Výsledky vyhledávání - "Earl L. Giller"

A 6-week randomized, double-blind, placebo-controlled, comparator referenced trial of vabicaserin in acute schizophrenia

Autor: Michael J. Detke, Sharon Rosenzweig-Lipson, Janet B. W. Williams, Earl L. Giller, John M. Kane, Joan H.Q. Shen, Danielle Popp, Yonggang Zhao

Publikováno v: Journal of Psychiatric Research. 53:14-22

Vabicaserin, a potent 5-HT2C receptor agonist, decreases nucleus accumbens extracellular dopamine levels in rats, without affecting striatal dopamine, indicating mesolimbic selectivity. This is the first study of efficacy, safety and tolerability of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bde4ea53e002c5370eab45d0b731ff91
https://doi.org/10.1016/j.jpsychires.2014.02.012

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Weight effects associated with antipsychotics: A comprehensive database analysis

Autor: Earl L. Giller, Antony Loebel, David B. Allison, Bruce Parsons, Kathryn E. Williams, Steven J. Romano, Cynthia Siu

Publikováno v: Schizophrenia Research. 110:103-110

Background Available data on atypical antipsychotic-induced weight gain are limited by a number of methodological factors. The objective of this report is to evaluate short-term ( N = 1742) and long-term ( N = 1649) weight effects in patients receivi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3eb68fadcfe2348297f0e314c804589
https://doi.org/10.1016/j.schres.2008.09.025

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Comparison of Site-Based Versus Central Ratings in a Study of Generalized Anxiety Disorder

Autor: Lisa Curry, Michael J. Detke, Janet B. W. Williams, Earl L. Giller, Kenneth A. Kobak, David S. Reasner

Publikováno v: Journal of clinical psychopharmacology. 35(6)

Lack of standardization across sites and raters, poor interrater reliability, and possible scoring bias affecting the primary outcome measure contribute to a high failure rate in anxiety trials. Remote centralized raters who are blinded to protocol i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::385ae53d4a6dad06c4bff77fb939bdca
https://pubmed.ncbi.nlm.nih.gov/26488677

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Ziprasidone in the Treatment of Acute Bipolar Mania: A Three-Week, Placebo-Controlled, Double-Blind, Randomized Trial

Autor: Kathleen Ice, Steven G. Potkin, Earl L. Giller, Marcio Versiani, Paul E. Keck, Scott A. West

Publikováno v: American Journal of Psychiatry. 160:741-748

The study evaluated the efficacy and tolerability of ziprasidone, compared with placebo, in the treatment of adult patients with acute bipolar mania.Patients with a primary DSM-IV diagnosis of bipolar I disorder and a current manic or mixed episode (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b6f54fbefef30bc97616b54a88bbf9e
https://doi.org/10.1176/appi.ajp.160.4.741

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Prolactin response to low-dose dexamethasone challenge in combat-exposed veterans with and without posttraumatic stress disorder and normal controls

Autor: James Schmeidler, Rachel Yehuda, Earl L. Giller, Robert G. Grossman, David Boisoneau

Publikováno v: Biological Psychiatry. 40:1100-1105

The prolactin and cortisol responses to dexamethasone (0.5 mg) were studied in combat veterans with (n = 18) and without (n = 12) posttraumatic stress disorder (PTSD) and normal controls (n = 18). Both veteran groups demonstrated greater prolactin su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb44307e57dc8a6298f598e601635bdf
https://doi.org/10.1016/s0006-3223(95)00600-1

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Dissociation in aging Holocaust survivors

Autor: Steven M. Southwick, Rachel Yehuda, Earl L. Giller, Karen Binder-Brynes, Abbie Elkin, James Schmeidler, Boaz Kahana

Publikováno v: American Journal of Psychiatry. 153:935-940

Objective This study explored relationships among dissociation, trauma, and posttraumatic stress disorder (PTSD) in elderly Holocaust survivors with and without PTSD and in a demographically comparable group of nontraumatized subjects. Method Holocau

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a161b13bc8d382fd15b5f5c32379518
https://doi.org/10.1176/ajp.153.7.935

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Low urinary cortisol excretion in Holocaust survivors with posttraumatic stress disorder

Autor: Steven M. Southwick, Boaz Kahana, Earl L. Giller, Shelly Zemelman, Rachel Yehuda, Karen Binder-Brynes

Publikováno v: American Journal of Psychiatry. 152:982-986

Objective: The authors’ objective was to compare the urinary cortisol excretion of Holocaust survivors with posttraumatic stress disorder (PTSD) (N=22) to that ofHolocaust survivors without PTSD (N=25) and comparison subjects not exposed to the Hol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5413745ffd15b10c120df3c632b06013
https://doi.org/10.1176/ajp.152.7.982

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Differential pattern of response in mood symptoms and suicide risk measures in severely ill depressed patients assigned to citalopram with placebo or citalopram combined with lithium: role of lithium levels

Autor: Earl L. Giller, Shirin Khan, Vishaal Mehra, Richard L. Rudolph, James Faucett, Arif Khan, Joy Hobus

Publikováno v: Journal of psychiatric research. 45(11)

The assumption that antidepressants may reduce suicide risk by reducing depressive symptoms is not based on data. Further, it is unclear if the retrospectively based anti-suicidal effects of lithium can be prospectively evaluated using lithium as an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e28fc55f191b323eee2fd72ce8216e7d
https://pubmed.ncbi.nlm.nih.gov/21752394

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