Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Earl L. Branum"'
Autor:
John F. O'Brien, Irene Meissner, Daniel M. Hoefner, Shannon D. Hodel, Joseph P. McConnell, Earl L. Branum, Deborah Sun
Publikováno v:
Clinical Chemistry. 47:266-274
Background: Recent evidence suggests that the presence of small, dense LDL is independently associated with increased risk of developing coronary artery disease. Current methods to subfractionate LDL are time-consuming and/or technically demanding. T
Publikováno v:
Clinical Chemistry. 36:240-246
To separate liver and bone alkaline phosphatase (ALP) isoenzymes in human serum, we used high-performance affinity chromatography (HPAC) on a column of wheat-germ lectin conjugated to 7-microns-diameter silica particles and an eluent containing N-ace
Autor:
Robert S. Galen, John F. O'Brien, Scott M Hogen, Jennie N. Ward, Stacy J. Hartman, Linnea M. Baudhuin, Irene Meissner, Earl L. Branum, Joseph P. McConnell
Publikováno v:
Clinical biochemistry. 37(6)
Objectives: Elevated plasma lipoprotein(a) [Lp(a)] is a significant risk factor for vascular disease. Standardization of Lp(a) mass measurement is complicated by the heterogeneity of apolipoprotein(a) [apo(a)]. We investigated whether Lp(a) cholester
Autor:
Earl L. Branum, Susan A. Lagerstedt, Jerry A. Katzmann, Joseph P. McConnell, Allan S. Jaffe, Karla V. Ballman
Publikováno v:
Clinical chemistry and laboratory medicine. 40(1)
Two new automated, highly sensitive methods for the measurement of C-reactive protein (CRP) were compared using blood samples from active and retired health care workers (116 males, 114 females). The regression equation was y=1.115x-0.0267 forthe Kam
Autor:
Carol L. Szumlanski, Diane M. Otterness, Lynne Lennard, Earl L. Branum, Richard M. Weinshilboum, B. Klemetsdal, Kjeld Schmiegelow, John T. O'Brien, Jarle Aarbakke, Jeong Ok Park-Hah, Heiko Iven
Publikováno v:
Clinical pharmacology and therapeutics. 62(1)
Thiopurine methyltransferase (TPMT) catalyzes the S-methylation of thiopurine drugs. TPMT activity is regulated by a common genetic polymorphism that is associated with large individual variations in thiopurine toxicity and efficacy. We previously cl
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 199(1)
The newly described high-performance (HPLC) affinity chromatography method for the separation of human bone and liver alkaline phosphatase (ALP, EC 3.1.3.1) isoenzymes was clinically evaluated. The improved resolution of bone from liver isoenzyme and
Publikováno v:
Clinical Chemistry. 35:29-32
We used wheat-germ-lectin affinity chromatography as a tool to investigate the structure of alkaline phosphatase (ALP, EC 3.1.3.1) and to obtain fractions enriched in either bone or liver ALP activity. Liver and bone isoenzymes in serum samples were
Publikováno v:
Clinical Chemistry. 34:110-113
We compared acid citrate-dextrose (ACD-B) and heparin to determine which anticoagulant better preserves leukocytes for lysosomal enzyme assays if processing was done immediately or delayed for 24 h or more. Twenty normal subjects had blood drawn into
Publikováno v:
Cancer. 41:192-200
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 81(21)
Purified type beta transforming growth factor from human platelets (TGF beta) radioiodinated with 125I-labeled Bolton and Hunter reagent was found to bind to a variety of cultured cells of both epithelial and mesenchymal origin, including normal huma