Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Earl E. Ose"'
Autor:
Earl E. Ose, F. T. Counter, R. L. Hamill, John L. Ott, Gene M. Wild, Richard H. Baltz, Herbert A. Kirst
Publikováno v:
The Journal of Antibiotics. 35:1675-1682
Although a substantial number of 16-membered macrolides related to tylosin have now been isolated and evaluated as antibiotics, none appeared to be superior to tylosin in treating bacterial or mycoplasmal infections caused by sensitive organisms. Nev
Autor:
Earl E. Ose
Publikováno v:
The Journal of antibiotics. 40(2)
A new macrolide antibiotic, EL-870, 20-deoxo-20-(3,5-dimethylpiperidin-1-yl)desmycosin, has been prepared by chemical modification of desmycosin. In vitro, against selected animal bacterial pathogens, it inhibited growth of Pasteurella multocida, Pas
Autor:
F. T. Counter, Jeffrey Thomas Vicenzi, Julie A. Wind, K. E. Willard, Satoshi Omura, Crouse Gary D, Manuel Debono, Herbert A. Kirst, Earl E. Ose, Eddie Vi-Ping Tao, John L. Ott
Publikováno v:
The Journal of antibiotics. 42(8)
A series of 20-deoxo-20-cyclic (alkylamino) derivatives of tylosin, desmycosin, macrocin and lactenocin was prepared by reductive amination of the C-20 aldehyde group. The majority of the compounds were prepared using metal hydrides (sodium cyanoboro
Autor:
A. M. Felty-Duckworth, R. S. Pekarek, Manuel Debono, Earl E. Ose, John E. Toth, Herbert A. Kirst, K. E. Willard
Publikováno v:
The Journal of antibiotics. 41(7)
Three series of semi-synthetic derivatives of tylosin-related macrolides were evaluated for utility in veterinary medicine. 23-Modified derivatives of 5-O-mycaminosyltylonolide (OMT) possessed potent activity in vitro against species of Pasteurella a