by phosphorylated MEK in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::978f705b3826c473eb2569c4e4770698
https://doi.org/10.1016/j.abb.2007.04.004
https://doi.org/10.1016/j.abb.2007.04.004
Autor:
Roberta S. Batorsky, Jerry L. Adams, Shu Yun Zhang, Michael D. Schaber, Rakesh Kumar, Julie Lougheed, Thomas J. Stout, Erin Hugger, Meenhard Herlyn, David Chau, Maureen L. Ho, Ami S. Lakdawala, Earl May, Rooja G. Contractor, Jae Lee, Pearl S. Huang, Andrew K. Takle, Hieu T. Do, Lusong Luo, David M. Wilson, Michael M. Morrissey, Lifu Wang, Cynthia M. Rominger, David A. Tuveson, Alastair J. King, Denis R. Patrick, David W. Rusnak, Keiran S.M. Smalley, Florian A. Karreth
Publikováno v:
Cancer Research. 66:11100-11105
Oncogenic BRAF alleles are both necessary and sufficient for cellular transformation, suggesting that chemical inhibition of the activated mutant protein kinase may reverse the tumor phenotype. Here, we report the characterization of SB-590885, a nov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c07ce13bb3eaa1a428ffcbce4a6d18
https://doi.org/10.1158/0008-5472.can-06-2554
https://doi.org/10.1158/0008-5472.can-06-2554
Publikováno v:
Antimicrobial Agents and Chemotherapy. 49:3367-3372
A fluorescence polarization assay is described that measures the binding of fluorescently labeled erythromycin to 70S ribosomes from Escherichia coli and the displacement of the erythromycin from these ribosomes. The assay has been validated with sev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6b576f0c496f943905f57d0d4db5324
https://doi.org/10.1128/aac.49.8.3367-3372.2005
https://doi.org/10.1128/aac.49.8.3367-3372.2005
Autor:
Colin Berry, Sheraz Gul, Marie J. Mazzulla, Earl May, Martin G. Smyth, Richard Charles Brown, Andrew P. Morby, David J. Powell
Publikováno v:
Biochemical Journal. 383:551-559
DNA ligases are key enzymes involved in the repair and replication of DNA. Prokaryotic DNA ligases uniquely use NAD+ as the adenylate donor during catalysis, whereas eukaryotic enzymes use ATP. This difference in substrate specificity makes the bacte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f9c37d442556cfe12b210cdb64fb7eb
https://doi.org/10.1042/bj20040054
https://doi.org/10.1042/bj20040054
Autor:
Benjamin D. Bax, Pan F. Chan, Michael M. Hann, Michael N. Gwynn, Daniel R. Gentry, Ceri J. Lewis, Jo J. Jones, Claus Spitzfaden, Andrew P. Fosberry, Martin Hibbs, Earl May, Kristin K. Brown, Alexandre Wohlkonig, Drake S. Eggleston, Onkar M. P. Singh, Alan Joseph Hennessy, Andrew J. Theobald, Fabrice Gorrec, Martin R. Saunders, Anthony Shillings, Emma J. Jones, Carol Shen, Neil D. Pearson, Jianzhong Huang, Ilaria Giordano
Despite the success of genomics in identifying new essential bacterial genes, there is a lack of sustainable leads in antibacterial drug discovery to address increasing multidrug resistance. Type IIA topoisomerases cleave and religate DNA to regulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea159ed95a9dbead771494c8d86bdb2
https://doi.org/10.1038/nature09197
https://doi.org/10.1038/nature09197
Publikováno v:
The FASEB Journal. 21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ec387f3bc971ef611bb3650b44cce8f
https://doi.org/10.1096/fasebj.21.5.a640-d
https://doi.org/10.1096/fasebj.21.5.a640-d