Výsledky vyhledávání - "Earl C. Richardson"

Specific binding of concanavalin A to free inositol and liposomes containing phosphatidylinositol

Autor: Earl C. Richardson, Nabila M. Wassef, Carl R. Alving

Publikováno v: Biochemical and Biophysical Research Communications. 130:76-83

We previously reported that concanavalin A could bind specifically to liposomes containing phospholipids and lacking glycoconjugates (Biochem. Biophys. Res. Comm. 74 , 208, 1977). In the present study we show that the binding of concanavalin A to the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e29ddaa617edd54e826fd1285a744c50
https://doi.org/10.1016/0006-291x(85)90384-5

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Life-Long Administration of Liposomes and Lipid A in Mice: Effects on Longevity, Antibodies to Liposomes, and Terminal Histopathological Patterns

Autor: Glenn M. Swartz, Earl C. Richardson, Carl R. Alving, James B. Moe

Publikováno v: Journal of Liposome Research. 1:93-110

Long-term effects of life-long (>2 year) repeated intravenous injections (up to 17) of high doses of liposomes, lipid A, or liposomes containing lipid A were assessed in BALB/c mice. the liposomes contained dipalmitoylphosphatidylcholine, and cholest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c6b45a994e02e84b279f17734835b321
https://doi.org/10.3109/08982108809035984

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A Correlation between Radiation-induced Free Radicals and Survival in Micro-organisms Exposed to β-mercaptoethylamine under Oxygen or Nitrogen

Autor: Earl C. Richardson, Harold M. Swartz

Publikováno v: International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine. 12:75-88

SummaryBoth free radical and survival measurements were made on the same samples of micro-organisms irradiated at −196°c. Under these conditions, which minimized indirect effects, pronounced oxygen (radiosensitization) and MEA (radioprotection) ef

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::01f3fd3891b88ba1b77f1eb72b40b8ed
https://doi.org/10.1080/09553006614551391

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Radioprotective effects of lipid A, liposomes, and liposomes containing lipid A in mice

Autor: Earl C. Richardson, Carl R. Alving

Publikováno v: Biochimica et biophysica acta. 903(3)

Lipid A from Gram-negative bacterial lipopolysaccharide (endotoxin) was incorporated into liposomal membranes and examined as a prophylactic radioprotectant compound in lethally irradiated mice. Splenic hematopoietic activity, resulting in increased

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1099bf4ed91e1e0b1dbcd9efe943b108
https://pubmed.ncbi.nlm.nih.gov/3311165

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Mitogenic response of lymphocytes from C3H/HeJ mice in the presence of lipid A and lipid A fractions

Autor: Carl R. Alving, Earl C. Richardson

Publikováno v: Reviews of infectious diseases. 6(4)

Purified lipid A and eight fractions of lipid A were examined for the ability to elicit a mitogenic response in spleen lymphocytes of endotoxin-resistant C3H/HeJ mice. The pattern of results obtained with different lipid A fractions was similar to th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4a02677792b0ae6c0e240313f0d582b
https://pubmed.ncbi.nlm.nih.gov/6474013

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Effects of negatively charged lipids on phagocytosis of liposomes opsonized by complement

Autor: Carl R. Alving, Nabila M. Wassef, Frits Roerdink, Earl C. Richardson

Publikováno v: Biochimica et biophysica acta. 734(1)

Ingestion of liposomes opsonized by specific antibody plus complement was investigated in vitro. Although the antibodies alone (IgM) did not have an opsonizing effect, in the presence of such antibodies uptake and ingestion of liposomes by mouse peri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49c2a99fe0a7920931d588ecd068ee04
https://pubmed.ncbi.nlm.nih.gov/6615828

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Enhancement by lipid A of mucosal immunogenicity of liposome-associated cholera toxin

Autor: Earl C. Richardson, John B. Sacci, Nathaniel F. Pierce, Carl R. Alving

Publikováno v: Reviews of infectious diseases. 6(4)

Two methods that might enhance the mucosal immunogenicity of a protein antigen, cholera toxin (CT), were studied in rats: association of CT with liposomes, and coadministration of CT with lipid A. Enteric priming by CT was not enhanced when the antig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::559bf6cf519d5c782f793cc199589e24
https://pubmed.ncbi.nlm.nih.gov/6474016

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Suppression of phagocytic function and phospholipid metabolism in macrophages by phosphatidylinositol liposomes

Autor: Earl C. Richardson, Carl R. Alving, Nabila M. Wassef, Frits H. Roerdink

Increased phagocytosis of complement-opsonized vesicles was accompanied by increased phosphatidylinositol (PtdIns) turnover in murine macrophages. However when PtdIns was also present as one of the lipids in the opsonized liposomes, it reduced both p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::534ba81a297300fb5c7489fa2fdc0225
https://europepmc.org/articles/PMC345128/

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Mitogenic activities of lipid A and liposome-associated lipid A: effects of epitope density

Autor: Earl C. Richardson, Carl R. Alving

Publikováno v: Reviews of infectious diseases. 6(4)

Among eight purified lipid A fractions, there was heterogeneity of mitogenic activity, but the relative activity could not be predicted by limulus amebocyte lysate assay. Analysis of mitogenic activity after the incorporation of lipid A into liposome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::539b02d9631af1ea924675357cd5d5d3
https://pubmed.ncbi.nlm.nih.gov/6206542

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